Temperature-Dependent Differences in the Nonlinear Acoustic Behavior of Ultrasound Contrast Agents Revealed by High-Speed Imaging and Bulk Acoustics

2011 ◽  
Vol 37 (9) ◽  
pp. 1509-1517 ◽  
Author(s):  
Helen Mulvana ◽  
Eleanor Stride ◽  
Mengxing Tang ◽  
Jo V. Hajnal ◽  
Robert Eckersley
Author(s):  
Nicole Anderton ◽  
Craig S Carlson ◽  
Ryunosuke Matsumoto ◽  
Ri-ichiro Shimizu ◽  
Albert T. Poortinga ◽  
...  

Abstract This study explores the rigidity of Pickering-stabilised microbubbles subjected to low-amplitude ultrasound. Such microbubbles might be suitable ultrasound contrast agents. Using an adapted Rayleigh-Plesset equation, we modelled the dynamics of microbubbles with a 7.6-N m−1 shell stiffness under 1-MHz, 0.2-MPa sonication. Such dynamics were observed experimentally, too, using high-speed photography. The maximum expansions were agreeing with those predicted for Pickering-stabilised microbubbles. Subjecting microbubbles to multiple time- delayed pulses yielded the same result. We conclude that Pickering-stabilised microbubbles remain very stable at low acoustic amplitudes.


2010 ◽  
Vol 36 (6) ◽  
pp. 925-934 ◽  
Author(s):  
Helen Mulvana ◽  
Eleanor Stride ◽  
Jo V. Hajnal ◽  
Robert J. Eckersley

Author(s):  
Anush Sridharan ◽  
John R. Eisenbrey ◽  
Flemming Forsberg ◽  
Norbert Lorenz ◽  
Ludwig Steffgen ◽  
...  

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