Water Exchange (WE) Significantly Raises Adenoma Detection Rate (ADR) Compared with Water Immersion (WI) and Air Insufflation (AI) - Pooled Data from Two Multi-Site Randomized Controlled Trials (RCT)

2017 ◽  
Vol 152 (5) ◽  
pp. S643-S644
Author(s):  
Felix W. Leung ◽  
Malcolm Koo ◽  
Sergio Cadoni ◽  
Premysl Falt ◽  
Yu-Hsi Hsieh ◽  
...  
Keyword(s):  
Randomized Controlled Trials ◽  
Detection Rate ◽  
Water Exchange ◽  
Water Immersion ◽  
Adenoma Detection Rate ◽  
Controlled Trials ◽  
Pooled Data ◽  
Randomized Controlled ◽  
Adenoma Detection ◽  
Air Insufflation

scholarly journals Nurse Participation in Colonoscopy Observation versus the Colonoscopist Alone for Polyp and Adenoma Detection: A Meta-Analysis of Randomized, Controlled Trials

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Lei Xu ◽  
Yu Zhang ◽  
Haojun Song ◽  
Weihong Wang ◽  
Sijie Zhang ◽  
...  
Keyword(s):  
Randomized Controlled Trials ◽  
Detection Rate ◽  
Meta Analysis ◽  
Research Question ◽  
Adenoma Detection Rate ◽  
Cochrane Library ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Adenoma Detection ◽  
Significant Difference

The role of nurse participation (NP) in colonoscopy observation for polyp and adenoma detection is unclear. This study aimed to evaluate whether nurse participation can improve polyp and adenoma detection.Patients and Methods. The PUBMED, EMBASE, and Cochrane Library databases were searched for randomized controlled trials (RCTs) published in English. The outcome measurements included (1) the polyp and adenoma detection rate (PDR and ADR); (2) the advanced lesions detection rate; and (3) the mean polyp and adenoma detection rate per colonoscopy.Results. Three RCTs with a total of 1676 patients were included. The pooled data showed a significantly higher ADR in the NP group than colonoscopist alone (CA) (45.7% versus 39.3%; RR 1.16; 95% CI, 1.04–1.30). And it showed no significant difference in the PDR and advanced lesions detection rate between the two groups (RR: 1.14, 95% CI: 0.95–1.37; RR: 1.35, 95% CI: 0.91–2.00; resp.).Conclusions. Nurse participation during a colonoscopy can improve the ADR, whereas no benefit for the PDR and advanced lesions detection rate was observed. All RCTs included in the meta-analysis had high risk of bias. Thus, there is a need for new research that uses sound methodology to definitively address the research question under study.

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