scholarly journals Anti-inflammatory, Analgesic Properties and Antipyretic Action of 2-Amino-1,2,3,4-tetrahydroisoquinoline-1,3-dione and Its Derivatives.

1985 ◽  
Vol 39 ◽  
pp. 192
Author(s):  
Johji Yamahara ◽  
Hideki Murakami ◽  
Tokunosuke Sawada ◽  
Hajime Fujimura ◽  
Masao Okamoto
1987 ◽  
Vol 107 (1) ◽  
pp. 28-36 ◽  
Author(s):  
HIROMU KAWAKUBO ◽  
TAKANORI SONE ◽  
KOUICHI WAKIGAWA ◽  
TSUTOMU NARITA

1985 ◽  
Vol 105 (3) ◽  
pp. 249-255 ◽  
Author(s):  
JOHJI YAMAHARA ◽  
TOKUNOSUKE SAWADA ◽  
HAJIME FUJIMURA ◽  
MASAO OKAMOTO

2019 ◽  
Vol 70 (1) ◽  
pp. 248-253
Author(s):  
Gabi Topor ◽  
Aurel Nechita ◽  
Mihaela Debita ◽  
Corina Ciupilan ◽  
Elena Roxana Axente

Anti-inflammatory-analgesic medication is known to have a wide spread, its indications going beyond the area of rheumatology, aimed at various fields, cardiology, nephrology, hematology,neurology, etc. Many years of aspirin has constituted the health expectation of millions of patients. Most nonsteroidal anti-inflammatory analgesics (ASNS) are acidic compounds derived mainly from carboxylic acids and enolic acids. The non-acidic compounds are numerically reduced and relatively unrelated. The main effects of non-steroidal anti-inflammatory analgesics arise following antipyretic action, analgesic action and anti-immflamatory in varying proportions to each structural group. Each drug has the specificity of single actions, the global way of explaining the clinical effects remains little known. Anti-inflammatory (anti-termic) in acute rheumatism or other inflammatory joint disorders, anti-platelet antiaggregant, aspirin prevents aggregation of blood platelets (which have a role in stopping bleeding).This is why it is used to prevent thrombosis (clotting of blood in the arteries or veins) with an impOliant role in preventing myocardial infarction. The study includes 126 patients who often used aspirin. Interaction of aspirin with other drugs mainly occurs in the plasma albumin, platelets, liver, kidney and gastrointestinal tract. Considered a common drug, often used by patients without the physician�s indication, some of them under maintenance medication (corticosteroid, anticoagulants, antiplatelet, antidiabetics, cytostatics), aspirin may cause important complications.


1984 ◽  
Vol 15 (5-6) ◽  
pp. 606-611 ◽  
Author(s):  
Hideo Nakamura ◽  
Yuichi Yokoyama ◽  
Yasuhiro Seto ◽  
Toshiaki Kadokawa ◽  
Masanao Shimizu

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