HeartMate II left ventricular assist system: from concept to first clinical use

The HeartMate II™ Left Ventricular Assist System has been implanted in more than 26,000 patients and is the most widely used and studied durable mechanical circulatory support device in patients with advanced heart failure. The device is intended for use as bridge to transplantation in candidates at risk of imminent death from non-reversible left ventricular (LV) failure and for destination therapy for use in patients with end-stage LV failure. This chapter describes each component of the system, the mechanisms of the pump itself, the physiology of blood flow under different pump speeds and pressure gradients, and ways to prevent pump thrombus. In addition, the functions and interface of the System Controller and System Monitor are detailed, including the settings displayed on the monitor and the type of alarms provided, as well as their appearance on the interface. The chapter closes with a discussion of how a ramped-speed study using echocardiography and hemodynamic assessment can identify the pump speed that provides the desired level of cardiac support for each patient.

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The HeartMate II: Design and Development of a Fully Sealed Axial Flow Left Ventricular Assist System

Artificial Organs ◽

10.1046/j.1525-1594.2001.06770.x ◽

2001 ◽

Vol 25 (5) ◽

pp. 380-385 ◽

Cited By ~ 42

Author(s):

David J. Burke ◽

Edward Burke ◽

Farzad Parsaie ◽

Victor Poirier ◽

Kenneth Butler ◽

...

Keyword(s):

Axial Flow ◽

Left Ventricular ◽

Left Ventricular Assist System ◽

Design And Development ◽

Heartmate Ii ◽

Ventricular Assist ◽

Left Ventricular Assist

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No Electromagnetic Interference Occurred in a Patient with a HeartMate II Left Ventricular Assist System and a Subcutaneous Implantable Cardioverter-Defibrillator

Texas Heart Institute Journal ◽

10.14503/thij-14-4795 ◽

2016 ◽

Vol 43 (2) ◽

pp. 183-185 ◽

Cited By ~ 13

Author(s):

Ajay Sundara Raman ◽

Farshad Raissi Shabari ◽

Biswajit Kar ◽

Pranav Loyalka ◽

Ramesh Hariharan

Keyword(s):

Electromagnetic Interference ◽

Left Ventricular ◽

Ventricular Assist Devices ◽

Left Ventricular Assist Devices ◽

Left Ventricular Assist System ◽

Heartmate Ii ◽

Ventricular Assist ◽

Cardioverter Defibrillator ◽

Device Infection ◽

Left Ventricular Assist

The use of subcutaneous implantable cardioverter-defibrillators is a novel option for preventing arrhythmia-mediated cardiac death in patients who are at risk of endovascular-device infection or in whom venous access is difficult. However, the potential for electromagnetic interference between subcutaneous defibrillators and left ventricular assist devices is largely unknown. We report the case of a 24-year-old man in whom we observed no electromagnetic interference between a subcutaneous implanted cardioverter-defibrillator and a HeartMate II Left Ventricular Assist System, at 3 different pump speeds. To our knowledge, this is the first report of such findings in this circumstance.

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