Cilostazol, a selective cAMP phosphodiesterase inhibitor, dilates retinal arterioles and increases retinal and choroidal blood flow in rats

1998 ◽  
Vol 344 (1) ◽  
pp. 49-52 ◽  
Author(s):  
Harumi Hotta ◽  
Hideki Ito ◽  
Fusako Kagitani ◽  
Akio Sato
Keyword(s):  
Blood Flow ◽  
Phosphodiesterase Inhibitor ◽  
Choroidal Blood Flow ◽  
Camp Phosphodiesterase ◽  
Retinal Arterioles

Stimulation of prostanoid IP and EP2 receptors dilates retinal arterioles and increases retinal and choroidal blood flow in rats

2007 ◽  
Vol 570 (1-3) ◽  
pp. 135-141 ◽  
Author(s):  
Asami Mori ◽  
Maki Saito ◽  
Kenji Sakamoto ◽  
Masami Narita ◽  
Tsutomu Nakahara ◽  
...  
Keyword(s):  
Blood Flow ◽  
Choroidal Blood Flow ◽  
Retinal Arterioles ◽  
Stimulation Of

Synergistic Antiplatelet Effect of Ridogrel, a Combined Thromboxane Receptor Antagonist and Thromboxane Synthase Inhibitor, and UDCG-212, a cAMP-Phosphodiesterase Inhibitor

1993 ◽  
Vol 70 (05) ◽  
pp. 822-825 ◽  
Author(s):  
B Hoet ◽  
J Arnout ◽  
H Deckmyn ◽  
J Vermylen
Keyword(s):  
Arachidonic Acid ◽  
Platelet Aggregation ◽  
Receptor Antagonist ◽  
Phosphodiesterase Inhibitor ◽  
Camp Phosphodiesterase ◽  
Thromboxane Receptor ◽  
Thromboxane Synthase Inhibitor ◽  
Thromboxane Receptor Antagonist ◽  
Synthase Inhibitor ◽  
Camp Levels

SummaryRidogrel, a combined thromboxane receptor antagonist and thromboxane synthase inhibitor (1), inhibits platelet aggregation. Following stimulation with arachidonic acid, cAMP-levels are increased in human platelets preincubated with ridogrel, this is due to the known reorientation of the metabolism of the formed endoperoxides towards adenylate cyclase stimulating prostaglandins.Pretreatment of resting platelets with UDCG-212, a cAMP-phosphodiesterase inhibitor (2), also inhibits platelet aggregation induced by arachidonic acid, concomitant with an increase in cAMP levels, due to an inhibition of its breakdown. Under basal conditions, cAMP also is increased.By combining the two drugs, a more than additive action was observed on platelet aggregation and on both resting and stimulated platelet cAMP content. The appropriate combination may result in a more effective antiplatelet strategy.

Choroidal Blood Flow

1982 ◽  
Vol 100 (8) ◽  
pp. 1327 ◽  
Author(s):  
Leonard M. Parver
Keyword(s):  
Blood Flow ◽  
Choroidal Blood Flow

Retinal and choroidal blood flow variations after an endurance exercise: A real-life pilot study at the Paris Marathon

2021 ◽  
Author(s):  
Martine Mauget-Faÿsse ◽  
Nicolas Arej ◽  
Morgane Paternoster ◽  
Kevin Zuber ◽  
Sabine Derrien ◽  
...  
Keyword(s):  
Blood Flow ◽  
Pilot Study ◽  
Endurance Exercise ◽  
Real Life ◽  
Choroidal Blood Flow

scholarly journals The Impact of Intraocular Pressure Elevation on Optic Nerve Head and Choroidal Blood Flow

2018 ◽  
Vol 59 (8) ◽  
pp. 3488 ◽  
Author(s):  
Naoki Kiyota ◽  
Yukihiro Shiga ◽  
Kohei Ichinohasama ◽  
Masayuki Yasuda ◽  
Naoko Aizawa ◽  
...  
Keyword(s):  
Blood Flow ◽  
Intraocular Pressure ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Choroidal Blood Flow ◽  
Pressure Elevation ◽  
Intraocular Pressure Elevation ◽  
The Impact

Inhaled Carbon Monoxide Increases Retinal and Choroidal Blood Flow in Healthy Humans

2005 ◽  
Vol 46 (11) ◽  
pp. 4275 ◽  
Author(s):  
Hemma Resch ◽  
Claudia Zawinka ◽  
Gu¨nther Weigert ◽  
Leopold Schmetterer ◽  
Gerhard Garho¨fer
Keyword(s):  
Carbon Monoxide ◽  
Blood Flow ◽  
Choroidal Blood Flow ◽  
Healthy Humans

scholarly journals Changes in Choroidal Blood Flow and Morphology in Response to Increase in Intraocular Pressure

2017 ◽  
Vol 58 (12) ◽  
pp. 5076 ◽  
Author(s):  
Tomohiko Akahori ◽  
Takeshi Iwase ◽  
Kentaro Yamamoto ◽  
Eimei Ra ◽  
Hiroko Terasaki
Keyword(s):  
Blood Flow ◽  
Intraocular Pressure ◽  
Choroidal Blood Flow

scholarly journals Defective Choroidal Blood Flow Baroregulation and Retinal Dysfunction and Pathology Following Sympathetic Denervation of Choroid

2018 ◽  
Vol 59 (12) ◽  
pp. 5032 ◽  
Author(s):  
Chunyan Li ◽  
Malinda E. C. Fitzgerald ◽  
Nobel Del Mar ◽  
Corey Haughey ◽  
Anton Reiner
Keyword(s):  
Blood Flow ◽  
Sympathetic Denervation ◽  
Choroidal Blood Flow ◽  
Retinal Dysfunction
Sign in / Sign up

Export Citation Format

Share Document