Cerebral infarction and iron deficiency anemia due to uterine myoma in two middle-aged women with histidine-rich glycoprotein deficiency

2020 ◽  
Vol 191 ◽  
pp. 30-33
Author(s):  
Toshio Shigekiyo ◽  
Hikaru Yagi ◽  
Etsuko Sekimoto ◽  
Hironobu Shibata ◽  
Shuji Ozaki ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Cerebral Infarction ◽  
Iron Deficiency Anemia ◽  
Uterine Myoma ◽  
Deficiency Anemia ◽  
Middle Aged

scholarly journals A Case of Acute Ischemic Stroke Associated with Hookworm Anemia.

2021 ◽  
Author(s):  
Jiang-qiong Ke ◽  
Huicong Huang ◽  
Guangyao Zhou ◽  
Yan Li ◽  
Shengmin Shao ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Ischemic Stroke ◽  
Iron Deficiency ◽  
Cerebral Infarction ◽  
Acute Ischemic Stroke ◽  
Iron Deficiency Anemia ◽  
Deficiency Anemia ◽  
Cerebral Stroke ◽  
Parasitic Diseases ◽  
Normal Brain

Abstract Background: Hookworm disease discovered in a patient presenting with cerebral infarction due to severe iron-deficiency anemia and confirmed by gastroduodenoscopy has not been reported especially with negative stool routine. Case presentation: We report a male patient who presented himself to us with acute cerebral stroke verified as hookworm disease. Routine laboratory tests revealed low Hemoglobin (Hb) concentration but stool routine and occult blood test were normal. Brain magnetic resonance imaging (MRI) showed left-sided parietal-occipital lobe and centrum semiovale (“watershed”) infarction verified the diagnosis of acute ischemic stroke. Bone marrow aspiration showed proliferative bone marrow image with obvious red system hyperplasia. Gastroduodenoscopy discovered adult hematophagic hookworms in the bulb and descending part of duodenum of the patient. A series of conservative drug treatment was initiated and the patient was subsequently treated with albendazole after the gastroduodenoscopy. Twenty-five days later, the patient's physical function improved gradually and he was discharged without neurological deficit. Conclusion: Hookworm disease could be manifest in acute ischemic stroke. It was concluded that patients with severe iron-deficiency anemia should also be examined for rare intestinal parasitic diseases. Screening for these intestinal parasitic diseases in patients presenting with cerebral infarction and anemia could effectively avoid misdiagnosis and make increase the efficacy of treatment.

scholarly journals Cerebral Ischemia due to Aortic Arch Thrombosis Secondary to Iron Deficiency Anemia

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Taha Nisar ◽  
Rajanigandhi Hanumanthu
Keyword(s):  
Cerebral Ischemia ◽  
Iron Deficiency ◽  
Aortic Arch ◽  
Iron Deficiency Anemia ◽  
Hypercoagulable State ◽  
Deficiency Anemia ◽  
Middle Aged ◽  
Transesophageal Echocardiogram ◽  
Iron Replacement

Thrombocytosis, hypercoagulable state, and hypoxia secondary to anemia are some of the mechanisms that are thought to cause strokes in patients with iron deficiency anemia (IDA). Several cases of middle-aged females with IDA who had embolic strokes due to aortic arch thrombosis have been reported. Majority of the cases were treated with anticoagulation. We report another case of embolic strokes in a patient with IDA treated with anticoagulation and iron replacement without recurrence of further episodes. We concluded that embolic phenomenon in middle-aged females with IDA warrants transesophageal echocardiogram with an evaluation of aortic arch.

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