scholarly journals Promotion of human platelet adhesion and aggregation by a synthetic, triple-helical “mini-collagen”.

1994 ◽  
Vol 269 (19) ◽  
pp. 13899-13903 ◽  
Author(s):  
G.H. Rao ◽  
C.G. Fields ◽  
J.G. White ◽  
G.B. Fields
Keyword(s):  
Platelet Adhesion ◽  
Human Platelet ◽  
Platelet Adhesion And Aggregation

A method for quantitative determination of flow induced human platelet adhesion and aggregation

1992 ◽  
Vol 67 (4) ◽  
pp. 407-418 ◽  
Author(s):  
Armin Tippe ◽  
Armin Reimnger ◽  
Cornelia Reininger ◽  
Regine Rieβ
Keyword(s):  
Quantitative Determination ◽  
Platelet Adhesion ◽  
Human Platelet ◽  
Platelet Adhesion And Aggregation

Lonomia obliqua venomous secretion induces human platelet adhesion and aggregation

2010 ◽  
Vol 30 (3) ◽  
pp. 300-310 ◽  
Author(s):  
Markus Berger ◽  
José Reck ◽  
Renata M. S. Terra ◽  
Walter O. Beys da Silva ◽  
Lucélia Santi ◽  
...  
Keyword(s):  
Platelet Adhesion ◽  
Human Platelet ◽  
Platelet Adhesion And Aggregation ◽  
Lonomia Obliqua

scholarly journals Microfluidic chip grafted with integrin tension sensors for evaluating the effects of flowing shear stress and ROCK inhibitor on platelets

Lab on a Chip ◽  
2021 ◽  
Author(s):  
Subin Mao ◽  
Anwesha Sarkar ◽  
Yongliang Wang ◽  
Chao Song ◽  
Dana Nicole LeVine ◽  
...  
Keyword(s):  
Shear Stress ◽  
Microfluidic Chip ◽  
Platelet Adhesion ◽  
Rock Inhibitor ◽  
Platelet Adhesion And Aggregation ◽  
Key Players

Integrins are key players in platelet adhesion and aggregation. Integrin molecular tensions, the forces transmitted by integrin molecules, are regulated by both mechanical and biochemical cues, and the outside-in and...

scholarly journals Glycoprotein Ibα–Mediated Platelet Adhesion and Aggregation to Immobilized Thrombin Under Conditions of Flow

2006 ◽  
Vol 26 (3) ◽  
pp. 670-675 ◽  
Author(s):  
Cees Weeterings ◽  
Jelle Adelmeijer ◽  
Timothy Myles ◽  
Philip G. de Groot ◽  
Ton Lisman
Keyword(s):  
Platelet Adhesion ◽  
Platelet Adhesion And Aggregation

Simulation of platelet adhesion and aggregation regulated by fibrinogen and von Willebrand factor

2008 ◽  
Vol 99 (01) ◽  
pp. 108-115 ◽  
Author(s):  
Koichiro Yano ◽  
Ken-ichi Tsubota ◽  
Takuji Ishikawa ◽  
Shigeo Wada ◽  
Takami Yamaguchi ◽  
...  
Keyword(s):  
Platelet Adhesion ◽  
Thrombus Formation ◽  
Simple Shear Flow ◽  
Stokesian Dynamics ◽  
General Observation ◽  
Significant Development ◽  
Platelet Adhesion And Aggregation ◽  
Von Willebrand ◽  
Willebrand Factor

SummaryWe propose a method to analyze platelet adhesion and aggregation computationally, taking into account the distinct properties of two plasma proteins, vonWillebrand factor (vWF) and fibrinogen (Fbg). In this method, the hydrodynamic interactions between platelet particles under simple shear flow were simulated using Stokesian dynamics based on the additivity of velocities. The binding force between particles mediated by vWF and Fbg was modeled using the Voigt model. Two Voigt models with different properties were introduced to consider the distinct behaviors of vWF and Fbg. Our results qualitatively agreed with the general observation of a previous in-vitro experiment, thus demonstrating that the significant development of thrombus formation in height requires not only vWF, but also Fbg. This agreement of simulation and experimental results qualitatively validates our model and suggests that consideration of the distinct roles of vWF and Fbg is essential to investigate the physiological and pathophysiological mechanisms of thrombus formation using a computational approach.

scholarly journals Platelet adhesion to decorin but not collagen I correlates with the integrin  2 dimorphism E534K, the basis of the human platelet alloantigen (HPA)-5 system

Haematologica ◽  
2011 ◽  
Vol 97 (5) ◽  
pp. 692-695 ◽  
Author(s):  
T. J. Kunicki ◽  
S. A. Williams ◽  
D. Diaz ◽  
R. W. Farndale ◽  
D. J. Nugent
Keyword(s):  
Platelet Adhesion ◽  
Human Platelet ◽  
Collagen I
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