Differential cellular regulation of the mitochondrial permeability transition in an in vitro model of 1,3-dinitrobenzene-induced encephalopathy

2000 ◽  
Vol 874 (2) ◽  
pp. 165-177 ◽  
Author(s):  
Ronald B Tjalkens ◽  
Megan M Ewing ◽  
Martin A Philbert
2004 ◽  
Vol 378 (1) ◽  
pp. 213-217 ◽  
Author(s):  
Vladimir GOGVADZE ◽  
John D. ROBERTSON ◽  
Mari ENOKSSON ◽  
Boris ZHIVOTOVSKY ◽  
Sten ORRENIUS

The mechanisms regulating mitochondrial outer-membrane permeabilization and the release of cytochrome c during apoptosis remain controversial. In the present study, we show in an in vitro model system that the release of cytochrome c may occur via moderate modulation of mitochondrial volume, irrespective of the mechanism leading to the mitochondrial swelling. In contrast with mitochondrial permeability transition-dependent release of cytochrome c, in the present study mitochondria remain intact and functionally active.


1998 ◽  
Vol 43 (1) ◽  
pp. 19-27
Author(s):  
J. B. A. Custodio ◽  
C. M. Palmeira ◽  
A. J. Moreno ◽  
K. B. Wallace

2011 ◽  
Vol 144 (1-3) ◽  
pp. 636-646 ◽  
Author(s):  
Rongsheng Su ◽  
Rongmei Wang ◽  
Huabin Cao ◽  
Jiaqiang Pan ◽  
Lijun Chen ◽  
...  

2005 ◽  
Vol 39 (7) ◽  
pp. 949-959 ◽  
Author(s):  
Vincent K.S. Tay ◽  
Audrey S. Wang ◽  
Koon Yeow Leow ◽  
Michie M.K. Ong ◽  
Kim Ping Wong ◽  
...  

2016 ◽  
Vol 428 (20) ◽  
pp. 4154-4167 ◽  
Author(s):  
Ivan Lebedev ◽  
Alice Nemajerova ◽  
Zachariah H. Foda ◽  
Maja Kornaj ◽  
Michael Tong ◽  
...  

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