Use of Extracorporeal Membrane Oxygenation Prior to Lung Transplantation Does Not Jeopardize Short-term Survival

2015 ◽  
Vol 47 (9) ◽  
pp. 2737-2742 ◽  
Author(s):  
H.J. Lee ◽  
Y. Hwang ◽  
H.Y. Hwang ◽  
I.K. Park ◽  
C.H. Kang ◽  
...  
Keyword(s):  
Extracorporeal Membrane Oxygenation ◽  
Lung Transplantation ◽  
Short Term ◽  
Term Survival ◽  
Membrane Oxygenation ◽  
Short Term Survival

Extracorporeal Membrane Oxygenation for Primary Graft Dysfunction After Lung Transplantation: Long-Term Survival

2009 ◽  
Vol 87 (3) ◽  
pp. 854-860 ◽  
Author(s):  
Christian A. Bermudez ◽  
Prasad S. Adusumilli ◽  
Kenneth R. McCurry ◽  
Diana Zaldonis ◽  
Maria M. Crespo ◽  
...  
Keyword(s):  
Extracorporeal Membrane Oxygenation ◽  
Lung Transplantation ◽  
Primary Graft Dysfunction ◽  
Graft Dysfunction ◽  
Term Survival ◽  
Long Term Survival ◽  
Membrane Oxygenation

scholarly journals Bridge to lung transplantation using short-term ambulatory extracorporeal membrane oxygenation

2010 ◽  
Vol 140 (3) ◽  
pp. 713-715 ◽  
Author(s):  
Abeel A. Mangi ◽  
David P. Mason ◽  
James J. Yun ◽  
Sudish C. Murthy ◽  
Gosta B. Pettersson
Keyword(s):  
Extracorporeal Membrane Oxygenation ◽  
Lung Transplantation ◽  
Short Term ◽  
Membrane Oxygenation

scholarly journals Long- and short-term clinical impact of awake extracorporeal membrane oxygenation as bridging therapy for lung transplantation

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Nam Eun Kim ◽  
Ala Woo ◽  
Song Yee Kim ◽  
Ah Young Leem ◽  
Youngmok Park ◽  
...  
Keyword(s):  
Extracorporeal Membrane Oxygenation ◽  
Lung Transplantation ◽  
Lung Disease ◽  
Unit Length ◽  
Forced Expiratory Volume ◽  
Clinical Impact ◽  
Short Term ◽  
Bridging Therapy ◽  
Membrane Oxygenation ◽  
End Stage

Abstract Background As lung transplantation (LTx) is becoming a standard treatment for end-stage lung disease, the use of bridging with extracorporeal membrane oxygenation (ECMO) is increasing. We examined the clinical impact of being awake during ECMO as bridging therapy in patients awaiting LTx. Methods In this single-center study, we retrospectively reviewed 241 consecutive LTx patients between October 2012 and March 2019; 64 patients received ECMO support while awaiting LTx. We divided into awake and non-awake groups and compared. Results Twenty-five patients (39.1%) were awake, and 39 (61.0%) were non-awake. The median age of awake patients was 59.0 (interquartile range, 52.5–63.0) years, and 80% of the group was men. The awake group had better post-operative outcomes than the non-awake group: statistically shorter post-operative intensive care unit length of stay [awake vs. non-awake, 6 (4–8.5) vs. 18 (11–36), p < 0.001], longer ventilator free days [awake vs. non-awake, 24 (17–26) vs. 0 (0–15), p < 0.001], and higher gait ability after LTx (awake vs. non-awake, 92% vs. 59%, p = 0.004), leading to higher 6-month and 1-year lung function (forced expiratory volume in 1 s: awake vs. non-awake, 6-month, 77.5% vs. 61%, p = 0.004, 1-year, 75% vs. 57%, p = 0.013). Furthermore, the awake group had significantly lower 6-month and 1-year mortality rates than the non-awake group (6-month 12% vs. 38.5%, p = 0.022, 1-year 24% vs. 53.8%, p = 0.018). Conclusions In patients with end-stage lung disease, considering the long-term and short-term impacts, the awake ECMO strategy could be useful compared with the non-awake ECMO strategy.

Short-term and longer-term survival after veno-arterial extracorporeal membrane oxygenation in an adult patient population: does older age matter?

Perfusion ◽  
2015 ◽  
Vol 31 (5) ◽  
pp. 366-375 ◽  
Author(s):  
David L Narotsky ◽  
Matthew S Mosca ◽  
Heidi Mochari-Greenberger ◽  
James Beck ◽  
Ming Liao ◽  
...  
Keyword(s):  
Extracorporeal Membrane Oxygenation ◽  
Adult Patient ◽  
Patient Population ◽  
Older Age ◽  
Short Term ◽  
Term Survival ◽  
Membrane Oxygenation

Blood Products Transfusion and Mid-Term Outcomes of Lung Transplanted Patients Under Extracorporeal Membrane Oxygenation Support

2018 ◽  
Vol 28 (4) ◽  
pp. 314-321 ◽  
Author(s):  
Tommaso Pettenuzzo ◽  
Giulio Faggi ◽  
Guido Di Gregorio ◽  
Marco Schiavon ◽  
Giuseppe Marulli ◽  
...  
Keyword(s):  
Extracorporeal Membrane Oxygenation ◽  
Lung Transplantation ◽  
Blood Product ◽  
Transfusion Rate ◽  
Term Survival ◽  
Reliable Technique ◽  
Off Pump ◽  
Membrane Oxygenation ◽  
The Impact ◽  
Extracorporeal Support

Introduction: Extracorporeal membrane oxygenation (ECMO) is considered a reliable technique in lung transplantation requiring cardiorespiratory support. However, the impact of this technology on blood product transfusion rate and outcomes compared to off-pump lung transplantation has been rarely investigated. Methods: Between January 2012 and June 2015, 52 elective adult lung transplants were performed at our institution. Of these, 15 recipients required intraoperative venoarterial extracorporeal support and 37 did not. We compared blood product consumption and other outcome variables between the 2 groups. Results: We found comparable in-hospital (86.7% vs 97.3%, P = .14) and 6-month (86.7% vs 91.9%, P = .56) survival between patients with and without extracorporeal support, respectively. Survival at 30 days was lower in the ECMO group (86.7% vs 100%, P = .02). Although patients who underwent ECMO received more intraoperative transfusions, postoperative transfusion rate was similar between the 2 groups. The ECMO group experienced longer mechanical ventilation (median 3 vs 2 days, P = .02) and intensive care unit stay (median 7 vs 5 days, P = .02), besides more cardiogenic shock and deep vein thrombosis. However, we observed no difference in other major and minor in-hospital complications and 6-month complications. Conclusions: In our experience, despite the higher need for intraoperative transfusions, lung transplantation performed with ECMO support is comparable to the off-pump procedure as to short-term survival and outcomes.

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