A novel MDCKII in vitro model for assessing ABCG2-drug interactions and regulation of ABCG2 transport activity in the caprine mammary gland by environmental pollutants and pesticides

2014 ◽  
Vol 28 (3) ◽  
pp. 432-441 ◽  
Author(s):  
Sandra Halwachs ◽  
Louise Wassermann ◽  
Walther Honscha
Keyword(s):  
Mammary Gland ◽  
Drug Interactions ◽  
In Vitro Model ◽  
Environmental Pollutants ◽  
Transport Activity ◽  
Vitro Model

Utility of pooled cryopreserved human enterocytes as an in vitro model for assessing intestinal clearance and drug–drug interactions

2018 ◽  
Vol 33 (1) ◽  
pp. S78 ◽  
Author(s):  
Susan Wong ◽  
Utkarsh Doshi ◽  
Peter Vuong ◽  
Ning Liu ◽  
Suzanne Tay ◽  
...  
Keyword(s):  
Drug Interactions ◽  
In Vitro Model ◽  
Vitro Model

Utility of Pooled Cryopreserved Human Enterocytes as an In vitro Model for Assessing Intestinal Clearance and Drug-Drug Interactions

2018 ◽  
Vol 12 (1) ◽  
pp. 3-13 ◽  
Author(s):  
Susan Wong ◽  
Utkarsh Doshi ◽  
Peter Vuong ◽  
Ning Liu ◽  
Suzanne Tey ◽  
...  
Keyword(s):  
Drug Interactions ◽  
In Vitro Model ◽  
Vitro Model

scholarly journals Understanding mammary gland functioning in livestock species using in-vitro mammary epithelial cells model -An overview

2013 ◽  
Vol 3 (1) ◽  
pp. 160-168
Author(s):  
M Mukesh ◽  
Umesh Kumar Shandilya ◽  
Monika Sodhi ◽  
Ankita Sharma ◽  
Neha Kapila
Keyword(s):  
Mammary Gland ◽  
Epithelial Cells ◽  
Cell Line ◽  
In Vitro Model ◽  
Mammary Epithelial Cells ◽  
Branching Morphogenesis ◽  
Mammary Epithelial ◽  
Livestock Species ◽  
Vitro Model

Understanding the mechanisms of the development of the mammary gland can increase the efficiency of milk production, as well as improve animal health. Mammary epithelial cells (MEC) are the functional unit of the mammary gland. Although, there is a well-established MEC cell line, known as MAC-T, the use of a primary cell line is preferred because it more closely mimics an in vivo model. This review focuses on utilization of MECs as a potential in vitro model to better understand mammary gland functions in livestock species. Recently, considerable advances in three dimensional modeling of the mammary gland have been made with the used of extracellular matrix for the study of branching morphogenesis which may enable rapid advances in our understanding of mammary gland biology. Progress in the exploitation of MECs as in vitro model is more productive than ever, however further research is vital.    

scholarly journals An in vitro model of epithelial cell growth stimulation in the rodent mammary gland

2003 ◽  
Vol 36 (4) ◽  
pp. 177-190 ◽  
Author(s):  
U. K. Ehmann ◽  
J. T. DeVries ◽  
M. S. C. Chen ◽  
A. A. Adamos ◽  
R. C. Guzman ◽  
...  
Keyword(s):  
Mammary Gland ◽  
Cell Growth ◽  
Epithelial Cell ◽  
In Vitro Model ◽  
Growth Stimulation ◽  
Vitro Model
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