A DFT study of the asymmetric (S)-5-(pyrrolidin-2-yl)-1H-tetrazole catalyzed Michael addition of carbonyl compounds to nitroalkenes

2007 ◽  
Vol 18 (2) ◽  
pp. 157-164 ◽  
Author(s):  
Manuel Arnó ◽  
Ramón J. Zaragozá ◽  
Luis R. Domingo
Keyword(s):  
Michael Addition ◽  
Carbonyl Compounds ◽  
Dft Study

scholarly journals Michael addition of carbonyl compounds to nitroolefins under the catalysis of new pyrrolidine-based bifunctional organocatalysts

2018 ◽  
Vol 16 (6) ◽  
pp. 924-935 ◽  
Author(s):  
A. Castán ◽  
R. Badorrey ◽  
J. A. Gálvez ◽  
P. López-Ram-de-Víu ◽  
M. D. Díaz-de-Villegas
Keyword(s):  
Michael Addition ◽  
Carbonyl Compounds ◽  
Asymmetric Michael Addition ◽  
Aldehydes And Ketones

Novel bifunctional pyrrolidine-based organocatalysts applicable for the asymmetric Michael addition of aldehydes and ketones to nitroolefins have been developed.

scholarly journals Nucleofugal behavior of a β-shielded α-cyanovinyl carbanion

2018 ◽  
Vol 14 ◽  
pp. 3018-3024
Author(s):  
Rudolf Knorr ◽  
Barbara Schmidt
Keyword(s):  
Michael Addition ◽  
Carbonyl Compounds ◽  
Room Temperature ◽  
Experimental Conditions ◽  
Metal Free ◽  
Metal Derivatives ◽  
Carbonyl Addition ◽  
Derivatives Of

Sterically well-shielded against unsolicited Michael addition and polymerization reactions, α-metalated α-(1,1,3,3-tetramethylindan-2-ylidene)acetonitriles added reversibly to three small aldehydes and two bulky ketones at room temperature. Experimental conditions were determined for transfer of the nucleofugal title carbanion unit between different carbonyl compounds. These readily occurring retro-additions via C–C(O) bond fission may also be used to generate different metal derivatives of the nucleofugal anions as equilibrium components. Fluoride-catalyzed, metal-free desilylation admitted carbonyl addition but blocked the retro-addition.

A Natural Phosphate and Doped-Catalyzed Michael Addition of Mercaptans to α,β-Unsaturated Carbonyl Compounds.

ChemInform ◽  
2003 ◽  
Vol 34 (13) ◽  
Author(s):  
Younes Abrouki ◽  
Mohamed Zahouily ◽  
Ahmed Rayadh ◽  
Bouchaib Bahlaouan ◽  
Said Sebti
Keyword(s):  
Michael Addition ◽  
Carbonyl Compounds ◽  
Natural Phosphate
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