Genetic Counseling in a Patient with XXY/XXXY/XY Mosaic Klinefelter’s Syndrome: Estimate of Sex Chromosome Aberrations in Sperm Before Intracytoplasmic Sperm Injection

1998 ◽  
Vol 69 (3) ◽  
pp. 482-485 ◽  
Author(s):  
Roland Kruse M.D. ◽  
Martina Guttenbach Ph.D. ◽  
Bettina Schartmann M.Sc. ◽  
Regine Schubert Ph.D. ◽  
Hans van der Ven M.D. ◽  
...  
Keyword(s):  
Genetic Counseling ◽  
Intracytoplasmic Sperm Injection ◽  
Chromosome Aberrations ◽  
Sex Chromosome ◽  
Klinefelter’S Syndrome ◽  
Klinefelter's Syndrome

Electroencephalographic Examination in the XYY Syndrome and in Klinefelter's Syndrome

1974 ◽  
Vol 125 (586) ◽  
pp. 236-237 ◽  
Author(s):  
Johannes Nielsen ◽  
Takayuki Tsuboi
Keyword(s):  
General Population ◽  
Chromosome Aberrations ◽  
Sex Chromosome ◽  
Klinefelter’S Syndrome ◽  
Klinefelter's Syndrome ◽  
Xyy Syndrome

Previous electroencephalographic studies of persons with sex chromosome aberrations have indicated that there might be more electroencephalographic aberrations in males with double Y and double X than in the general population. A survey of these studies has recently been made by Fenton et al. (1971).

Genetic Counseling in a Patient With XXY/XXXY/XY Mosaic Klinefelter's Syndrome

1998 ◽  
pp. 1943
Author(s):  
R. Kruse ◽  
M. Guttenbach ◽  
B. Schartmann ◽  
R. Schubert ◽  
H. van der Ven ◽  
...  
Keyword(s):  
Genetic Counseling ◽  
Klinefelter’S Syndrome ◽  
Klinefelter's Syndrome

scholarly journals Intracytoplasmic sperm injection outcome of ejaculated spermatozoa from a man with mosaic Klinefelter's Syndrome: case report and literature review

2018 ◽  
Vol 46 (10) ◽  
pp. 4323-4331 ◽  
Author(s):  
Yang Yu ◽  
Qi Xi ◽  
Jili Jing ◽  
Linlin Li ◽  
Hongguo Zhang ◽  
...  
Keyword(s):  
Literature Review ◽  
Intracytoplasmic Sperm Injection ◽  
Birth Rate ◽  
Live Birth Rate ◽  
Fertilization Rate ◽  
Klinefelter’S Syndrome ◽  
Klinefelter's Syndrome ◽  
Chromosome Pattern ◽  
Sperm Nuclei

Objective To report a case of abortion after intracytoplasmic sperm injection (ICSI) with ejaculated spermatozoa obtained from a man with mosaic Klinefelter’s syndrome. Methods Sperm nuclei from the patient were analyzed by fluorescence in situ hybridization, and the disomy frequencies for chromosome 18 and the sex chromosomes were determined. A literature review of the ICSI outcome of ejaculated sperm in patients with Klinefelter’s syndrome was also performed. Results A total of 108 spermatozoa nuclei were analyzed. Of these, 102 sperm cells were normal with an X18 (55.56%) or Y18 (38.89%) chromosome pattern. Three cells with XX18 (2.78%) and three cells with YY18 (2.78%) signals were detected. The fetus stopped developing in the eighth week. The karyotype determined by an analysis of the abortive tissue was 46, XY. The literature review identified a total of 12 patients who were analyzed in 11 reports. The fertilization rate was 80.9%, and the live birth rate per transfer was 71.4%. Conclusions ICSI with ejaculated spermatozoa from men with Klinefelter’s syndrome can lead to pregnancy, for which the risk of transmission of chromosomal aneuploidy is low.

Klinefelter's syndrome: an analysis of the origin of the additional sex chromosome using molecular probes

1988 ◽  
Vol 52 (2) ◽  
pp. 93-109 ◽  
Author(s):  
P. A. JACOBS ◽  
T. J. HASSOLD ◽  
E. WHITTINGTON ◽  
G. BUTLER ◽  
S. COLLYER ◽  
...  
Keyword(s):  
Sex Chromosome ◽  
Molecular Probes ◽  
Klinefelter’S Syndrome ◽  
Klinefelter's Syndrome
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