The Diagnosis and Treatment of Rheumatic Fever and Rheumatic Carditis

1958 ◽  
Vol 42 (5) ◽  
pp. 1343-1360 ◽  
Author(s):  
Benedict F. Massell
2006 ◽  
Vol 16 (2) ◽  
pp. 141-146 ◽  
Author(s):  
Tugcin Bora Polat ◽  
Yalim Yalcin ◽  
Celal Akdeniz ◽  
Cenap Zeybek ◽  
Abdullah Erdem ◽  
...  

Background:Disturbances of conduction are well known in the setting of acute rheumatic fever. The aim of this study is to investigate the QT dispersion as seen in the surface electrocardiogram of children with acute rheumatic fever.Methods:QT dispersion was quantitatively evaluated in 88 children with acute rheumatic fever. Patients were divided into two groups based on the absence or presence of carditis. As a control group, we studied 36 healthy children free of any disease, and matched for age with both groups. Repeat echocardiographic examinations were routinely scheduled in all patients at 3 months after the initial attack to study the evolution of valvar lesions.Results:The mean QT dispersion was significantly higher in children with rheumatic carditis. But there was no statistical difference between children without carditis and normal children. Among the children with carditis, the mean dispersion was higher in those with significant valvar regurgitation. Dispersion of greater than 55 milliseconds had a sensitivity of 85%, and specificity of 70%, in predicting rheumatic carditis, while a value of 65 milliseconds or greater had sensitivity of 81% specificity of 85% in predicting severe valvar lesions in acute rheumatic carditis. At follow-up examination, a clear reduction on the QT dispersion was the main finding, reflecting an electrophysiological improvement.Conclusions:These observations suggest that QT dispersion is increased in association with cardiac involvement in children with acute rheumatic fever.


1987 ◽  
Vol 51 (12) ◽  
pp. 1393-1396 ◽  
Author(s):  
YASUHISA KAJINO ◽  
HAJIME IWAYANI ◽  
NORIYUKI HANEDA ◽  
MASAKAZU SAITO ◽  
TOSHIKAZU NISHIO ◽  
...  

PEDIATRICS ◽  
1955 ◽  
Vol 15 (5) ◽  
pp. 537-542
Author(s):  
Rose Lubschez

1. The combined use of chromatographic separation of urinary 17-ketosteroid extracts on alumina columns and infra-red analysis of the fractions has permitted the identification of the major components in 5 mg. of a mixture of α ketosteroids. 2. In 4 non-rheumatic children, 4 rheumatic (inactive) children and 1 patient with active rheumatic carditis, the steroids identified in the urinary extracts were androsterone, Δ androstenolone, etiocholanolone and 11-keto etiocholanolone. Other steroids were present in insufficient quantity to be identified. 3. In 1 patient with active rheumatic carditis, the steroids excreted during an 8-day course of ACTH therapy were Δ androstenolone, etiocholanolone,11-hydroxy androsterone, 3 α, 11 β androstanediol-17-one, and 1 compound of possible clinical significance which has been reported by other investigators, the structural formula for which is not known. 4. There appears to be no inherent difference between the urinary ketosteroids of rheumatic (inactive) and non-rheumatic children.


PEDIATRICS ◽  
1970 ◽  
Vol 45 (5) ◽  
pp. 850-856
Author(s):  
Franco P. Stocker ◽  
Gabor Czoniczer ◽  
Benedict F. Massell ◽  
Alexander S. Nadas

A report is given of a 12-year-old Negro girl and her 14-year-old brother who presented with transient complete A-V block, reversible with atropine, during an attack of acute rheumatic fever with carditis.


Circulation ◽  
1996 ◽  
Vol 94 (1) ◽  
pp. 73-82 ◽  
Author(s):  
Ramachandran S. Vasan ◽  
Savitri Shrivastava ◽  
Manam Vijayakumar ◽  
Rajiv Narang ◽  
Bradford C. Lister ◽  
...  

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