Transient Complete A-V Block in Two Siblings During Acute Rheumatic Carditis in Childhood

PEDIATRICS ◽  
1970 ◽  
Vol 45 (5) ◽  
pp. 850-856
Author(s):  
Franco P. Stocker ◽  
Gabor Czoniczer ◽  
Benedict F. Massell ◽  
Alexander S. Nadas
Keyword(s):  
Rheumatic Fever ◽  
Acute Rheumatic Fever ◽  
Rheumatic Carditis ◽  
Negro Girl

A report is given of a 12-year-old Negro girl and her 14-year-old brother who presented with transient complete A-V block, reversible with atropine, during an attack of acute rheumatic fever with carditis.

QT dispersion in acute rheumatic fever

2006 ◽  
Vol 16 (2) ◽  
pp. 141-146 ◽  
Author(s):  
Tugcin Bora Polat ◽  
Yalim Yalcin ◽  
Celal Akdeniz ◽  
Cenap Zeybek ◽  
Abdullah Erdem ◽  
...  
Keyword(s):  
Rheumatic Fever ◽  
Acute Rheumatic Fever ◽  
Qt Dispersion ◽  
Control Group ◽  
Healthy Children ◽  
Rheumatic Carditis ◽  
Normal Children ◽  
A Value ◽  
The Mean

Background:Disturbances of conduction are well known in the setting of acute rheumatic fever. The aim of this study is to investigate the QT dispersion as seen in the surface electrocardiogram of children with acute rheumatic fever.Methods:QT dispersion was quantitatively evaluated in 88 children with acute rheumatic fever. Patients were divided into two groups based on the absence or presence of carditis. As a control group, we studied 36 healthy children free of any disease, and matched for age with both groups. Repeat echocardiographic examinations were routinely scheduled in all patients at 3 months after the initial attack to study the evolution of valvar lesions.Results:The mean QT dispersion was significantly higher in children with rheumatic carditis. But there was no statistical difference between children without carditis and normal children. Among the children with carditis, the mean dispersion was higher in those with significant valvar regurgitation. Dispersion of greater than 55 milliseconds had a sensitivity of 85%, and specificity of 70%, in predicting rheumatic carditis, while a value of 65 milliseconds or greater had sensitivity of 81% specificity of 85% in predicting severe valvar lesions in acute rheumatic carditis. At follow-up examination, a clear reduction on the QT dispersion was the main finding, reflecting an electrophysiological improvement.Conclusions:These observations suggest that QT dispersion is increased in association with cardiac involvement in children with acute rheumatic fever.

A case of acute rheumatic fever: Echocardiographic findings for mitral regurgitation in acute rheumatic carditis.

1987 ◽  
Vol 51 (12) ◽  
pp. 1393-1396 ◽  
Author(s):  
YASUHISA KAJINO ◽  
HAJIME IWAYANI ◽  
NORIYUKI HANEDA ◽  
MASAKAZU SAITO ◽  
TOSHIKAZU NISHIO ◽  
...  
Keyword(s):  
Mitral Regurgitation ◽  
Rheumatic Fever ◽  
Acute Rheumatic Fever ◽  
Rheumatic Carditis ◽  
Echocardiographic Findings

Echocardiographic Evaluation of Patients With Acute Rheumatic Fever and Rheumatic Carditis

Circulation ◽  
1996 ◽  
Vol 94 (1) ◽  
pp. 73-82 ◽  
Author(s):  
Ramachandran S. Vasan ◽  
Savitri Shrivastava ◽  
Manam Vijayakumar ◽  
Rajiv Narang ◽  
Bradford C. Lister ◽  
...  
Keyword(s):  
Rheumatic Fever ◽  
Acute Rheumatic Fever ◽  
Rheumatic Carditis ◽  
Echocardiographic Evaluation

Plasma gelsolin as a biomarker of acute rheumatic carditis

2014 ◽  
Vol 25 (7) ◽  
pp. 1276-1280 ◽  
Author(s):  
Mustafa Argun ◽  
Ali Baykan ◽  
Figen Narin ◽  
Abdullah Özyurt ◽  
Özge Pamukçu ◽  
...  
Keyword(s):  
Rheumatic Fever ◽  
Acute Rheumatic Fever ◽  
Systemic Disease ◽  
Regulatory Protein ◽  
Left Ventricular ◽  
Healthy Controls ◽  
Human Beings ◽  
Rheumatic Carditis ◽  
Healthy Human ◽  
Plasma Gelsolin

AbstractBackgroundAcute rheumatic fever is an autoimmune, inflammatory, and multi-systemic disease secondary to pharyngitis and is caused by group A streptococcus. In developing countries, acute rheumatic fever is the most common cause of acquired heart disease. Gelsolin is a calcium-dependent, multi-functional actin-regulatory protein circulating in the plasma of healthy human beings. The correlation between blood gelsolin levels and inflammatory conditions suggests the potential benefit of gelsolin as a prognostic marker. The aim of the present study was to appraise the association of gelsolin and acute rheumatic carditis in childhood.Materials and MethodsPlasma gelsolin levels were measured and echocardiographic examinations were performed in patients (n=37) with acute rheumatic carditis and compared with those of age- and gender-matched healthy controls (n=24).ResultsThe plasma gelsolin levels in children with acute rheumatic carditis were significantly lower compared with controls (197±218 versus 322±255 mg/L, p=0.039). There was a significant correlation among gelsolin levels and the grade of mitral regurgitation (p=0.030), left ventricular end-diastolic diameter (p=0.017), and left ventricular end-systolic diameter (p=0.028) at diagnosis.ConclusionsLevels of the gelsolin plasma isoform were decreased in patients with acute rheumatic carditis compared with healthy controls. Gelsolin may be used as a biochemical marker for acute rheumatic carditis.

Long-term observations of rheumatic carditis

1992 ◽  
Vol 2 (3) ◽  
pp. 254-260 ◽  
Author(s):  
Kalim-ud-Din Aziz ◽  
L. Cheema ◽  
A.D. Memon
Keyword(s):  
Heart Disease ◽  
Rheumatic Fever ◽  
Acute Rheumatic Fever ◽  
Recurrent Infection ◽  
Secondary Prophylaxis ◽  
First Episode ◽  
Initial Attack ◽  
Rheumatic Carditis ◽  
Rheumatic Heart

AbstractA total of 246 consecutive patients were seen with the diagnosis of acute rheumatic fever (and/or rheumatic heart disease) and were followed for 587.7 patient years. The episode of acute rheumatic fever was the first in 64 of these patients, whereas recurrent acute rheumatic fever was seen in 26 and the other 156 patients had chronic rheumatic carditis. At presentation, those suffering an initial attack had less frequent and less severe carditis when compared to those suffering recurrent infection (p<0.05). Improvement in carditis during follow-up was noted in those having an initial attack (p<0.1), while deterioration occurred following recurrent infection (p<0.01), and no change was noted for those with chronic infection. Recurrences of acute rheumatic fever were most frequent in those presenting with their initial infection (21%) or reinfection (35%), and dropout from follow-up was highest in the group with first infection (38%) compared to those with recurrent infection (15%) and chronic carditis (25%). Non-recognition of the first episode of acute rheumatic fever and failure of secondary prophylaxis were found to be the major contributors to the observed increased pool of recurrent and chronic rheumatic heart disease. We conclude that, in the absence of programmed primary prophylaxis of acute rheumatic fever, the best chance of controlling the progression of carditis or affecting cure is to recognize the first episode ofacute rheumatic fever and then ensure strict adherence to secondary prophylaxis. Since the prognosis of recurrent carditis is poor, the best management of moderate to severe recurrent carditis is early reparative valvar surgery wherever possible.

Treatment of rheumatic carditis with intravenous gammaglobulin: is there a beneficial effect?

2001 ◽  
Vol 11 (5) ◽  
pp. 565-567 ◽  
Author(s):  
Karim A. Diab ◽  
Majd Ariss Timani ◽  
Fadi F. Bitar
Keyword(s):  
Heart Disease ◽  
Beneficial Effect ◽  
Rheumatic Fever ◽  
Intravenous Immunoglobulin ◽  
Conventional Therapy ◽  
Acute Rheumatic Fever ◽  
High Dose ◽  
Rheumatic Carditis ◽  
Intravenous Gammaglobulin

Rheumatic carditis is a major manifestation of acute rheumatic fever. Conventional therapy includes the use of salicylates and steroids. To date, however, such therapy has not been proven to have a clear benefit in reducing valvar heart disease. We report the use of high-dose intravenous immunoglobulin in two chidlren with acute rheumatic carditis in whom we have been able to document the beneficial effect.

Corea, artrite, eritema marginato: malattia reumatica e diagnosi differenziali

2020 ◽  
Vol 39 (10) ◽  
pp. 643-650
Author(s):  
Antonino Maria Quintilio Alberio ◽  
Filippo Pieroni ◽  
Giulia Bini ◽  
Alice Bonucelli ◽  
Alessandro Orsini ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Rheumatic Disease ◽  
Rheumatic Fever ◽  
American Heart Association ◽  
Acute Rheumatic Fever ◽  
American Heart ◽  
Heart Association ◽  
Rheumatic Carditis ◽  
Critical Reasoning ◽  
Clinical Onset

Acute rheumatic fever, Rheumatic carditis, Sydenham’s chorea, Erythema marginatum, Arthritis, Differential diagnosis The revision of the Jones criteria by the American Heart Association allowed the identification and diagnosis of a greater number of cases of Rheumatic Disease (RD); however, the higher incidence of RD is associated with "pathomorphic" phenotypic pictures, making the diagnosis more difficult. Chorea, carditis, arthritis, marginatum erythema are the major criteria for the diagnosis of RD and can represent its clinical onset, but likewise, due to the variety of their associations, they open a range of different differential diagnoses. Through the critical reasoning applied to some clinical cases, these major “criteria” of RD have been discussed to reduce the difficulties of the differential diagnosis.

Rheumatic Nodules Wanted

PEDIATRICS ◽  
1968 ◽  
Vol 42 (5) ◽  
pp. 873-873
Author(s):  
Bernice G. Wedum
Keyword(s):  
Tissue Culture ◽  
Rheumatic Fever ◽  
Acute Rheumatic Fever ◽  
Rheumatic Carditis ◽  
Culture Studies

In the course of tissue culture studies on the pathogenesis of rheumatic fever, we are in need of rheumatic nodules which have recently formed in the course of rheumatic carditis. These structures have become rare due to the recent decrease in the prevalence and severity of acute rheumatic fever and the widespread use of steroids. The nodule should be situated on the extremities, be readily accessible to biopsy, and, preferably, be just in the process of forming, although nodules of any age would be welcome.

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