Ethylmalonic acid impairs brain mitochondrial succinate and malate transport

2012 ◽  
Vol 105 (1) ◽  
pp. 84-90 ◽  
Author(s):  
Alexandre Umpierrez Amaral ◽  
Cristiane Cecatto ◽  
Estela Natasha Brandt Busanello ◽  
César Augusto João Ribeiro ◽  
Daniela Rodrigues Melo ◽  
...  
Keyword(s):  
Ethylmalonic Acid ◽  
Malate Transport

Taurine, glutamic acid and ethylmalonic acid as important metabolites for detecting human breast cancer based on the targeted metabolomics

2018 ◽  
Vol 23 (2) ◽  
pp. 255-268 ◽  
Author(s):  
Xinyang Wang ◽  
Xinshu Zhao ◽  
Jing Chou ◽  
Jiaying Yu ◽  
Tongshu Yang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Glutamic Acid ◽  
Human Breast Cancer ◽  
Human Breast ◽  
Targeted Metabolomics ◽  
Ethylmalonic Acid

scholarly journals Pyruvate and Malate Transport and Oxidation in Corn Mitochondria

1977 ◽  
Vol 59 (4) ◽  
pp. 630-635 ◽  
Author(s):  
David A. Day ◽  
John B. Hanson
Keyword(s):  
Malate Transport

Conformational and enantiotropic polymorphism of a 1 : 1 cocrystal involving ethenzamide and ethylmalonic acid

CrystEngComm ◽  
2010 ◽  
Vol 12 (11) ◽  
pp. 3691 ◽  
Author(s):  
Srinivasulu Aitipamula ◽  
Pui Shan Chow ◽  
Reginald B. H. Tan
Keyword(s):  
Ethylmalonic Acid

scholarly journals Identification with a photoaffinity reagent of a tonoplast protein involved in vacuolar malate transport of Catharanthus roseus

1996 ◽  
Vol 9 (6) ◽  
pp. 799-808 ◽  
Author(s):  
Karim Lahjouji ◽  
Antoine Carrasco ◽  
Huguette Bouyssou ◽  
Louis Cazaux ◽  
Gerard Marigo ◽  
...  
Keyword(s):  
Catharanthus Roseus ◽  
Malate Transport

L-Malate transport and proton symport in vesicles prepared from Pseudomonas putida

1986 ◽  
Vol 64 (11) ◽  
pp. 1190-1194 ◽  
Author(s):  
F. R. Agbanyo ◽  
G. Moses ◽  
N. F. Taylor
Keyword(s):  
Membrane Potential ◽  
Pseudomonas Putida ◽  
Kinetic Analysis ◽  
Transport System ◽  
Electron Donor ◽  
Proton Transport ◽  
Proton Motive Force ◽  
Alkaline Ph ◽  
Proton Symport ◽  
Malate Transport

In vesicles from glucose-grown Pseudomonas putida, L-malate is transported by nonspecific physical diffusion. L-Malate also acts as an electron donor and generates a proton motive force (Δp) of 129 mV which is composed of a membrane potential (Δψ) of 60 mV and a ΔpH of 69 mV. In contrast, vesicles from succinate-grown cells (a) transport L-malate by a carrier-mediated system with a Km value of 14.3 mM and a Vmax of 313 nmol∙mg protein−1∙min−1, (b) generate no Δψ, ΔpH, or Δp when L-malate is the electron donor, and (c) produce an extravesicular alkaline pH during the transport of L-malate. A kinetic analysis of this L-malate-induced proton transport gives a Km value of 16 mM and a Vmax of 667 nmol H+∙mg protein−1∙min−1. This corresponds to a H+/L-malate ratio of 2.1. The failure to generate a Δp in these vesicles is considered, therefore, to be consistent with the induction in succinate-grown cells of an electrogenic proton symport L-malate transport system.

Malate transport and vacuolar ion channels in CAM plants

1997 ◽  
Vol 48 (Special) ◽  
pp. 623-631 ◽  
Author(s):  
C. M. Cheffings ◽  
O. Pantoja ◽  
F. M. Ashcroft ◽  
J. A. C. Smith
Keyword(s):  
Ion Channels ◽  
Cam Plants ◽  
Malate Transport
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