Attitudes of in vitro fertilization and intrauterine insemination couples toward multiple gestation pregnancy and multifetal pregnancy reduction

Women conceiving by assisted reproduction are at higher risk for preterm and premature rupture of membranes. The aim of our study was to estimate and compare incidence of preterm premature rupture of membranes in singleton pregnancies of women who conceived by intrauterine insemination and in vitro fertilization, from 1999 to 2003. We investigated 87 women from the intrauterine insemination, and 102 from the in vitro fertilization program. There were no statistically significant differences in regard to preterm and premature rupture of membranes: p>0.75 in two groups. The incidence of premature rupture of membranes was 2.30% (after intrauterine insemination) and 2.94% (after in vitro fertilization). There was no statistically significant differences in regard to preterm and premature rupture of membranes in women who conceived by insemination and in vitro fertilization. Estimated incidence of preterm and premature rupture of membranes was similar to the literature data and also similar to incidence after natural conception.

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Chapter-06 Intrauterine Insemination and In Vitro Fertilization

Jaypee Gold Standard Mini Atlas Series� Infertility Management ◽

10.5005/jp/books/10418_6 ◽

2008 ◽

pp. 144-160

Author(s):

Sushma Deshmukh

Keyword(s):

In Vitro Fertilization ◽

Intrauterine Insemination ◽

Vitro Fertilization

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A Randomized Clinical Trial to Evaluate Optimal Treatment for Unexplained Infertility

50 Studies Every Obstetrician-Gynecologist Should Know ◽

10.1093/med/9780190947088.003.0045 ◽

2021 ◽

pp. 246-250

Author(s):

Stephanie Rothenberg ◽

Joseph Sanfilippo

Keyword(s):

Ovulation Induction ◽

Treatment Approach ◽

Intrauterine Insemination ◽

Clomiphene Citrate ◽

Unexplained Infertility ◽

Additional Benefit ◽

Multiple Gestation ◽

Time To Pregnancy ◽

Vitro Fertilization

The treatment of unexplained infertility has traditionally been comprised of a stepwise treatment approach, first with ovulation induction combined with intrauterine insemination (IUI) and then with in vitro fertilization (IVF). Ovulation induction is first attempted with clomiphene citrate, and, if unsuccessful, injectable gonadotropins are used. The value of ovulation induction with injectable gonadotropins in couples with unexplained infertility has been questioned, however, given the high risk of multiple gestation and the increasing efficacy of IVF. To address this, the FASTT trial randomized couples with unexplained infertility to a treatment arm that either included or omitted gonadotropin/IUI. They found that an accelerated treatment approach that involved 3 cycles of clomiphene citrate/IUI and then progressed immediately to IVF resulted in a decreased time to pregnancy compared to the group who underwent gonadotropin/IUI for 3 cycles, as well as decreased cost per live birth. Therefore, it was concluded that treatment of couples with unexplained infertility with gonadotropin/IUI was of no additional benefit.

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Stem Cells as a Resource for Treatment of Infertility-related Diseases

Current Molecular Medicine ◽

10.2174/1566524019666190709172636 ◽

2019 ◽

Vol 19 (8) ◽

pp. 539-546

Author(s):

Jing Wang ◽

Chi Liu ◽

Masayuki Fujino ◽

Guoqing Tong ◽

Qinxiu Zhang ◽

...

Keyword(s):

Stem Cells ◽

Stem Cell ◽

In Vitro Fertilization ◽

Cell Therapy ◽

Reproductive Medicine ◽

Intrauterine Insemination ◽

Reproductive Age ◽

Vitro Fertilization ◽

Undifferentiated Cells

Worldwide, infertility affects 8-12% of couples of reproductive age and has become a common problem. There are many ways to treat infertility, including medication, intrauterine insemination, and in vitro fertilization. In recent years, stem-cell therapy has raised new hope in the field of reproductive disability management. Stem cells are self-renewing, self-replicating undifferentiated cells that are capable of producing specialized cells under appropriate conditions. They exist throughout a human’s embryo, fetal, and adult stages and can proliferate into different cells. While many issues remain to be addressed concerning stem cells, stem cells have undeniably opened up new ways to treat infertility. In this review, we describe past, present, and future strategies for the use of stem cells in reproductive medicine.

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