Data management in large-scale collaborative toxicity studies: How to file experimental data for automated statistical analysis

2013 ◽  
Vol 27 (4) ◽  
pp. 1402-1409 ◽  
Author(s):  
Sven Stanzel ◽  
Marc Weimer ◽  
Annette Kopp-Schneider
2018 ◽  
Vol 26 (4) ◽  
pp. 1435 ◽  
Author(s):  
Yi Xu ◽  
Hong Gao

Abstract: This paper introduces FormantPro, a Praat-based tool for large-scale, systematic analysis of formant movements, especially for experimental data. The program generates a rich set of output metrics, including continuous contours like time-normalized formant trajectories and formant velocity profiles suitable for direct graphical comparisons, and discrete measurements suitable for statistical analysis. It also allows users to generate mean trajectories and discrete measurements averaged across repetitions and speakers. As an illustration of its usage, data from a preliminary study of syllable segmentation in Mandarin were presented. The alignment of continuous formant trajectories enabled by FormantPro provides evidence that the temporal scopes of consonants and vowels are very different from those based on conventional views, and that acoustic and articulatory boundaries of segments are fundamentally similar.Keywords: FormantPro; formant trajectories; syllable segmentation.Resumo: Este artigo apresenta o FormantPro, uma ferramenta que roda no Praat, dedicada à análise sistemática e em larga escala dos movimentos de formantes, especialmente para dados de natureza experimental. O programa gera um rico conjunto de métricas de saída, incluindo contornos contínuos, como as trajetórias de formantes normalizadas temporalmente e perfis de velocidade de formantes adequados para comparações gráficas diretas, bem como medidas discretas adequadas para a análise estatística. O programa também permite aos usuários gerar médias de trajetórias e medidas discretas calculadas a partir das médias de repetições e de falantes. Como ilustração da sua usabilidade, dados preliminares de um estudo sobre segmentação silábica em mandarim foram apresentados. O alinhamento de trajetórias contínuas de formantes geradas pelo FormantPro oferecem evidência de que os escopos temporais de consoantes e vogais são muito diferentes daqueles baseados em visões convencionais, e de que as fronteiras acústicas e articulatórias dos segmentos são fundamentalmente semelhantes.Palavras-chave: FormantPro; trajetórias dos formantes; segmentação silábica


SoftwareX ◽  
2021 ◽  
Vol 15 ◽  
pp. 100747
Author(s):  
José Daniel Lara ◽  
Clayton Barrows ◽  
Daniel Thom ◽  
Dheepak Krishnamurthy ◽  
Duncan Callaway

2011 ◽  
Vol 8 (2) ◽  
pp. 85-94
Author(s):  
Hendrik Mehlhorn ◽  
Falk Schreiber

Summary DBE2 is an information system for the management of biological experiment data from different data domains in a unified and simple way. It provides persistent data storage, worldwide accessibility of the data and the opportunity to load, save, modify, and annotate the data. It is seamlessly integrated in the VANTED system as an add-on, thereby extending the VANTED platform towards data management. DBE2 also utilizes controlled vocabulary from the Ontology Lookup Service to allow the management of terms such as substance names, species names, and measurement units, aiming at an eased data integration.


Author(s):  
David Forbes ◽  
Gary Page ◽  
Martin Passmore ◽  
Adrian Gaylard

This study is an evaluation of the computational methods in reproducing experimental data for a generic sports utility vehicle (SUV) geometry and an assessment on the influence of fixed and rotating wheels for this geometry. Initially, comparisons are made in the wake structure and base pressures between several CFD codes and experimental data. It was shown that steady-state RANS methods are unsuitable for this geometry due to a large scale unsteadiness in the wake caused by separation at the sharp trailing edge and rear wheel wake interactions. unsteady RANS (URANS) offered no improvements in wake prediction despite a significant increase in computational cost. The detached-eddy simulation (DES) and Lattice–Boltzmann methods showed the best agreement with the experimental results in both the wake structure and base pressure, with LBM running in approximately a fifth of the time for DES. The study then continues by analysing the influence of rotating wheels and a moving ground plane over a fixed wheel and ground plane arrangement. The introduction of wheel rotation and a moving ground was shown to increase the base pressure and reduce the drag acting on the vehicle when compared to the fixed case. However, when compared to the experimental standoff case, variations in drag and lift coefficients were minimal but misleading, as significant variations to the surface pressures were present.


2006 ◽  
Vol 141 (3) ◽  
pp. 811-824 ◽  
Author(s):  
Sunchung Park ◽  
Nobuko Sugimoto ◽  
Matthew D. Larson ◽  
Randy Beaudry ◽  
Steven van Nocker

2021 ◽  
Author(s):  
Gaston Latessa ◽  
Angela Busse ◽  
Manousos Valyrakis

<p>The prediction of particle motion in a fluid flow environment presents several challenges from the quantification of the forces exerted by the fluid onto the solids -normally with fluctuating behaviour due to turbulence- and the definition of the potential particle entrainment from these actions. An accurate description of these phenomena has many practical applications in local scour definition and to the design of protection measures.</p><p>In the present work, the actions of different flow conditions on sediment particles is investigated with the aim to translate these effects into particle entrainment identification through analytical solid dynamic equations.</p><p>Large Eddy Simulations (LES) are an increasingly practical tool that provide an accurate representation of both the mean flow field and the large-scale turbulent fluctuations. For the present case, the forces exerted by the flow are integrated over the surface of a stationary particle in the streamwise (drag) and vertical (lift) directions, together with the torques around the particle’s centre of mass. These forces are validated against experimental data under the same bed and flow conditions.</p><p>The forces are then compared against threshold values, obtained through theoretical equations of simple motions such as rolling without sliding. Thus, the frequency of entrainment is related to the different flow conditions in good agreement with results from experimental sediment entrainment research.</p><p>A thorough monitoring of the velocity flow field on several locations is carried out to determine the relationships between velocity time series at several locations around the particle and the forces acting on its surface. These results a relevant to determine ideal locations for flow investigation both in numerical and physical experiments.</p><p>Through numerical experiments, a large number of flow conditions were simulated obtaining a full set of actions over a fixed particle sitting on a smooth bed. These actions were translated into potential particle entrainment events and validated against experimental data. Future work will present the coupling of these LES models with Discrete Element Method (DEM) models to verify the entrainment phenomena entirely from a numerical perspective.</p>


2004 ◽  
Vol 61 (1) ◽  
pp. 118-124 ◽  
Author(s):  
Maria Cristina Stolf Nogueira

The single degree of freedom of orthogonal contrasts is a useful technique for the analysis of experimental data and helpful in obtaining estimates of main, nested and interaction effects, for mean comparisons between groups of data and in obtaining specific residuals. Furthermore, the application of orthogonal contrasts is an alternative way of doing statistical analysis on data from non-conventional experiments, whithout a definite structure. To justify its application, an extensive review is made on the definitions and concepts involving contrasts.


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