Sensitivity enhancement in rGO/Mn3O4 hybrid nanocomposites: A modified glassy carbon electrode for the simultaneous detection of dopamine and uric acid

2021 ◽  
Vol 280 ◽  
pp. 116859
Author(s):  
G. Vinodhkumar ◽  
Sujin P. Jose ◽  
S. Lokeswarareddy ◽  
C. Sekar ◽  
I. Vetha Potheher ◽  
...  
Keyword(s):  
Uric Acid ◽  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Simultaneous Detection ◽  
Sensitivity Enhancement ◽  
Hybrid Nanocomposites ◽  
Carbon Electrode ◽  
Modified Glassy Carbon Electrode

Solar Exfoliated Graphene Oxide: A Platform for Electrochemical Sensing of Epinephrine

2020 ◽  
Vol 16 (4) ◽  
pp. 393-403 ◽  
Author(s):  
Renjini Sadhana ◽  
Pinky Abraham ◽  
Anithakumary Vidyadharan
Keyword(s):  
Cyclic Voltammetry ◽  
Graphene Oxide ◽  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Simultaneous Detection ◽  
Differential Pulse ◽  
Carbon Electrode ◽  
Modified Glassy Carbon Electrode ◽  
Reduced Graphene ◽  
Pulse Voltammetry

Introduction: In this study, solar exfoliated graphite oxide modified glassy carbon electrode was used for the anodic oxidation of epinephrine in a phosphate buffer medium at pH7. The modified electrode showed fast response and sensitivity towards Epinephrine Molecule (EP). The electrode was characterized electrochemically through Cyclic Voltammetry (CV) and Differential Pulse Voltammetry (DPV). Area of the electrode enhanced three times during modification and studies reveal that the oxidation process of EP occurs by an adsorption controlled process involving two electrons. The results showed a detection limit of 0.50 ± 0.01μM with a linear range up to 100 μM. The rate constant calculated for the electron transfer reaction is 1.35 s-1. The electrode was effective for simultaneous detection of EP in the presence of Ascorbic Acid (AA) and Uric Acid (UA) with well-resolved signals. The sensitivity, selectivity and stability of the sensor were also confirmed. Methods: Glassy carbon electrode modified by reduced graphene oxide was used for the detection and quantification of epinephrine using cyclic voltammetry and differential pulse voltammetry. Results: The results showed an enhancement in the electrocatalytic oxidation of epinephrine due to the increase in the effective surface area of the modified electrode. The anodic transfer coefficient, detection limit and electron transfer rate constant of the reaction were also calculated. Conclusion: The paper reports the determination of epinephrine using reduced graphene oxide modified glassy carbon electrode through CV and DPV. The sensor exhibited excellent reproducibility and repeatability for the detection of epinephrine and also its simultaneous detection of ascorbic acid and uric acid, which coexist in the biological system.

The Electrochemical Properties of Co(TPP), Tetraphenylborate Modified Glassy Carbon Electrode: Application to Dopamine and Uric Acid Analysis

2006 ◽  
Vol 18 (5) ◽  
pp. 440-448 ◽  
Author(s):  
Yunlong Zeng ◽  
Chunxiang Li ◽  
Chunran Tang ◽  
Xiao-Bing Zhang ◽  
Guoli Shen ◽  
...  
Keyword(s):  
Uric Acid ◽  
Electrochemical Properties ◽  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Carbon Electrode ◽  
Modified Glassy Carbon Electrode
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