Extraction of artemisinin and artemisinic acid from Artemisia annua L. using supercritical carbon dioxide

1997 ◽  
Vol 785 (1-2) ◽  
pp. 353-360 ◽  
Author(s):  
Marcel Kohler ◽  
Werner Haerdi ◽  
Philippe Christen ◽  
Jean-Luc Veuthey
Keyword(s):  
Carbon Dioxide ◽  
Supercritical Carbon Dioxide ◽  
Artemisia Annua ◽  
Artemisinic Acid ◽  
Artemisia Annua L ◽  
Supercritical Carbon

Global yield isotherms and kinetic of artemisinin extraction from Artemisia annua L leaves using supercritical carbon dioxide

2005 ◽  
Vol 36 (1) ◽  
pp. 40-48 ◽  
Author(s):  
Sócrates Quispe-Condori ◽  
Deny Sánchez ◽  
Mary A. Foglio ◽  
Paulo T.V. Rosa ◽  
Carsten Zetzl ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Supercritical Carbon Dioxide ◽  
Artemisia Annua ◽  
Artemisia Annua L ◽  
Supercritical Carbon

Techno-economic evaluation of artemisinin extraction from Artemisia annua L. using supercritical carbon dioxide

2019 ◽  
Vol 132 ◽  
pp. 336-343 ◽  
Author(s):  
Michelle F.F. Rodrigues ◽  
Ilza M.O. Sousa ◽  
Renata Vardanega ◽  
Gislaine C. Nogueira ◽  
M. Angela A. Meireles ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Economic Evaluation ◽  
Supercritical Carbon Dioxide ◽  
Artemisia Annua ◽  
Artemisia Annua L ◽  
Supercritical Carbon

scholarly journals Extraction of sweet wormwood (Artemisia annua L.) by supercritical carbon dioxide

2020 ◽  
pp. 22-36
Author(s):  
Senka Vidović ◽  
Siniša Simić ◽  
Aleksandra Gavarić ◽  
Milica Aćimović ◽  
Jelena Vladić
Keyword(s):  
Carbon Dioxide ◽  
Supercritical Carbon Dioxide ◽  
Supercritical Fluid Extraction ◽  
Supercritical Fluid ◽  
Artemisia Annua ◽  
Soxhlet Extraction ◽  
Fluid Extraction ◽  
Artemisia Annua L ◽  
Sweet Wormwood ◽  
Supercritical Carbon

In this study, supercritical carbon dioxide was applied for the extraction of Artemisia annua L. Moreover, the impact of different parameters of supercritical extraction on total yield was investigated and the obtained yields were compared to the ones obtained by conventional procedures, hydrodistillation and Soxhlet extraction. Supercritical fluid extraction at 40 °C and different pressures (100, 200, and 300 bar) resulted in extraction yields that were in the 2.23-5.18 % range, while the yields at 60 °C and the same pressures were in the range 2.43-3.35 %. The yields obtained by the Soxhlet extraction and hydrodistillation were 10.28 % and 0.10 %, respectively. Although supercritical fluid extraction is inferior to Soxhlet extraction in terms of the recovery of lipophilic components of A. annua, the Soxhlet extraction is not the method of choice for obtaining sweet wormwood extracts due to its numerous disadvantages that include the use of toxic solvents, extended extraction time, health safety of the product, the need for further processing, the impossibility of adjusting the selectivity and thus the composition of the product.

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