Concomitant Anxiety Disorder Predicts Failure of Symptom Response After H. pylori (HP) Eradication in Patients With Functional Dyspepsia (FD)

2012 ◽  
Vol 142 (5) ◽  
pp. S-470
Author(s):  
Justin C. Wu ◽  
Yawen Chan ◽  
Jessica Ching ◽  
Pui Kuan Cheong ◽  
Joseph J. Sung ◽  
...  
Keyword(s):  
Anxiety Disorder ◽  
Functional Dyspepsia ◽  
Symptom Response ◽  
H Pylori

Epigastric symptom response to low FODMAP dietary advice compared with standard dietetic advice in individuals with functional dyspepsia

2021 ◽  
Author(s):  
Heidi M. Staudacher ◽  
Amy N. Nevin ◽  
Christopher Duff ◽  
Bradley J. Kendall ◽  
Gerald J. Holtmann
Keyword(s):  
Functional Dyspepsia ◽  
Dietary Advice ◽  
Symptom Response

scholarly journals The Gastro-protective Effect of Ginger (Zingiber officinale Roscoe) in Helicobacter pylori Positive Functional Dyspepsia

2019 ◽  
Vol 9 (2) ◽  
pp. 321-324 ◽  
Author(s):  
Vahideh Ebrahimzadeh Attari ◽  
Mohammad Hosein Somi ◽  
Mohammad Asghari Jafarabadi ◽  
Alireza Ostadrahimi ◽  
Seyed-Yaghob Moaddab ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Helicobacter Pylori ◽  
Functional Dyspepsia ◽  
Zingiber Officinale ◽  
Complementary Therapy ◽  
Positive Functional ◽  
Before And After ◽  
Rome Iii ◽  
Ginger Powder ◽  
H Pylori

Purpose: The present study aimed to assess the effect of ginger (Zingiber officinale) powder supplementation on Helicobacter pylori eradication and improvement of dyspeptic symptoms in patients with H. pylori positive functional dyspepsia (FD). Methods: During this pilot study 15 patients with H. pylori positive FD received 3 g/d ginger powder as three 1-g tablets for 4-weeks. Dyspepsia symptoms were asked before and after the intervention using a questionnaire based on the Rome III criteria. H. pylori eradication was also assessed by a non-invasive stool antigen (HpSAg) test. Results: Ginger consumption accompanied by significant H. pylori eradication rate of 53.3% (P = 0.019) and the odds ratio (95% CI) was 8 (1.07 to 357.14). Moreover, our results showed significant changes in most of the dyspepsia symptoms after ginger supplementation. Conclusion: According to our findings, Z. officinale can be considered as a useful complementary therapy for FD. However, due to the small number of clinical trials in this area, further welldesigned clinical trials are needed to explicitly talk about its effectiveness especially about the eradication of H. pylori.

Resolution of H. pylori antrum, corpus or pan-gastritis does not induced heartburn in patients with functional dyspepsia

2001 ◽  
Vol 120 (5) ◽  
pp. A237-A238
Author(s):  
Nimish B. Vakil ◽  
Nicholas J. Talley ◽  
Elisabeth Bolling-Sternevald ◽  
Ola Junghard ◽  
Rolf Carlsson
Keyword(s):  
Functional Dyspepsia ◽  
H Pylori

scholarly journals Failure of a Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy of H. pylori Eradication in H. pylori-Infected Patients with Functional Dyspepsia

Gut and Liver ◽  
2011 ◽  
Vol 5 (4) ◽  
pp. 468-471 ◽  
Author(s):  
Su Jin Hong ◽  
In Kyung Sung ◽  
Jae Gyu Kim ◽  
Sang Woo Lee ◽  
Suck Chei Choi ◽  
...  
Keyword(s):  
Functional Dyspepsia ◽  
Controlled Study ◽  
Double Blind ◽  
Double Blind Placebo ◽  
H Pylori

scholarly journals Serum IgG antibodies against Helicobacter pylori low molecular weight antigens 50kDa, 30kDa and Urease A 26 kDa, along with vacuolating cytotoxin A are associated with the outcome of the infection

2020 ◽  
Vol 77 (4) ◽  
pp. 405-412
Author(s):  
Nebojsa Manojlovic ◽  
Ivana Tufegdzic ◽  
Elizabeta Ristanovic ◽  
Dubravko Bokonjic
Keyword(s):  
Gastric Cancer ◽  
Molecular Weight ◽  
Helicobacter Pylori ◽  
Functional Dyspepsia ◽  
Low Molecular Weight ◽  
Igg Antibodies ◽  
Vacuolating Cytotoxin ◽  
Specific Outcome ◽  
H Pylori ◽  
Topographic Distribution

Background/Aim. We designed and conducted this study due to the fact that results of the previous studies about seroreactivity to low-molecular-weight Helicobacter pylori antigens, cytotoxin-associated gene A (CagA), vacuolating cytotoxin A (VacA) in patients with gastric cancer and peptic ulcer were conflicting. Methods. The Western blot test was performed in 123 patients, 31 with gastric cancer, 31 with duodenal ulcer, 31 with gastric ulcer, 30 with gastritis and functional dyspepsia in order to determine IgG antibodies to H. pylori antigens (CagA, VacA, Heat shock protein 60kDa, Urease B 66 kDa, Flagellin 55kDa, 50kDa, 30 kDa, Urease A 26 kDa, 24 kDa). In this study we analyzed: seroreactivity to H. pylori antigens between group with functional dyspepsia and others; between grades of different histopathological parameters of inflammation of antral and corporal mucosa and between antrum-predominant gastritis and corpus-predominant gastritis + pangastritis groups. Results. It was shown that seropositivity to 50 kDa antigen could be used as a biomarker for functional dyspepsia, seropositivity to 30 kDa antigen for antrumpredominant gastritis and H. pylori colonization in the antrum, to UreaseA26 kDa antigen for pangastritis and corpus-predominant gastritis and degree of inflammation in the corpus. Seropositivity to VacA was the biomarker for gastric cancer and peptic ulcer taken together and inflammation of antral mucosa. Seropositivity to CagA was associated with more intensive inflammation of antral and corporal mucosa, Urease B66 kDa with inflammation of corpus mucosa, but neither of them with specific outcome of H. pylori infection and topographic distribution of gastric inflammation. Conclusion. Serum IgG antibodies to H. pylori antigens 50kDa, and VacA may represent useful biomarkers for the specific outcome of H. pylori infection, while serum antibodies to 30 kDa and UreaseA26 kDa antigens might be used as specific biomarkers for different topographic distribution of inflammation in gastric mucosa.

scholarly journals ASSOCIATION OF DUODENAL EOSINOPHILIC INFILTRATE WITH HELICOBACTER PYLORI INFECTION, BUT NOT WITH FUNCTIONAL DYSPEPSIA

2020 ◽  
Vol 57 (1) ◽  
pp. 74-78 ◽  
Author(s):  
Carine LEITE ◽  
Luiz Edmundo MAZZOLENI ◽  
Diego de Mendonça UCHOA ◽  
Juliana Araújo CASTANHO ◽  
Felipe MAZZOLENI ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Functional Dyspepsia ◽  
Eosinophil Count ◽  
Gastrointestinal Symptoms ◽  
Duodenal Mucosa ◽  
Helicobacter Pylori Infection ◽  
Eosinophilic Infiltrate ◽  
Urease Test ◽  
H Pylori

ABSTRACT BACKGROUND: The role of Helicobacter pylori infection on eosinophilic infiltration in duodenal mucosa is poorly studied. An increase in the number of eosinophils in duodenum has been associated with functional dyspepsia. OBJECTIVE: To evaluate the influence of H. pylori infection on duodenal eosinophil count and the role of eosinophilic infiltrate of duodenum in functional dyspepsia. METHODS: Positive and negative H. pylori individuals were included. Both functional dyspeptic patients according to Rome III criteria (cases) and individuals without gastrointestinal symptoms (controls) were enrolled. They were submitted to upper endoscopy and H. pylori infection was verified by gastric histopathology and urease test. Eosinophils in the duodenal mucosa were counted in five high-power fields, randomly selected on slides of endoscopic biopsies. RESULTS: Thirty-nine H. pylori positive (mean age 40.5 and 69.2% women) and 24 negative patients (mean age 37.3 and 75% women) were included. The influence of the infection was observed in the duodenal eosinophil count, which was higher in infected individuals: median 13.2 vs 8.1 in non-infected individuals (P=0.005). When we analyzed patients according to symptoms, cases - mean age 39.6; 71.4% women - and controls - mean age 38.7; 71.4% women - had similar duodenal eosinophil count: median 11.9 and 12.6 respectively (P=0.19). CONCLUSIONS: We did not demonstrate association of duodenal eosinophil count with functional dyspepsia but found association with H. pylori infection.

Symptoms in functional dyspepsia: Role of H. pylori infection and delayed gastric emptying

1998 ◽  
Vol 114 ◽  
pp. A821
Author(s):  
F. Perri ◽  
R. Clemente ◽  
V. Festa ◽  
M. Quitadamo ◽  
V. Annese ◽  
...  
Keyword(s):  
Gastric Emptying ◽  
Functional Dyspepsia ◽  
Delayed Gastric Emptying ◽  
H Pylori

P.02.16: Symptom Pattern in Functional Dyspepsia and Gastroesophageal Reflux Disease: Role of H. Pylori Infection

2017 ◽  
Vol 49 ◽  
pp. e143-e144
Author(s):  
R. Tavani ◽  
A.F. Ciccaglione ◽  
S. Cocciolillo ◽  
A. Sepe ◽  
M. Di Berardino ◽  
...  
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Functional Dyspepsia ◽  
Reflux Disease ◽  
Symptom Pattern ◽  
H Pylori

scholarly journals From Bench to Bedside to Bug: An Update of Clinically Relevant Advances in the Care of Persons withHelicobacter pyloriAssociated Diseases

2000 ◽  
Vol 14 (3) ◽  
pp. 188-198 ◽  
Author(s):  
N Chiba ◽  
ABR Thomson ◽  
P Sinclair
Keyword(s):  
Functional Dyspepsia ◽  
International Workshop ◽  
Symptom Relief ◽  
Subsequent Development ◽  
Noninvasive Test ◽  
Ulcer Disease ◽  
Intention To Treat ◽  
Bismuth Citrate ◽  
H Pylori ◽  
The One

In-depth meetings of the XIth International Workshop on Gastroduodenal Pathology andHelicobacter pyloriled to the presentation and discussion of extensive new data onH pyloriand its diseases. The mode of transmission ofH pyloriremains unclear, and it remains unknown why only a small proportion of infected individuals develop duodenal or gastric ulcer disease and even fewer develop gastric cancer. The role ofH pylorieradication in persons with uninvestigated dyspepsia remains controversial. New clinical trials ofH pyloritreatment show symptom relief and improvement in the quality of life of persons with functional dyspepsia, especially in those with ulcer-like or reflux-like dyspepsia. Clearly the move is toward symptom-based management of persons with dyspepsia, with fewer endoscopies being needed in the otherwise healthy young dyspeptic patients. It remains controversial whether eradicatingH pyloriin duodenal ulcer or functional dyspepsia increases the risk of subsequent development of gastroesophageal reflux disease. The one-week proton pump inhibitor-based triple regimens remain the gold standard ofH pyloritherapy, but some of the ranitidine bismuth citrate plus two antibiotic regimens also achieve an 80%H pylorieradication rate on an intention-to-treat basis. While the urea breath test remains the noninvasive test of choice, interesting new data are available on the use of stool antigen testing to diagnoseH pyloriinfection. The number ofH pylori-associated gastroduodenal diseases grows to include possible liver, vascular, immune and skin conditions.

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