Protective immune response in BALB/c mice induced by a suicidal DNA vaccine of the MIC3 gene of Toxoplasma gondii

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pp. 134-140 ◽  
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Hao Nie ◽  
Zhengsong Wang ◽  
Pan Tu ◽  
Danna Zhou ◽  
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Acta Tropica ◽  
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Vol 166 ◽  
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Yue Hu ◽  
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Fangjun Luo ◽  
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Yee Ling Lau ◽  
Kalyanasundaram Ramaswamy ◽  
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Vaccine ◽  
2012 ◽  
Vol 30 (10) ◽  
pp. 1800-1806 ◽  
Author(s):  
Huaiyu Zhou ◽  
Juan Min ◽  
Qunli Zhao ◽  
Qinmin Gu ◽  
Hua Cong ◽  
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Alexandro Rodriguez ◽  
Judith Molina ◽  
Jaline C. Silvério ◽  
Ana P. M. P. Marino ◽  
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ABSTRACT Immunization of BALB/c mice with an expression genomic library of Toxoplasma gondii induces a Th1-type immune response, with recognition of several T. gondii proteins (21 to 117 kDa) and long-term protective immunity against a lethal challenge. These results support further investigations to achieve a multicomponent anti-T. gondii DNA vaccine.


Vaccine ◽  
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Vol 194 (2-4) ◽  
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Yaping Yang ◽  
Xiaodi Yang ◽  
Yuan Gu ◽  
Yunyun Wang ◽  
Xi Zhao ◽  
...  

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