A Large Scale Validation of Two-Dimensional Shear Wave Elastography in the Diagnosis of Liver Fibrosis Progression in Patients with Chronic Hepatitis B

2017 ◽  
Vol 43 ◽  
pp. S90
Author(s):  
Hong Ding ◽  
Ying Lin ◽  
Yuan Zhuang ◽  
Yue Zhang ◽  
Wenping Wang
Keyword(s):  
Chronic Hepatitis ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Shear Wave ◽  
Chronic Hepatitis B ◽  
Large Scale ◽  
Scale Validation ◽  
Shear Wave Elastography ◽  
Two Dimensional ◽  
Fibrosis Progression

Comparison of Two-Dimensional Shear Wave Elastography with Nine Serum Fibrosis Indices to Assess Liver Fibrosis in Patients with Chronic Hepatitis B: A Prospective Cohort Study

2019 ◽  
Vol 40 (02) ◽  
pp. 237-246 ◽  
Author(s):  
Jianxue Liu ◽  
Yafeng Li ◽  
Xueliang Yang ◽  
Yonghao Ji ◽  
Yaoren Zhang ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Shear Wave ◽  
Chronic Hepatitis B ◽  
Shear Wave Elastography ◽  
Two Dimensional ◽  
Serological Tests ◽  
Distribution Width ◽  
Severe Fibrosis

Abstract Purpose To prospectively assess liver fibrosis with two-dimensional shear wave elastography (2D-SWE) in patients with chronic hepatitis B (CHB) and to compare the performance of this modality with that of serum indices using Scheuer scoring from liver biopsies as the reference standard. Materials and Methods 123 patients with CHB underwent 2D-SWE measurements and serological tests between April 2016 and February 2018. The 2D-SWE and serum indices in the diagnosis of liver fibrosis were assessed using receiver operating characteristic (ROC) analyses. Results The areas under ROC (AUCs) for 2D-SWE, aspartate transaminase-to-platelet ratio index, fibrosis index based on the four factors, Forns score, King’s score, FibroIndex, red cell distribution width-to-platelet ratio, Hepascore, type IV collagen, and hyaluronic acid were 0.851, 0.738, 0.701, 0.739, 0.734, 0.711, 0.692, 0.601, 0.640, and 0.522, respectively, in the diagnosis of substantial fibrosis, 0.975, 0.819, 0.792, 0.829, 0.818, 0.807, 0.732, 0.572, 0.676, and 0.544, respectively, in the diagnosis of severe fibrosis, and 0.972, 0.883, 0.862, 0.908, 0.889, 0.918, 0.808, 0.601, 0.807, and 0.775, respectively, in the diagnosis of cirrhosis. The AUCs of 2D-SWE in the diagnosis of substantial fibrosis, severe fibrosis, and cirrhosis were significantly higher than those of the serum indices (p < 0.05). Conclusion 2D-SWE is a reliable noninvasive method for the assessment of liver fibrosis in patients with CHB with better diagnostic performance than that of nine serum fibrosis indices.

scholarly journals Two-dimensional Shear-Wave Elastography Performance in the Noninvasive Evaluation of Liver Fibrosis in Patients with Chronic Hepatitis B: Comparison with Serum Fibrosis Indexes

Radiology ◽  
2017 ◽  
Vol 283 (3) ◽  
pp. 873-882 ◽  
Author(s):  
Yuan Zhuang ◽  
Hong Ding ◽  
Yue Zhang ◽  
Huichuan Sun ◽  
Chen Xu ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Shear Wave ◽  
Chronic Hepatitis B ◽  
Shear Wave Elastography ◽  
Noninvasive Evaluation ◽  
Two Dimensional

scholarly journals Liver Fibrosis with Two-dimensional US Shear-Wave Elastography in Participants with Chronic Hepatitis B: A Prospective Multicenter Study

Radiology ◽  
2018 ◽  
Vol 289 (2) ◽  
pp. 407-415 ◽  
Author(s):  
Yongyan Gao ◽  
Jian Zheng ◽  
Ping Liang ◽  
Minghui Tong ◽  
Jiabing Wang ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Shear Wave ◽  
Chronic Hepatitis B ◽  
Multicenter Study ◽  
Shear Wave Elastography ◽  
Two Dimensional ◽  
Prospective Multicenter Study

Shear wave elastography for liver fibrosis in chronic hepatitis B: Adapting the cut-offs to alanine aminotransferase levels improves accuracy

2018 ◽  
Vol 29 (2) ◽  
pp. 857-865 ◽  
Author(s):  
Jie Zeng ◽  
Jian Zheng ◽  
Jie-Yang Jin ◽  
Yong-Jiang Mao ◽  
Huan-Yi Guo ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Shear Wave ◽  
Chronic Hepatitis B ◽  
Alanine Aminotransferase ◽  
Shear Wave Elastography

A study of spleen shear-wave elastography in indirect prediction of liver fibrosis in patients with chronic hepatitis B

2020 ◽  
Vol 76 (1) ◽  
pp. 63-72
Author(s):  
Yi Zheng ◽  
Shujun Xia ◽  
Xinping Ren ◽  
Weiwei Zhan ◽  
Zhan Zheng ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Shear Wave ◽  
Chronic Hepatitis B ◽  
Characteristic Curve ◽  
Shear Wave Elastography ◽  
Final Diagnosis ◽  
Predicting Performance ◽  
Reference Index

PURPOSE: To evaluate the value of spleen shear-wave elastography (sound touch elastography [STE], sound touch quantification [STQ]) in indirect prediction of liver fibrosis in patients with chronic hepatitis B (CHB). METHODS: The Young’s modulus (kPa) of spleen STE, STQ and liver FibroScan were measured in 112 patients with CHB. The final diagnosis was according to histological results from liver biopsy based on Scheure G/S scoring system and liver FibroScan was considered as a reference index of prediction efficiency. Grouped by the stage of liver fibrosis, data were analyzed by Spearman correlation analysis, Mann-Whitney test and receiver operating characteristic curve (ROC). RESULTS: Spleen STE was positively correlated with the degree of liver fibrosis, but spleen STQ was not. STEmean and STEmax of spleen were statistically different between the groups categorized by S = 2, S = 3 and S = 4 (all p < 0.05), respectively. Spleen STEmean had the best predicting performance on staging liver fibrosis. The areas under the ROC (AUC) for spleen STEmean were 0.66 (95% confidence interval [CI], 0.56–0.76) for stage S = 2 or higher, 0.72 (95% CI, 0.60–0.83) for S = 3 or higher, 0.83 (95% CI, 0.74–0.92) for S = 4 (all P < 0.01). The differences between the AUC for spleen STEmean and liver FibroScan in liver fibrosis staging were not statistically significant when the groups categorized by S = 2 and S = 4 (P = 0.146 and P = 0.052). But when categorized by S = 3, the evaluating performance of liver FibroScan was better (P = 0.004). CONCLUSION: STEmean of spleen is applicable in indirect predicting fibrosis stage in patients with CHB.

Comparison of 2-D Shear Wave Elastography and Transient Elastography for Assessing Liver Fibrosis in Chronic Hepatitis B

2017 ◽  
Vol 43 (8) ◽  
pp. 1563-1570 ◽  
Author(s):  
Jie Zeng ◽  
Jian Zheng ◽  
Zeping Huang ◽  
Shigao Chen ◽  
Jing Liu ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Shear Wave ◽  
Chronic Hepatitis B ◽  
Transient Elastography ◽  
Shear Wave Elastography

scholarly journals The Evaluation of Liver Fibrosis in the Real-Time Shear Wave Elastography Technique in Chronic Hepatitis B and C Patients: How Many Measurements Are Necessary to Assign Patients to METAVIR Score Properly?

2018 ◽  
Vol 18 (6) ◽  
Author(s):  
Urszula Zaleska-Dorobisz ◽  
Marcin Inglot ◽  
Aleksander Pawlus ◽  
Mateusz Patyk ◽  
Bartosz Dariusz Markiewicz ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Liver Fibrosis ◽  
Hepatitis B ◽  
Real Time ◽  
Shear Wave ◽  
Chronic Hepatitis B ◽  
Shear Wave Elastography ◽  
The Real ◽  
Metavir Score
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