Splenic rupture and subsequent splenectomy in a young healthy victim following Russell’s viper bite

Toxicon ◽  
2021 ◽  
Author(s):  
Subramanian Senthilkumaran ◽  
Pradeep Vijayakumar ◽  
Ravi Savania ◽  
Rajendran Vaiyapuri ◽  
Namasivayam Elangovan ◽  
...  
Keyword(s):  
Splenic Rupture ◽  
Russell’S Viper

Autoprothrombin C Activity from Prothrombin with Snake Venom or Trypsin

1962 ◽  
Vol 08 (03) ◽  
pp. 425-433 ◽  
Author(s):  
Ewa Marciniak ◽  
Edmond R Cole ◽  
Walter H Seegers
Keyword(s):  
Snake Venom ◽  
Thrombolytic Agent ◽  
Sodium Citrate ◽  
Specific Activity ◽  
High Specific Activity ◽  
Citrate Solution ◽  
Clotting Factors ◽  
Activation Products ◽  
Russell’S Viper ◽  
Autoprothrombin C

SummarySuitable conditions were found for the generation of autoprothrombin C from purified prothrombin with the use of Russell’s viper venom or trypsin. DEAE chromatographed prothrombin is structurally altered and has never been found to yield autoprothrombin C and also did not yield it when Russell’s viper venom or trypsin were used. Autoprothrombin C is derived from prothrombin with tissue extract thromboplastin, but not in large amounts with the intrinsic clotting factors. With the latter thrombin and autoprothrombin III are the chief activation products. Autoprothrombin III concentrates were prepared from serum and upon activation with 25% sodium citrate solution or with Russell’s viper venom large amounts of autoprothrombin C were obtained, and this was of high specific activity. Theoretically trypsin is not a thrombolytic agent, but on the contrary should lead to intravascular clotting.

Spontaneous splenic rupture occurring as a complication of symptomfree infections mononucleosis

2007 ◽  
Vol 148 (29) ◽  
pp. 1381-1384 ◽  
Author(s):  
Márta Szokó ◽  
András Matolcsy ◽  
Gábor Kovács ◽  
Gábor Simon
Keyword(s):  
Splenic Rupture ◽  
Spontaneous Splenic Rupture ◽  
Epstein Barr

A lépruptura a mononucleosis infectiosa ritka szövődménye, a betegek 0,1–0,5%-ánál következik be. Ez a betegség leggyakoribb halálos komplikációja. A mononucleosisra jellemző egyéb tünetek nélkül kialakuló spontán lépruptura különösen ritka, váratlan bekövetkezése miatt a fatális kimenetel lehetőségével fenyeget. A szerzők egy 16 éves, spontán lépruptura miatt splenectomizált fiú esetét ismertetik, akinél a szerológiai vizsgálatok friss Epstein–Barr-vírusinfekciót igazoltak, a mononucleosis infectiosa egyéb tünetei, jelei nélkül. Áttekintik a mononucleosisban kialakuló lépruptura diagnosztikáját és kezelését.

The Effect of Immunodepletion of Antithrombin III on the Response of Rabbits to Russell's Viper Venom–Induced Activation of Factor X

1997 ◽  
Vol 17 (2) ◽  
pp. 409-416 ◽  
Author(s):  
Samuel I. Rapaport ◽  
Thomas Toneff ◽  
Abraham Rimon ◽  
Bonnie J. Warn-Cramer
Keyword(s):  
Antithrombin Iii ◽  
Factor X ◽  
Russell’S Viper
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