Impact of patient comorbidities on quality of life in patients who undergo surgery with sentinel lymph node biopsy for endometrial cancer

2020 ◽  
Vol 159 ◽  
pp. 209-210
Author(s):  
G. Dinoi ◽  
A.L. Weaver ◽  
M.E. McGree ◽  
S.C. Dowdy ◽  
K.J. Yost ◽  
...  
2015 ◽  
Vol 25 (1) ◽  
pp. 166-173 ◽  
Author(s):  
Marta Novackova ◽  
Michael J. Halaska ◽  
Helena Robova ◽  
Ivana Mala ◽  
Marek Pluta ◽  
...  

ObjectiveThe aim of this study was to prospectively monitor the patients’ quality of life (QoL) after vulvar cancer surgery.DesignThe design was prospective clinical study.SettingThe study was set in the Department of Obstetrics and Gynecology, 2nd Medical Faculty of the Charles University and University Hospital Motol, Prague, Czech Republic.MethodsA group of 36 patients underwent vulvar cancer surgery: 24 patients were subject to inguinofemoral lymphadenectomy (RAD) and 12 to sentinel lymph node biopsy. To evaluate QoL, the European Organisation for Research and Treatment of Cancer, QoL questionnaires (QLQ-C30 and QLQ-CX24) were administered to patients before and 6 and 12 months after surgery.ResultsIn patients with vulvar cancer after inguinofemoral lymphadenectomy, increased fatigue and impaired lymphedema were observed. In the group of patients after sentinel lymph node biopsy, none of the QoL variables worsened postoperatively. Comparing both groups 12 months after surgery, the RAD group had significantly worse outcomes in body image and cognitive functioning than the sentinel lymph node biopsy group.Patients in the RAD group, who received adjuvant radiotherapy (n = 13), had worse QoL in symptom experience (P < 0.05) at 6 and 12 months after the surgery than patients without radiotherapy (n = 11).ConclusionsLess radical surgery showed objectively better QoL results.


2004 ◽  
Vol 30 (7) ◽  
pp. 728-734 ◽  
Author(s):  
G Dubernard ◽  
L Sideris ◽  
S Delaloge ◽  
H Marsiglia ◽  
F Rochard ◽  
...  

2010 ◽  
Vol 16 (5) ◽  
pp. 555-557 ◽  
Author(s):  
Maryam Al Nakib ◽  
Max Buttarelli ◽  
Laetitia Huiart ◽  
Marc Martino ◽  
Carole Tarpin ◽  
...  

Author(s):  
Marco Roberto Seferin ◽  
Fábio Roberto Pinto ◽  
Ana Kober Nogueira Leite ◽  
Rogerio Aparecido Dedivitis ◽  
Marco Aurélio Vamondes Kulcsar ◽  
...  

2021 ◽  
Vol 10 (7) ◽  
pp. 1339
Author(s):  
Magdalena Tarkowska ◽  
Iwona Głowacka-Mrotek ◽  
Tomasz Nowikiewicz ◽  
Aleksander Goch ◽  
Wojciech Zegarski

The aim of this study was to evaluate the quality of life of patients undergoing surgical treatment of breast cancer depending on the type of procedure involving the breast (mastectomy vs. breast conserving treatment) and axillary fossa (sentinel lymph node biopsy vs. axillary lymph node dissection). The prospective study was carried out in a group of 338 females undergoing breast cancer treatment. Study variables were assessed by means of a diagnostic survey using standardized QLQ C30 and BR23 questionnaires as well as the Acceptance of Illness Scale and Mini-MAC scales. The quality of life was assessed at threetime points: on the day before the surgical procedure (I assessment) as well as three and 12 months after surgery (II and III assessment). Statistically significant differences between study groups were observed in the overall quality of life subscale (I, II, III—p < 0.0001), physical functioning (I—p < 0.0001; II—p = 0.0413; III—p < 0.0001), role functioning (I—p = 0.0002; III—p < 0.0001), emotional functioning (III—p = 0.0082), cognitive functioning (I—p = 0.0112; III—p < 0.0001), social functioning (III—p < 0.0001), body image (I, II, III—p < 0.0001), and sexual functioning (I—p = 0.0233; III—p = 0.0011). In most symptomatic scales, significant (p < 0.05) differences were also noted. Mastectomy and limfadenectomy patients were significantly (p < 0.0001) more prone to present with destructive coping strategies one year after surgery. Breast conserving therapy is associated with better quality of life outcomes as compared to mastectomy. Sentinel lymph node biopsy is associated with a lower intensity of adverse changes in multiple dimensions of patients’ functioning.


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