scholarly journals TRPC5 and the path towards analgesic drug development

2021 ◽  
Author(s):  
Franziska Denk
Keyword(s):  
Drug Development ◽  
Analgesic Drug

Functional genomics of pain in analgesic drug development and therapy

2013 ◽  
Vol 139 (1) ◽  
pp. 60-70 ◽  
Author(s):  
Jörn Lötsch ◽  
Alexandra Doehring ◽  
Jeffrey S. Mogil ◽  
Torsten Arndt ◽  
Gerd Geisslinger ◽  
...  
Keyword(s):  
Drug Development ◽  
Functional Genomics ◽  
Analgesic Drug

scholarly journals Erratum: Breaking barriers to novel analgesic drug development

2017 ◽  
Vol 16 (11) ◽  
pp. 810-810 ◽  
Author(s):  
Ajay S. Yekkirala ◽  
David P. Roberson ◽  
Bruce P. Bean ◽  
Clifford J. Woolf
Keyword(s):  
Drug Development ◽  
Analgesic Drug

Hypernociceptive role of cytokines and chemokines: Targets for analgesic drug development?

2006 ◽  
Vol 112 (1) ◽  
pp. 116-138 ◽  
Author(s):  
Waldiceu A. Verri ◽  
Thiago M. Cunha ◽  
Carlos A. Parada ◽  
Stephen Poole ◽  
Fernando Q. Cunha ◽  
...  
Keyword(s):  
Drug Development ◽  
Analgesic Drug ◽  
Cytokines And Chemokines

scholarly journals The translatability of pain across species

2019 ◽  
Vol 374 (1785) ◽  
pp. 20190286 ◽  
Author(s):  
Jeffrey S. Mogil
Keyword(s):  
Drug Development ◽  
Species Differences ◽  
Research Literature ◽  
Genetic Effects ◽  
Analgesic Drug ◽  
Pain Memory ◽  
Pain Research ◽  
Social Modulation ◽  
The Poor ◽  
Species Similarity

The poor translational record of pain research has suggested to some observers that species differences in pain biology might be to blame. In this review, I consider the evidence for species similarity and differences in the pain research literature. Impressive feats of translation have been demonstrated in relation to certain genetic effects, social modulation of pain and pain memory. The degree to which pain biology in rodents predicts pain biology in humans has important implications both for evolutionary accounts of pain, but also the success of analgesic drug development going forward. This article is part of the Theo Murphy meeting issue ‘Evolution of mechanisms and behaviour important for pain’.

scholarly journals Identifying biological markers of activity in human nociceptive pathways to facilitate analgesic drug development

Pain ◽  
2008 ◽  
Vol 140 (2) ◽  
pp. 249-253 ◽  
Author(s):  
Boris A. Chizh ◽  
Joel D. Greenspan ◽  
Kenneth L. Casey ◽  
Michael I. Nemenov ◽  
Rolf-Detlef Treede
Keyword(s):  
Drug Development ◽  
Biological Markers ◽  
Analgesic Drug ◽  
Nociceptive Pathways
Sign in / Sign up

Export Citation Format

Share Document