Spider toxin peptide lycosin-i functionalized gold nanoparticles for in vivo tumor targeting and therapy

Toxicon ◽  
2019 ◽  
Vol 158 ◽  
pp. S2
Author(s):  
Huaxin Tan ◽  
Yazhou Huang ◽  
Jianghong Xu ◽  
Bo Chen ◽  
Peng Zhang ◽  
...  
Theranostics ◽  
2017 ◽  
Vol 7 (12) ◽  
pp. 3168-3178 ◽  
Author(s):  
Huaxin Tan ◽  
Yazhou Huang ◽  
Jianghong Xu ◽  
Bo Chen ◽  
Peng Zhang ◽  
...  

2019 ◽  
Vol Volume 14 ◽  
pp. 5017-5032 ◽  
Author(s):  
Shenting Zhu ◽  
Lingxin Zhu ◽  
Jingjing Yu ◽  
Yanqing Wang ◽  
Bin Peng

Biomaterials ◽  
2016 ◽  
Vol 108 ◽  
pp. 35-43 ◽  
Author(s):  
Xiaoqian Ge ◽  
Zheng-Mei Song ◽  
Lining Sun ◽  
Yi-Fan Yang ◽  
Liyi Shi ◽  
...  

2011 ◽  
Vol 22 (4) ◽  
pp. 664-672 ◽  
Author(s):  
Daniela Arosio ◽  
Leonardo Manzoni ◽  
Elena M. V. Araldi ◽  
Carlo Scolastico

Nanomedicine ◽  
2019 ◽  
Vol 14 (3) ◽  
pp. 317-333 ◽  
Author(s):  
Sha Li ◽  
Sandra Bouchy ◽  
Sebastien Penninckx ◽  
Riccardo Marega ◽  
Ornella Fichera ◽  
...  

Nanomedicine ◽  
2019 ◽  
Vol 14 (22) ◽  
pp. 2941-2955 ◽  
Author(s):  
Xiaju Cheng ◽  
Rui Sun ◽  
Huawei Xia ◽  
Jianan Ding ◽  
Ling Yin ◽  
...  

Aim: We aimed to characterize the tumor-targeting and radiosensitization properties of the photo-responsive gold nanoparticles (AuNPs) decorated photolabile diazirine group and folic acid for improved radiotherapy and computed tomography imaging of tumors. Methods: Folic acid and photolabile diazirine group were covalently conjugated on the surface of AuNPs to afford the desired photo-responsive dAuNP-FA (AuNPs capped with poly(ethylene) glycol ligands bearing photolabile diazirine group and folic acid). The probes were intravenously injected into tumor-bearing mice followed by photocrosslinking upon 405 nm laser irradiation for radiotherapy and computed tomography imaging of tumors in vivo. Results: Light-triggered crosslinking of AuNPs in vivo remarkably enhanced the accumulation and retention of AuNPs within tumors. Conclusion: We have successfully developed a novel photo-responsive Au particle-based tumor theranostic probe showing remarkably improved tumor targeting ability and radiosensitization effect.


2015 ◽  
Vol 6 (8) ◽  
pp. 4934-4939 ◽  
Author(s):  
Zhanghua Zeng ◽  
Shin Mizukami ◽  
Katsumasa Fujita ◽  
Kazuya Kikuchi

An enzyme-responsive NIR nanosystem based on MEF was fabricated by surface functionalization of gold nanoparticles. Sensors based on this strategy are promising for enzyme detection in early diagnostic imaging and in vivo applications.


2019 ◽  
Vol 7 (3) ◽  
pp. 773-788 ◽  
Author(s):  
Suresh Kumar Gulla ◽  
Bonda Rama Rao ◽  
Gopikrishna Moku ◽  
Sudhakar Jinka ◽  
Narendra Varma Nimmu ◽  
...  

Gold nanoparticles functionalized with a thiol ligand containing both mannose mimicking shikimoyl- and transfection enhancing guanidinyl-functionalities forin vivodelivery of DNA vaccines to dendritic cells.


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