Structure of the O-specific polysaccharide of Proteus mirabilis O11, another Proteus O-antigen containing an amide of d-galacturonic acid with l-threonine

1999 ◽  
Vol 323 (1-4) ◽  
pp. 81-86 ◽  
Author(s):  
Nikolay P Arbatsky ◽  
Alexander S Shashkov ◽  
Elzbieta Literacka ◽  
Göran Widmalm ◽  
Wieslaw Kaca ◽  
...  
Keyword(s):  
Proteus Mirabilis ◽  
Galacturonic Acid ◽  
O Antigen ◽  
Specific Polysaccharide

Structure and Epitope Characterisation of the O-specific Polysaccharide of Proteus mirabilis O28 Containing Amides of d-galacturonic Acid with l-serine and l-lysine

1995 ◽  
Vol 230 (2) ◽  
pp. 705-712 ◽  
Author(s):  
Joanna Radziejewska-Lebrecht ◽  
Alexander S. Shashkov ◽  
Eugeny V. Vinogradov ◽  
Horst Grosskurth ◽  
Beata Bartodziejska ◽  
...  
Keyword(s):  
Proteus Mirabilis ◽  
Galacturonic Acid ◽  
Specific Polysaccharide

Structural and serological studies of the O-antigen of Proteus mirabilis O-9

2003 ◽  
Vol 338 (11) ◽  
pp. 1191-1196 ◽  
Author(s):  
Anna N. Kondakova ◽  
Rafal Fudala ◽  
Sof'ya N. Senchenkova ◽  
Aleksander S. Shashkov ◽  
Yuriy A. Knirel ◽  
...  
Keyword(s):  
Proteus Mirabilis ◽  
O Antigen ◽  
Serological Studies

scholarly journals Structure of the O-specific polysaccharide of Proteus mirabilis D52 and typing of this strain to Proteus serogroup O33

2001 ◽  
Vol 268 (15) ◽  
pp. 4346-4351 ◽  
Author(s):  
Krystyna Zych ◽  
Filip V. Toukach ◽  
Nikolay P. Arbatsky ◽  
Katarzyna Kołodziejska ◽  
Sof'ya N. Senchenkova ◽  
...  
Keyword(s):  
Proteus Mirabilis ◽  
Specific Polysaccharide

Structural study and serological characterisation of the O-specific polysaccharide of Hafnia alvei PCM 1185, another Hafnia O-antigen that contains 3,6-dideoxy-3-[(R)-3-hydroxybutyramido]-d-glucose

1996 ◽  
Vol 293 (1) ◽  
pp. 61-70 ◽  
Author(s):  
Ewa Katzenellenbogen ◽  
Joanna Kübler ◽  
Andrzej Gamian ◽  
Elzbieta Romanowska ◽  
Aleksander S. Shashkov ◽  
...  
Keyword(s):  
Structural Study ◽  
Hafnia Alvei ◽  
O Antigen ◽  
Specific Polysaccharide

scholarly journals Structural and serological studies on the O-antigen of Proteus mirabilis O14, a new polysaccharide containing 2-[(R)-1-carboxyethylamino]ethyl phosphate

1999 ◽  
Vol 261 (2) ◽  
pp. 347-353 ◽  
Author(s):  
Andrei V. Perepelov ◽  
Elzbieta Ujazda ◽  
Sof'ya N. Senchenkova ◽  
Alexander S. Shashkov ◽  
Wieslaw Kaca ◽  
...  
Keyword(s):  
Proteus Mirabilis ◽  
O Antigen ◽  
Serological Studies ◽  
Ethyl Phosphate

scholarly journals The structure of Proteus mirabilis O3 O-specific polysaccharide containing N-(2-hydroxyethyl)-D-alanine

1990 ◽  
Vol 188 (3) ◽  
pp. 645-651 ◽  
Author(s):  
Evgeny V. VINOGRADOV ◽  
Wieslaw KACA ◽  
Alexander S. SHASHKOV ◽  
Danuta KRAJEWSKA-PIETRASIK ◽  
Antoni ROZALSKI ◽  
...  
Keyword(s):  
Proteus Mirabilis ◽  
Specific Polysaccharide

scholarly journals Loss of the WaaL O-Antigen Ligase Prevents Surface Activation of the Flagellar Gene Cascade in Proteus mirabilis

2010 ◽  
Vol 192 (12) ◽  
pp. 3213-3221 ◽  
Author(s):  
Randy M. Morgenstein ◽  
Katy M. Clemmer ◽  
Philip N. Rather
Keyword(s):  
Proteus Mirabilis ◽  
Lipid A ◽  
Response Regulator ◽  
Soft Agar ◽  
Solid Surfaces ◽  
Loss Of Function ◽  
Swarmer Cell ◽  
Gram Negative ◽  
O Antigen ◽  
Enterobacterial Common Antigen

ABSTRACT Proteus mirabilis is a Gram-negative bacterium that undergoes a physical and biochemical change from a vegetative swimmer cell (a typical Gram-negative rod) to an elongated swarmer cell when grown on a solid surface. In this study, we report that a transposon insertion in the waaL gene, encoding O-antigen ligase, blocked swarming motility on solid surfaces but had little effect on swimming motility in soft agar. The waaL mutant was unable to differentiate into a swarmer cell. Differentiation was also prevented by a mutation in wzz, encoding a chain length determinant for O antigen, but not by a mutation in wzyE, encoding an enzyme that polymerizes enterobacterial common antigen, a surface polysaccharide different from the lipid A::core. In wild-type P. mirabilis, increased expression of the flhDC operon occurs after growth on solid surfaces and is required for the high-level expression of flagellin that is characteristic of swarmer cells. However, in both the waaL and the wzz mutants, the flhDC operon was not activated during growth on agar. A loss-of-function mutation in the rcsB response regulator or overexpression of flhDC restored swarming to the waaL mutant, despite the absence of O antigen. Therefore, although O antigen may serve a role in swarming by promoting wettability, the loss of O antigen blocks a regulatory pathway that links surface contact with the upregulation of flhDC expression.

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