The international IBD genetics consortium confirms linkage of Crohn's disease to a locus on chromosome 16 (IBD1)

2000 ◽  
Vol 118 (4) ◽  
pp. A708 ◽  
Author(s):  
Juleen A. Cavanaugh
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Chromosome 16

scholarly journals Analysis of Australian Crohn's disease pedigrees refines the localization for susceptibility to inflammatory bowel disease on chromosome 16

1998 ◽  
Vol 62 (4) ◽  
pp. 291-298 ◽  
Author(s):  
J. A. CAVANAUGH ◽  
D. F. CALLEN ◽  
S. R. WILSON ◽  
P. M. STANFORD ◽  
M. E. SRAML ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Bowel Disease ◽  
Chromosome 16 ◽  
Inflammatory Bowel

Mapping of a susceptibility locus for Crohn's disease on chromosome 16

Nature ◽  
1996 ◽  
Vol 379 (6568) ◽  
pp. 821-823 ◽  
Author(s):  
Jean-Pierre Hugot ◽  
Pierre Laurent-Puig ◽  
Corine Gower-Rousseau ◽  
Jane M. Olson ◽  
John C. Lee ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Susceptibility Locus ◽  
Chromosome 16

scholarly journals Detection ofMycobacterium avium ss. Paratuberculosisin Blau Syndrome Tissues

2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
C. Thomas Dow ◽  
Jay L. E. Ellingson
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Clinical Findings ◽  
Innate Immune ◽  
Inflammatory Disorder ◽  
Blau Syndrome ◽  
Environmental Aspects ◽  
Chromosome 16 ◽  
Dna Evidence ◽  
Systemic Inflammatory Disease

Background and Aim of the Work. Blau syndrome is an inherited granulomatous inflammatory disorder with clinical findings of uveitis, arthritis, and dermatitis. Although rare, Blau syndrome shares features with the more common diseases sarcoidosis and Crohn's disease. The clinical findings of Blau syndrome are indistinguishable from juvenile sarcoidosis; the mutations of Blau syndrome are on the same gene of chromosome 16 (CARD15) that confers susceptibility to Crohn's disease. The product of this gene is part of the innate immune system.Mycobacterium avium ss. paratuberculosis(MAP) is the putative cause of Crohn's disease and has been implicated as a causative agent of sarcoidosis.Methods. Archival tissues of individuals with Blau syndrome were tested for the presence of MAP.Results. DNA evidence of MAP was detected in all of the tissues.Conclusions. This article finds that MAP is present in Blau syndrome tissue and postulates that it has a causal role. The presence of MAP in Blau syndrome—an autosomal dominant, systemic inflammatory disease—connects genetic and environmental aspects of “autoimmune” disease.

American families with Crohn's disease have strong evidence for linkage to chromosome 16 but not chromosome 12

1998 ◽  
Vol 115 (5) ◽  
pp. 1056-1061 ◽  
Author(s):  
S BRANT ◽  
Y FU ◽  
C FIELDS ◽  
R BALTAZAR ◽  
G RAVENHILL ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Strong Evidence ◽  
Chromosome 12 ◽  
Chromosome 16 ◽  
American Families

On-table endoscopy to define strictures and resection margins: experience from 178 operations for Crohn's disease using intraoperative endoscopy

2001 ◽  
Vol 3 (Supplement 2) ◽  
pp. 58-62
Author(s):  
G. Olaison ◽  
P. Andersson ◽  
P. Myrelid ◽  
K. Smedh ◽  
J. Soderholm ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Resection Margins ◽  
Intraoperative Endoscopy

MRI imaging of the effects of infliximab in perianal fistulizing Crohn's disease

2001 ◽  
Vol 120 (5) ◽  
pp. A68-A68
Author(s):  
G VANASSCHE ◽  
D VANBECKEVOORT ◽  
D BIELEN ◽  
G COREMANS ◽  
I AERDEN ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Mri Imaging
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