Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?

Trends in Biochemical Sciences ◽

10.1016/j.tibs.2015.08.006 ◽

2015 ◽

Vol 40 (11) ◽

pp. 701-714 ◽

Author(s):

Agnel Sfeir ◽

Lorraine S. Symington

Keyword(s):

End Joining ◽

Survival Mechanism

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Faculty Opinions recommendation of Identification of a DNA nonhomologous end-joining complex in bacteria.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1009303.122808 ◽

2002 ◽

Author(s):

Martin Marinus

Keyword(s):

Nonhomologous End Joining ◽

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Faculty Opinions recommendation of A RAP1/TRF2 complex inhibits nonhomologous end-joining at human telomeric DNA ends.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1085988.538938 ◽

2007 ◽

Author(s):

Joachim Lingner

Keyword(s):

Nonhomologous End Joining ◽

End Joining ◽

Telomeric Dna ◽

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Faculty Opinions recommendation of Bcl2 negatively regulates DNA double-strand-break repair through a nonhomologous end-joining pathway.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1104438.560671 ◽

2008 ◽

Author(s):

Carlos Telleria

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Nonhomologous End Joining ◽

Double Strand Break Repair ◽

End Joining ◽

Dna Double Strand Break ◽

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Faculty Opinions recommendation of Preventing nonhomologous end joining suppresses DNA repair defects of Fanconi anemia.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.4015985.793492297 ◽

2014 ◽

Author(s):

Wade Clapp ◽

Grzegorz Nalepa

Keyword(s):

Fanconi Anemia ◽

Nonhomologous End Joining ◽

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Faculty Opinions recommendation of Mitochondrial genome maintenance: roles for nuclear nonhomologous end-joining proteins in Saccharomyces cerevisiae.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717960423.793463474 ◽

2012 ◽

Author(s):

Lucio Comai

Keyword(s):

Saccharomyces Cerevisiae ◽

Mitochondrial Genome ◽

Nonhomologous End Joining ◽

Genome Maintenance ◽

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Faculty Opinions recommendation of An inhibitor of nonhomologous end-joining abrogates double-strand break repair and impedes cancer progression.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717968609.793470336 ◽

2013 ◽

Author(s):

Fabrizio d'Adda di Fagagna ◽

Francesca Rossiello

Keyword(s):

Cancer Progression ◽

Strand Break ◽

Double Strand Break ◽

Nonhomologous End Joining ◽

Double Strand Break Repair ◽

End Joining ◽

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Faculty Opinions recommendation of A regulatory role for the cohesin loader NIPBL in nonhomologous end joining during immunoglobulin class switch recombination.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718151470.793487410 ◽

2013 ◽

Author(s):

Craig Bassing

Keyword(s):

Class Switch Recombination ◽

Nonhomologous End Joining ◽

Regulatory Role ◽

End Joining ◽

Immunoglobulin Class ◽

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Faculty Opinions recommendation of Chromatin reader Brd4 functions in Ig class switching as a repair complex adaptor of nonhomologous end-joining.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718463065.793496905 ◽

2014 ◽

Author(s):

Alberto Martin ◽

Michael Le

Keyword(s):

Nonhomologous End Joining ◽

Class Switching ◽

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Faculty Opinions recommendation of Akt-mediated phosphorylation of XLF impairs non-homologous end-joining DNA repair.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725347092.793503938 ◽

2015 ◽

Author(s):

Susan Lees-Miller

Keyword(s):

End Joining ◽

Non Homologous End Joining

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Faculty Opinions recommendation of Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726318081.793518723 ◽

2016 ◽

Author(s):

Cecilia Moens

Keyword(s):

Double Strand Breaks ◽

Dna Double Strand Breaks ◽

End Joining ◽

Strand Breaks ◽

Zebrafish Development

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