A systematic review of vitamin D status and dietary intake in various Slovenian populations

Aim Vitamin D (VitD) is involved in calcium and phosphate homeostasis, bone health, and normal functioning of the immune system. VitD status is monitored using serum 25-hydroxy-vitamin D (25(OH)D) as a biomarker. Serum 25(OH)D concentrations below 30 nmol/L indicate VitD deficiency and below 50 nmol/L indicate insufficiency. VitD can be synthesised endogenously in human skin when exposed to ultraviolet B (UVB) radiation. In the absence of sufficient UVB-light exposure, VitD intake becomes the main source of VitD, with a recommended daily intake of 20 μg. The aim of this study was to conduct a review and meta-analysis on the abovementioned topics, focusing on scientific studies in various Slovenian populations. Methods We conducted a systematic review and meta-analysis of published scientific papers, academic theses, or conference contributions reporting serum 25(OH)D status and VitD intake across various Slovenian populations. A search was carried out using Web of Science, Scopus, Medline, and the Slovenian library database. Results We identified 43 pertinent studies that addressed 25(OH)D status and 16 that addressed VitD intake. Serum 25(OH)D status was generally low across all populations, and notable seasonal variability was observed. VitD intakes were below 5 μg in all studies. Conclusions A general observation is that various population groups across Slovenia are at high risk of vitamin D insufficiency and deficiency, particularly during wintertime. Regarding vitamin D intake, all included studies reported daily intakes below the recommended level. We also identified key research gaps that need to be addressed to support further public health decision-making.

MITIGASI BENCANA PERKAWINAN ANAK SEBAGAI UPAYA MEWUJUDKAN KELUARGA SAKINAH: PERSPEKTIF FIKIH PERLINDUNGAN ANAK

Child marriage, in the final analysis, is denial of childrens basic right. The practice also violates the prevailing law which sets a statutory age limitation for both men and women to marry at 19 years. The author seeks to analyse this legal-societal issue from Islamic law perspective. The analysis starts from the general observation that to prevent future dissent-disolvement of marriages, both parties should consider “rusyd”, in other words, their own or potential partners psychological, biological, and socio-economic maturity. In addition, to prevent child marriage, attention should be given to basic values of benefit (al mashlalah), the general principle of affection (mawaddah wa rahmah) and fulfillment of needs (taufir al-hajat).

A literature survey of nanomaterials for dye sensitised solar cells

This paper provides a survey of the advance in the literature of nanomaterials for dye sensitized solar cell. The survey highlights that most exploratory studies focus on variable nanomaterials the role of dye sensitized solar cell. The positive role of photoelectrochemical system fact, there are some methodological reservations about the outputs from these exploratory studies. A general observation from these studies is that the literature produced the antithetically results and there is no consensus neither on the existence.

Female Sexual Dysfunction in a Third Level Health Facility, Southern Nigeria

Background: Observation during our gynaecology consultations does not tend to agree with reviews in literature suggesting high prevalence of sexual dysfunction. With this background, we decided to subject this general observation to scientific scrutiny to determine the proportion of our patients that actually have sexual dysfunction; and thepredisposing risk factors. Objective: To determine the prevalence and risk factors associated with sexual dysfunction in females attending the gynaecology clinic of the University of Port Harcourt Teaching Hospital (UPTH), Port Harcourt. Methods: This was a prospective cross-sectional questionnaire based study of 72 females of reproductive age group attending the outpatient gynaecological unit of UPTH. They were interviewed using the Female Sexual Dysfunction Index (FSFI). A total FSFI score of less than 26.5 was indicative of sexual dysfunction. The data were collated and entered into SPSS version23 statistical software which was also used for analysis. A p-value of < 0.05 was considered significant. Results: The prevalence of sexual dysfunction in females was 61.1% using the FSFI of less than 26.50. The most common type of sexual dysfunction among the respondents was desire disorders (66.7%) followed by disorders of orgasm (62.5%), lubrication (56.9%), arousal (43.1%) and pain (40.3%). Advanced age, higher education, parity and female genital cutting were found to be associated with sexual dysfunction. Conclusion: The findings in this study showed that a significant number of women in our centre are affected with sexual dysfunction.

Nanoconfined methane flow behavior through realistic organic shale matrix under displacement pressure: a molecular simulation investigation

Academic investigations digging into the methane flow mechanisms at the nanoscale, closely related to development of shale gas reservoirs, had attracted tremendous interest in the past decade. At the same time, a good understanding of the complex essence remains challenging, while the broad theoretical scope, as well as application value, possesses great attraction. In this work, with the help of molecular dynamics methods nested in LAMMPS software, a fundamental framework is established to mimic the nanoconfined fluid flow through realistic organic shale matrix. Denoting evident discrepancy with existed contributions, shale matrix in this work is composed of specific number of kerogen molecules, rather than simple carbon-based nanotube. Recently, promotion efforts have been implemented in the academic community with the use of kerogen molecules, however, gas flow simulations are still lacking, and the pore shape in the current papers is always hypothesized as slit pores. The pore-geometry assumption seriously conflicts with the general observation phenomenon according to the advanced laboratory experiments, such as SEM image, AFM technology, that the organic pores tend to have circular pore geometry. In order to fill the knowledge gap, the circular nanopore with desirable pore size surrounded by kerogen molecules is constructed at first. The organic nanopore with various thermal maturity can be obtained by altering the kerogen molecular type, expecting to achieve more physically and theoretically similar to the realistic shale matrix. After that, methane flow simulation is performed by utilization of non-equilibrium molecular dynamics, the methane density as well as velocity distribution under different displacement pressures are depicted. Furthermore, detailed discussion with respect to the simulation results is provided. Results show that (a) displacement pressure acts as a dominant role affecting methane flow velocity and, however, fails to affect methane density distribution, a behavior mainly controlled by molecular–wall interactions; (b) the velocity distribution feature appears to be in line with the parabolic law under high atmosphere pressure, which can be attributed to small Knudsen number; (c) the simulation time will be prolonged with larger displacement pressure imposed on nanoconfined methane. Accordingly, this work can provide profound basis for accurate evaluation of nanoconfined gas flow behavior through shale matrix.

Development of Surgical and Visualization Procedures to Analyze Vasculatures by Mouse Tail Edema Model

Background Because of the high frequency of chronic edema formation in the current “aged” society, analyses and detailed observation of post-surgical edema are getting more required. Post-surgical examination of the dynamic vasculature including L.V. (Lymphatic Vasculature) to monitor edema formation has not been efficiently performed. Hence, procedures for investigating such vasculature are essential. By inserting transparent sheet into the cutaneous layer of mouse tails as a novel surgery model (theTailEdema bySilicone sheet mediatedTransparency protocol; TEST), the novel procedures are introduced and analyzed by series of histological analyses including video-based L.V. observation and 3D histological reconstruction of vasculatures in mouse tails. Results The dynamic generation of post-surgical main and fine (neo) L.V. connective structure during the edematous recovery process was visualized by series of studies with a novel surgery model. Snapshot images taken from live binocular image recording for TEST samples suggested the presence of main and elongating fine (neo) L.V. structure. After the ligation of L.V., the enlargement of main L.V. was confirmed. In the case of light sheet fluorescence microscopy (LSFM) observation, such L.V. connections were also suggested by using transparent 3D samples. Finally, the generation of neo blood vessels particularly in the region adjacent to the silicone sheet and the operated boundary region was suggested in 3D reconstruction images. However, direct detection of elongating fine (neo) L.V. was not suitable for analysis by such LSFM and 3D reconstruction procedures. Thus, such methods utilizing fixed tissues are appropriate for general observation for the operated region including of L.V. Conclusions The current surgical procedures and analysis on the post-surgical status are the first case to observe vasculatures in vivo with a transparent sheet. Systematic analyses including the FITC-dextran mediated snap shot images observation suggest the elongation of fine (neo) lymphatic vasculature. Post-surgical analyses including LSFM and 3D histological structural reconstruction, are suitable to reveal the fixed structures of blood and lymphatic vessels formation.

Experimental Study of the Effects of Changes in Arteriovenous Pressure Difference on the Survival Area of a Reverse Island Flap

In this article, the effect of the change of arteriovenous pressure on the survival area of reverse island flap was studied. The vein and saphenous artery in rabbits were selected to design the reverse island flap experimental model. Rabbits were divided into 4 groups: A: Control Group; B: Part anastomosis of the saphenous artery group; C: Part anastomosis of the vein group; and D: No superficial veins group. After surgery, for all four groups, flaps were assessed by general observation, radionuclide scans for the survival rate, and histology. We found that the survival rate of flaps in Group B was overtop than the other three groups (P < 0.05). The radioactive material (RM) in group B could be seen clearly, whereas the RM in Groups A, C, and D existed transiently. At ten days post-operation. Group B had more capillary regeneration and blood cells contrast to the other three groups. Increasing blood supply can improve the survival rate of flaps, but simply promoting venous return has no significant effect on improving the survival rate of flaps.

Physiological Effects of Neonicotinoid Insecticides on Non-Target Aquatic Animals—An Updated Review

In this paper, we review the effects of large-scale neonicotinoid contaminations in the aquatic environment on non-target aquatic invertebrate and vertebrate species. These aquatic species are the fauna widely exposed to environmental changes and chemical accumulation in bodies of water. Neonicotinoids are insecticides that target the nicotinic type acetylcholine receptors (nAChRs) in the central nervous systems (CNS) and are considered selective neurotoxins for insects. However, studies on their physiologic impacts and interactions with non-target species are limited. In researches dedicated to exploring physiologic and toxic outcomes of neonicotinoids, studies relating to the effects on vertebrate species represent a minority case compared to invertebrate species. For aquatic species, the known effects of neonicotinoids are described in the level of organismal, behavioral, genetic and physiologic toxicities. Toxicological studies were reported based on the environment of bodies of water, temperature, salinity and several other factors. There exists a knowledge gap on the relationship between toxicity outcomes to regulatory risk valuation. It has been a general observation among studies that neonicotinoid insecticides demonstrate significant toxicity to an extensive variety of invertebrates. Comprehensive analysis of data points to a generalization that field-realistic and laboratory exposures could result in different or non-comparable results in some cases. Aquatic invertebrates perform important roles in balancing a healthy ecosystem, thus rapid screening strategies are necessary to verify physiologic and toxicological impacts. So far, much of the studies describing field tests on non-target species are inadequate and in many cases, obsolete. Considering the current literature, this review addresses important information gaps relating to the impacts of neonicotinoids on the environment and spring forward policies, avoiding adverse biological and ecological effects on a range of non-target aquatic species which might further impair the whole of the aquatic ecological web.

Adherence to COVID-19 Mitigation Measures among Kilifi and Mombasa Residents - An Observational Study in Coastal Kenya

Aim: Corona Virus Disease-19 (COVID-19) pandemic led countries into engaging public health guidelines as a strategy towards preventing infections. Hand washing, social distancing and masking remains key measures for infection control and prevention of the COVID-19. Strict adherence to public health infection control and prevention protocols is necessary to contain the spread at the community stage of the virus. National and County governments in Kenya directed efforts and resources in implementing numerous infection control and prevention measures in public places and institutions. The study assessed adherence to water, sanitation and hygiene (WASH) guidelines among the residents of Kilifi and Mombasa County in combating COVID-19 infections. Methodology: A cross sectional study was conducted between 25th November and 4th December 2020 in ten sub-counties in Mombasa and Kilifi counties, Kenya. Data was collected using Open Data Kit (ODK) mobile application. Results: Forty observations were done in Kilifi (45 percent) and Mombasa (55.0 percent). More than a third (37.5 percent) of the observations were done at the household level, followed by public buildings (30.0 percent), market/shopping centers (30.0 percent) and bus terminus (2.5 percent). More than half of the occupants in both Kilifi 55.6 percent and Mombasa 68.2 percent observed physical distancing of 1.5 meters, however, low screening of temperature at the entrance was noted. The general observation shows only 55.6 percent of the premises visited had a hand-washing station in Kilifi while 68.2 percent in Mombasa County. Most of the hand washing stations had running water and people did proper handwashing in both Counties. Only 30.0 percent of the hand station at Kilifi County had soaps. Conclusion: COVID – 19 will continue to pose serious public health challenges as many premises still don’t adhere to some of the guidelines. Multi-sectoral feasible approaches towards ensuring further adherence on all the public health guidelines should be given priority to control and prevent COVID-19 infection

Facts and Myths about GM Food—The Case of Poland

The importance of biotechnology for the global economy is growing, including developments in the field of genetically modified organisms (GMO), which have revolutionized the cultivation of several major food crops. Despite the many benefits from introducing genetic modifications to crops, the Polish society shows a strong distrust towards GMO-based food. The negative attitude of the society towards genetically modified (GM) food could be considered irrational. It is not supported by adequate knowledge and is based on fears, despite the fact that there is no scientific evidence of threats of GM products towards the environment, health, or human life. Details of these perceptions were revealed within Polish society from surveys of three groups of respondents: consumers, students, farmers. Data from the surveys have been compared with the answers to the same questions by five biotechnology experts from Polish academic institutions. A general observation from the analysis of the survey results and past studies quoted in the literature review is that the level of understanding and acceptance of GMO technologies is still low in Polish society, and, to a large extent, is based on stereotypes rather than on scientific knowledge. They show broad support for the general benefits of GMOs, which does not vary between the three groups of respondents surveyed, but noticeably differs with the experts’ views. GMOs have allies, but also opponents who have their own beliefs shaped largely by unreliable information disseminated through the Internet and social media. Providing more reliable targeted information on GMOs based on scientific evidence can have an important role in changing polarized attitudes towards GM food.