scholarly journals A Prediction Method for P-glycoprotein–Mediated Drug–Drug Interactions at the Human Blood–Brain Barrier From Blood Concentration–Time Profiles, Validated With PET Data

2017 ◽  
Vol 106 (9) ◽  
pp. 2780-2786 ◽  
Author(s):  
Akihiro Matsuda ◽  
Rudolf Karch ◽  
Martin Bauer ◽  
Alexander Traxl ◽  
Markus Zeitlinger ◽  
...  
Keyword(s):  
Drug Interactions ◽  
Blood Brain Barrier ◽  
Human Blood ◽  
Blood Concentration ◽  
Prediction Method ◽  
Brain Barrier ◽  
Time Profiles ◽  
Concentration Time ◽  
P Glycoprotein ◽  
Blood Brain

Regulation of BCRP (ABCG2) and P-Glycoprotein (ABCB1) by Cytokines in a Model of the Human Blood–Brain Barrier

2009 ◽  
Vol 30 (1) ◽  
pp. 63-70 ◽  
Author(s):  
Birk Poller ◽  
Jürgen Drewe ◽  
Stephan Krähenbühl ◽  
Jörg Huwyler ◽  
Heike Gutmann
Keyword(s):  
Blood Brain Barrier ◽  
Human Blood ◽  
Brain Barrier ◽  
P Glycoprotein ◽  
Blood Brain

Rapid assessment of p-glycoprotein–drug interactions at the blood–brain barrier

2006 ◽  
Vol 358 (1) ◽  
pp. 51-58 ◽  
Author(s):  
Martin Bubik ◽  
Melanie Ott ◽  
Anne Mahringer ◽  
Gert Fricker
Keyword(s):  
Drug Interactions ◽  
Blood Brain Barrier ◽  
Rapid Assessment ◽  
Brain Barrier ◽  
P Glycoprotein ◽  
Blood Brain

scholarly journals Factors Governing P-Glycoprotein-Mediated Drug–Drug Interactions at the Blood–Brain Barrier Measured with Positron Emission Tomography

2015 ◽  
Vol 12 (9) ◽  
pp. 3214-3225 ◽  
Author(s):  
Thomas Wanek ◽  
Kerstin Römermann ◽  
Severin Mairinger ◽  
Johann Stanek ◽  
Michael Sauberer ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Drug Interactions ◽  
Blood Brain Barrier ◽  
Emission Tomography ◽  
Brain Barrier ◽  
P Glycoprotein ◽  
Blood Brain ◽  
Positron Emission

Temozolomide down-regulates P-glycoprotein in human blood–brain barrier cells by disrupting Wnt3 signaling

2013 ◽  
Vol 71 (3) ◽  
pp. 499-516 ◽  
Author(s):  
Chiara Riganti ◽  
Iris C. Salaroglio ◽  
Martha L. Pinzòn-Daza ◽  
Valentina Caldera ◽  
Ivana Campia ◽  
...  
Keyword(s):  
Blood Brain Barrier ◽  
Human Blood ◽  
Brain Barrier ◽  
P Glycoprotein ◽  
Blood Brain

Dual inhibitors of the human blood-brain barrier drug efflux transporters P-glycoprotein and ABCG2 based on the antiviral azidothymidine

2017 ◽  
Vol 25 (19) ◽  
pp. 5128-5132 ◽  
Author(s):  
Hilda A. Namanja-Magliano ◽  
Kelsey Bohn ◽  
Neha Agrawal ◽  
Meghan E. Willoughby ◽  
Christine A. Hrycyna ◽  
...  
Keyword(s):  
Blood Brain Barrier ◽  
Human Blood ◽  
Brain Barrier ◽  
Efflux Transporters ◽  
Drug Efflux ◽  
P Glycoprotein ◽  
Blood Brain ◽  
Dual Inhibitors ◽  
Drug Efflux Transporters

Retrospective Analysis of P-Glycoprotein–Mediated Drug-Drug Interactions at the Blood-Brain Barrier in Humans

2013 ◽  
Vol 41 (4) ◽  
pp. 683-688 ◽  
Author(s):  
Hiroshi Sugimoto ◽  
Hideki Hirabayashi ◽  
Nobuyuki Amano ◽  
Toshiya Moriwaki
Keyword(s):  
Drug Interactions ◽  
Retrospective Analysis ◽  
Blood Brain Barrier ◽  
Brain Barrier ◽  
P Glycoprotein ◽  
Blood Brain

scholarly journals The ontogeny of P-glycoprotein in the developing human blood–brain barrier: implication for opioid toxicity in neonates

2015 ◽  
Vol 78 (4) ◽  
pp. 417-421 ◽  
Author(s):  
Jessica Lam ◽  
Stephanie Baello ◽  
Majid Iqbal ◽  
Lauren E. Kelly ◽  
Patrick T. Shannon ◽  
...  
Keyword(s):  
Blood Brain Barrier ◽  
Human Blood ◽  
Brain Barrier ◽  
P Glycoprotein ◽  
Blood Brain
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