Su1760 Role of NSAID-Induced Alterations in Intestinal Smooth Muscle Activity and Transit in Lower Gut Injury

2012 ◽  
Vol 142 (5) ◽  
pp. S-497
Author(s):  
Karen S. Uray ◽  
Elizabeth Dial ◽  
Tri M. Phan ◽  
Lenard M. Lichtenberger
Keyword(s):  
Smooth Muscle ◽  
Muscle Activity ◽  
Intestinal Smooth Muscle

Role of stat6 in hypercontractility of murine small intestinal smooth muscle induced by nematode infection

2001 ◽  
Vol 120 (5) ◽  
pp. A534-A534
Author(s):  
A ZHAO ◽  
D MULLOY ◽  
J URBANJR ◽  
W GAUSE ◽  
T SHEADONOHUE
Keyword(s):  
Smooth Muscle ◽  
Nematode Infection ◽  
Intestinal Smooth Muscle ◽  
Small Intestinal

Role of stat6 in hypercontractility of murine small intestinal smooth muscle induced by nematode infection

2001 ◽  
Vol 120 (5) ◽  
pp. A534 ◽  
Author(s):  
Aiping Zhao ◽  
Daniel P. Mulloy ◽  
Joseph F. Urban ◽  
William C. Gause ◽  
Terez Shea-Donohue
Keyword(s):  
Smooth Muscle ◽  
Nematode Infection ◽  
Intestinal Smooth Muscle ◽  
Small Intestinal

Role of inducible nitric oxide synthase in postoperative intestinal smooth muscle dysfunction in rodents

2000 ◽  
Vol 118 (2) ◽  
pp. 316-327 ◽  
Author(s):  
Jörg C. Kalff ◽  
Wolfgang H. Schraut ◽  
Timothy R. Billiar ◽  
Richard L. Simmons ◽  
Anthony J. Bauer
Keyword(s):  
Nitric Oxide ◽  
Smooth Muscle ◽  
Nitric Oxide Synthase ◽  
Inducible Nitric Oxide Synthase ◽  
Intestinal Smooth Muscle ◽  
Muscle Dysfunction ◽  
Oxide Synthase ◽  
Smooth Muscle Dysfunction ◽  
Inducible Nitric Oxide

The action of the ionophore ionomycin in guinea-pig intestinal smooth muscle

1983 ◽  
Vol 61 (5) ◽  
pp. 535-538 ◽  
Author(s):  
G. T. Bolger ◽  
C. R. Triggle ◽  
D. J. Triggle
Keyword(s):  
Smooth Muscle ◽  
Guinea Pig ◽  
Intestinal Smooth Muscle ◽  
Contraction Coupling ◽  
Longitudinal Smooth Muscle ◽  
A 23187 ◽  
Low Concentrations ◽  
Tissue Responses ◽  
Muscle Responses

The ionophore ionomycin produced concentration-dependent (5 × 10−9 to 5 × 10−6 M) contractions in guinea-pig ileal longitudinal smooth muscle. Responses were dependent on extracellular Ca2+, consistent with the known role of this Ca2+ source in supporting excitation–contraction coupling to a variety of stimulants in this tissue. Responses were insensitive to atropine (10−6 M) but were dependent upon extracellular Na+ and were completely blocked by low concentrations of the Ca2+-channel antagonists nicardipine. YC-93 (5 × 10−7 M), and D-600 (5 × 10−6 M). The behaviour of ionomycin is very similar to that shown by A 23187 in this tissue. Ionomycin, like A 23187, can apparently activate D-600 sensitive Ca2+ channels in the guinea-pig intestinal smooth muscle rather than simply translocating Ca2+EXT.

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