This chapter examines a small number of recent graphic brain narratives that experiment with novel methods of visualizing the brain—including David B.’s Epileptic, Ellen Forney’s Marbles, and Matteo Farinella and Hana Ros’s Neurocomic. Tougaw argues that these narratives both draw from and challenge cultural responses to high-profile neuroimaging techniques, including PET and fMRI. Graphic narratives are a subcultural genre celebrated for their rebellious aesthetics and emphasis on narratives that challenge mainstream social and political assumptions. Brain scanning technologies are highly specialized tools that have revolutionized brain research and gained considerable mainstream attention. The mainstreaming of these technologies oversimplifies the images they produce, creating a widely held sense that they offer direct access to the brains they visualize. By contrast, graphic narratives put heavy emphasis on the aesthetic process involved in their making of brain images. While careful not to minimize these differences, the chapter argues that key similarities between neurocomics and neuroimaging techniques can be a means for clarifying the roles played by the sciences and the humanities in the cultural laboratory of contemporary neuromania.