In vitro fertilization cycles converted to intrauterine insemination because of poor follicular response have low success rates

2001 ◽  
Vol 75 (3) ◽  
pp. 634-635 ◽  
Author(s):  
Naim Abusheikha ◽  
Amir Lass ◽  
Adam Burnley ◽  
Peter Brinsden
2005 ◽  
Vol 58 (7-8) ◽  
pp. 375-379 ◽  
Author(s):  
Dunja Tabs ◽  
Tihomir Vejnovic ◽  
Nebojsa Radunovic

Women conceiving by assisted reproduction are at higher risk for preterm and premature rupture of membranes. The aim of our study was to estimate and compare incidence of preterm premature rupture of membranes in singleton pregnancies of women who conceived by intrauterine insemination and in vitro fertilization, from 1999 to 2003. We investigated 87 women from the intrauterine insemination, and 102 from the in vitro fertilization program. There were no statistically significant differences in regard to preterm and premature rupture of membranes: p>0.75 in two groups. The incidence of premature rupture of membranes was 2.30% (after intrauterine insemination) and 2.94% (after in vitro fertilization). There was no statistically significant differences in regard to preterm and premature rupture of membranes in women who conceived by insemination and in vitro fertilization. Estimated incidence of preterm and premature rupture of membranes was similar to the literature data and also similar to incidence after natural conception.


2021 ◽  
Author(s):  
Cecilia Figoli ◽  
Marcelo Garcea ◽  
Claudio Bisioli ◽  
Valeria Tafintseva ◽  
Volha Shapaval ◽  
...  

Abstract The identification of the most competent embryos for transfer to the uterus constitutes the main challenge of in-vitro fertilization (IVF). We established a metabolomic-based approach applying Fourier Transform Infrared spectroscopy (FTIR) on 130 samples of 3-days embryo culture supernatants from 26 embryos that implanted and 104 that failed. Examining the internal structure of the data by unsupervised multivariate analysis, it was observed that the supernatants of nonimplanted embryos contained highly heterogeneous spectral features. These features were overlapping with metabolic-implantation fingerprints, thus demonstrating that in establishing embryo-assessment models a one-class modelling involving only the samples with positive-implantation outcomes should be applied. Analysis of variance confirmed that the women´s age (>40 years) undermined the implantation of the embryos exhibiting implantation metabolomics, and also that constituted a condition triggering embryos to express nonimplantation metabolomics. We conclude that IVF-success rates can be significantly improved if FTIR spectroscopy is used as an embryo-selection criterion.


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