Platycodin D is a potent adjuvant of specific cellular and humoral immune responses against recombinant hepatitis B antigen

Vaccine ◽  
2009 ◽  
Vol 27 (5) ◽  
pp. 757-764 ◽  
Author(s):  
Yong Xie ◽  
Hong-Xiang Sun ◽  
Duo Li
Keyword(s):  
Hepatitis B ◽  
Immune Responses ◽  
Recombinant Hepatitis ◽  
Humoral Immune ◽  
Platycodin D ◽  
Humoral Immune Responses ◽  
Hepatitis B Antigen

Potent enhancement of cellular and humoral immune responses against recombinant hepatitis B antigens using AS02A adjuvant in healthy adults

Vaccine ◽  
2005 ◽  
Vol 23 (20) ◽  
pp. 2591-2601 ◽  
Author(s):  
Pierre Vandepapelière ◽  
Barbara Rehermann ◽  
Marguerite Koutsoukos ◽  
Philippe Moris ◽  
Nathalie Garçon ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Immune Responses ◽  
Healthy Adults ◽  
Recombinant Hepatitis ◽  
Humoral Immune ◽  
Humoral Immune Responses ◽  
Hepatitis B Antigens

Comparison of humoral and cell-mediated immune responses to cationic PLGA microspheres containing recombinant hepatitis B antigen

2011 ◽  
Vol 408 (1-2) ◽  
pp. 50-57 ◽  
Author(s):  
Vinay Saini ◽  
Vikas Jain ◽  
M.S. Sudheesh ◽  
K.S. Jaganathan ◽  
P.K. Murthy ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Immune Responses ◽  
Plga Microspheres ◽  
Recombinant Hepatitis ◽  
Hepatitis B Antigen

scholarly journals A Recombinant Measles Virus Expressing Hepatitis B Virus Surface Antigen Induces Humoral Immune Responses in Genetically Modified Mice

1999 ◽  
Vol 73 (6) ◽  
pp. 4823-4828 ◽  
Author(s):  
Mahender Singh ◽  
Roberto Cattaneo ◽  
Martin A. Billeter
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Immune Responses ◽  
Surface Antigen ◽  
Measles Virus ◽  
Genetically Modified ◽  
Humoral Immune ◽  
Humoral Immune Responses ◽  
B Virus ◽  
Genetically Modified Mice

ABSTRACT It has been shown previously that measles virus (MV) can be successfully used to express foreign proteins (M. Singh and M. A. Billeter, J. Gen. Virol. 80:101–106, 1998). To develop an inexpensive MV-based vaccine, we generated recombinant MVs that produce structural proteins of hepatitis B virus (HBV). A recombinant virus that expressed the HBV small surface antigen (HBsAg) was analyzed in terms of its replication characteristics, its genetic stability in cell culture, and its immunogenic potential in genetically modified mice. Although this virus showed a progression of replication slightly slower than that of the parental MV, it appeared to stably maintain the added genetic information; it uniformly expressed the appropriately glycosylated HBsAg after 10 serial passages. Genetically modified mice inoculated with this recombinant MV produced humoral immune responses against both HBsAg and MV proteins.

Humoral immune responses in mice using gamma inulin preparations as adjuvants for hepatitis B vaccines

1990 ◽  
Vol 68 (2) ◽  
pp. 107-112 ◽  
Author(s):  
D. E. Leslie ◽  
S. Nicholson ◽  
M. Dimitrakakis ◽  
N. Johnston ◽  
I. D. Gust
Keyword(s):  
Hepatitis B ◽  
Immune Responses ◽  
Humoral Immune ◽  
Humoral Immune Responses ◽  
Hepatitis B Vaccines
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