Combined treatment with vitamin C and sulindac synergistically induces p53- and ROS-dependent apoptosis in human colon cancer cells

2016 ◽  
Vol 258 ◽  
pp. 126-133 ◽  
Author(s):  
Eun-Yeung Gong ◽  
Yu Jin Shin ◽  
Ih-Yeon Hwang ◽  
Jeong Hee Kim ◽  
Seung-Mi Kim ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Vitamin C ◽  
Cancer Cells ◽  
Combined Treatment ◽  
Human Colon ◽  
Colon Cancer Cells ◽  
Human Colon Cancer ◽  
Human Colon Cancer Cells

scholarly journals Vitamin C increases the apoptosis via up-regulation p53 during cisplatin treatment in human colon cancer cells

BMB Reports ◽  
2011 ◽  
Vol 44 (3) ◽  
pp. 211-216 ◽  
Author(s):  
Sung-Ho An ◽  
Jung-Hoon Kang ◽  
Dong-Heui Kim ◽  
Myeong-Seon Lee
Keyword(s):  
Colon Cancer ◽  
Vitamin C ◽  
Cancer Cells ◽  
Human Colon ◽  
Colon Cancer Cells ◽  
Human Colon Cancer ◽  
Human Colon Cancer Cells

scholarly journals Resveratrol overcomes TRAIL resistance in human colon cancer cells

2015 ◽  
Vol 10 (3) ◽  
pp. 568
Author(s):  
Xiao-Bing Li ◽  
Yun-Gang Deng ◽  
Jia-Ping Hu ◽  
Zhi Wang ◽  
Rong-Zhen Xie ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cancer Cells ◽  
Combined Treatment ◽  
Human Colon ◽  
Colon Cancer Cells ◽  
Human Colon Cancer ◽  
Trail Receptors ◽  
Normal Human ◽  
Induced Apoptosis ◽  
Human Colon Cancer Cells

<p><strong>Abstract</strong></p> <p><strong> </strong></p> Resveratrol is a stilbenoid compound, and a promising potent chemopreventive bioactive agent. Here, we showed for the first time that the combined treatment with resveratrol and TRAIL drastically induced apoptosis in human colon cancer cells when compared to single treatments. Further, resveratrol markedly up-regulated TRAIL receptors, DR5 and DR4 and the results revealed that DR5 siRNA efficiently blocked apoptosis induced by the co-treatment with resveratrol and TRAIL, indicating that DR5 up-regulation by resveratrol helps to enhance TRAIL actions. In addition, the combined effect were tested on normal human cells. All the obtained results suggested that resveratrol is very useful for TRAIL-based treatments for cancer.

Leptin is a growth factor for human colon cancer cells

2001 ◽  
Vol 120 (5) ◽  
pp. A493-A493
Author(s):  
J HARDWICK ◽  
G VANDENBRINK ◽  
S VANDEVENTER ◽  
M PEPPELENBOSCH
Keyword(s):  
Colon Cancer ◽  
Growth Factor ◽  
Cancer Cells ◽  
Human Colon ◽  
Colon Cancer Cells ◽  
Human Colon Cancer ◽  
Human Colon Cancer Cells

SENP1 participates in Irinotecan resistance in human colon cancer cells

2021 ◽  
Author(s):  
Ming‐Cheng Chen ◽  
Do Chi Nhan ◽  
Chiung‐Hung Hsu ◽  
Tso‐Fu Wang ◽  
Chi‐Cheng Li ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cancer Cells ◽  
Human Colon ◽  
Colon Cancer Cells ◽  
Human Colon Cancer ◽  
Human Colon Cancer Cells

Role of SPARC in the epithelial mesenchymal transition induced by PTHrP in human colon cancer cells

2021 ◽  
pp. 111253
Author(s):  
Pedro Carriere ◽  
Natalia Calvo ◽  
María Belén Novoa ◽  
Fernanda Lopez-Moncada ◽  
Alexander Riquelme ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Cancer Cells ◽  
Epithelial Mesenchymal Transition ◽  
Human Colon ◽  
Colon Cancer Cells ◽  
Human Colon Cancer ◽  
Mesenchymal Transition ◽  
Human Colon Cancer Cells
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