scholarly journals Liver Disease in Asymptomatic Carriers of Hepatitis B Antigen

1974 ◽  
Vol 66 (5) ◽  
pp. 1020-1028 ◽  
Author(s):  
Jerome B. Simon ◽  
Subhash K. Patel
Keyword(s):  
Liver Disease ◽  
Hepatitis B ◽  
Asymptomatic Carriers ◽  
Hepatitis B Antigen

Cell-mediated immune response to hepatitis B antigen in patients with liver disease

1974 ◽  
Vol 19 (7) ◽  
pp. 637-643 ◽  
Author(s):  
Marietta J. Gerber ◽  
Anan Phuangsab ◽  
Sudin B. V. Vittal ◽  
Demetrios Dourdourekas ◽  
Frederick Steigmann ◽  
...  
Keyword(s):  
Immune Response ◽  
Liver Disease ◽  
Hepatitis B ◽  
Cell Mediated Immune Response ◽  
Hepatitis B Antigen

DETECTION OF HEPATITIS-B ANTIGEN BY RADIOIMMUNOASSAY IN CHRONIC LIVER DISEASE AND HEPATOCELLULAR CARCINOMA IN GREAT BRITAIN

The Lancet ◽  
1973 ◽  
Vol 302 (7831) ◽  
pp. 690-694 ◽  
Author(s):  
W.D. Reed ◽  
A.L.W.F. Eddleston ◽  
R.B. Stern ◽  
Roger Williams ◽  
A.J. Zuckerman ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Disease ◽  
Great Britain ◽  
Hepatitis B ◽  
Chronic Liver Disease ◽  
Chronic Liver ◽  
Hepatitis B Antigen

scholarly journals HBV-DNA, HBeAg/anti-HBe serological status in hepatitis B chronic individuals from central Italy

1990 ◽  
Vol 104 (3) ◽  
pp. 511-518 ◽  
Author(s):  
M. Rapicetta ◽  
V. Di Nardo ◽  
C. Rozera ◽  
G. Marinucci ◽  
D. Francisci ◽  
...  
Keyword(s):  
Liver Disease ◽  
Hepatitis B ◽  
Central Italy ◽  
Hbv Dna ◽  
Hbsag Carrier ◽  
Chronic Patients ◽  
Asymptomatic Carriers ◽  
Serological Status ◽  
Histological Activity ◽  
Normal Alt

SUMMARYA population of 488 HBsAg carrier individuals, from central Italy, classified on the basis of biochemical, clinical and histological parameters, was analysed for the presence of HBV-DNA in serum and its relationship with HBeAg/anti-HBe markers. The prevalence of HBV-DNA was 32·8% in chronic patients with biopsy-proven liver disease, and 20 and 4·3% respectively in asymptomatic carriers with and without altered ALT levels. The values in chronic patients were correlated with the histological activity.Concordance of HBV-DNA presence and HBeAg positivity was observed in only 61·4% of cases. However HBV-DNA prevalence in sera of anti-HBe positive individuals was very low in asymptomatic carriers with normal ALT levels (2·5%). Higher values were observed in anti-HBe positive chronic patients (15·8%) and in carriers occasionally found with changes in ALT without any other clinical sign of illness (16·7%). These data would indicate that HBV-DNA is the serological marker which is most closely related to liver disease.

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