Differential Diagnoses for Unpopularity

Limbic encephalitis is often reported to present as seizures and impaired cognition with little focus on psychiatric presentations. In this case report, we present a 49-year-old man who initially presented to the Psychiatric Liaison Service with a several month history of confusion with the additional emergence of visual hallucinations and delusions. Due to the inconsistent nature of the symptoms in the context of a major financial stressor, a provisional functional cognitive impairment diagnosis was made. Investigations later revealed a positive titre of voltage-gated potassium channel (VGKC) antibodies, subtype leucine-rich glioma inactivated 1 accounting for his symptoms which dramatically resolved with steroids and immunoglobulins. This case highlighted the need for maintaining broad differential diagnoses in a patient presenting with unusual psychiatric symptoms.

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A case of splenomegaly with RK-39 positivity: A diagnostic pitfall

Tropical Doctor ◽

10.1177/00494755211020610 ◽

2021 ◽

pp. 004947552110206

Author(s):

Prasad Dange ◽

Ankesh Gupta ◽

Richa Juneja ◽

Renu Saxena

Keyword(s):

Hereditary Spherocytosis ◽

Correct Diagnosis ◽

Young Male ◽

Differential Diagnoses ◽

Patient Evaluation ◽

Serological Testing ◽

Endemic Region ◽

Careful Patient ◽

Diagnostic Pitfall ◽

Marked Splenomegaly

Long-standing moderate to marked splenomegaly suggests several differential diagnoses, both haematological and infectious, particularly leishmaniasis and malaria in endemic areas. Non-infectious causes may be missed in these regions, especially if pitfalls of serological testing are not considered. Careful patient evaluation is necessary to arrive at the correct diagnosis. We report a case of a young male whose hereditary spherocytosis was initially missed because of RK-39 positivity, splenomegaly and the fact that he hailed from an endemic region.

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Cholesterol Granuloma of the Maxillary Sinus—A Case Report and Literature Review

Allergy & Rhinology ◽

10.1177/2152656720984785 ◽

2021 ◽

Vol 12 ◽

pp. 215265672098478

Author(s):

Abdulrahman Alghulikah ◽

Norah Musallam ◽

Ibrahim Sumaily ◽

Amany Fathaddin ◽

Surayie Aldossary

Keyword(s):

Case Report ◽

Literature Review ◽

Maxillary Sinus ◽

Review Article ◽

Unusual Presentation ◽

Differential Diagnoses ◽

Anatomical Site ◽

Cholesterol Granuloma ◽

Comprehensive Literature Review

Cholesterol Granulomas of the Maxillary Sinus, considered an unusual presentation at this anatomical site. Over last 2 decades, only few cases are reported in the literature (English) and no available comprehensive reviews or studies on this entity. Herein in this article we present a comprehensive literature review of the available reports of 16 cases along with reporting a new case which we managed, aided with its histopathological pictures. This review article can be a reference for practitioners in the field of otorhinolaryngology who may encounter these cases. Also, it attracts the attention to consider this pathology among the differential diagnoses of nasal masses. Moreover, including a described pathological imaging may help young pathologist to identify this pathology.

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Characteristics and Clinical Value of 18F-FDG PET/CT in the Management of Adult-Onset Still’s Disease: 35 Cases

Journal of Clinical Medicine ◽

10.3390/jcm10112489 ◽

2021 ◽

Vol 10 (11) ◽

pp. 2489

Author(s):

Josselin Brisset ◽

Yvan Jamilloux ◽

Stephanie Dumonteil ◽

Guillaume Lades ◽

Martin Killian ◽

...

Keyword(s):

Bone Marrow ◽

Lymph Node ◽

Differential Diagnoses ◽

Adult Onset Still’S Disease ◽

Still’S Disease ◽

Clinical Value ◽

Fdg Uptake ◽

Pet Ct ◽

18F Fdg ◽

Adult Onset Still's Disease

While the diagnosis of adult-onset Still’s disease (AOSD) involves the exclusion of differential diagnoses, the characteristics and value of 18F-Fluorodeoxyglucose (18F-FDG) Positron Emission Tomography coupled with CT (PET/CT) in the management of AOSD remain poorly known. Our retrospective study included patients from four centers, fulfilling Yamaguchi or Fautrel criteria, who underwent a PET/CT during an active AOSD. Thirty-five patients were included. At the time of PET/CT, the Yamaguchi criteria were met in 23 of 29 evaluable cases. PET/CT showed bone marrow (74.3%), lymph node (74.3%), and splenic (48.6%) FDG uptake. Despite arthralgia or arthritis in most patients, joints were rarely the sites of 18F-FDG accumulation. The spatial distribution of 18F-FDG uptake was nonspecific, and its intensity could be similar to malignant disease. Lymph node or bone marrow biopsy was performed after PET/CT in 20 patients (57.1%). The intensity of bone marrow; splenic and lymph node hypermetabolism appeared to be correlated with disease activity. Abnormal PET/CT in the cervical lymph nodes and age ≥ 60 years seemed to be predictive factors for monocyclic evolution. The clinical value of PET/CT is not in direct diagnosis; but as an aid in excluding differential diagnoses by searching for their scintigraphic features and guiding biopsy.

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Dyspareunia

InnovAiT Education and inspiration for general practice ◽

10.1177/17557380211030299 ◽

2021 ◽

pp. 175573802110302

Author(s):

Charlotte Morris ◽

Catherine Briggs ◽

Manju Navani

Keyword(s):

Quality Of Life ◽

Primary Care ◽

Healthcare Professionals ◽

Persistent Pain ◽

Differential Diagnoses ◽

Relationship Problems

Dyspareunia is persistent pain on attempted or successful vaginal penetration. It is under-reported, infrequently asked about by healthcare professionals, and affects quality of life and relationships. Dyspareunia is multifactorial and possesses biopsychosocial components. Pain may be distinct and localised, deep or persistent. Among the symptoms, women describe sensations of aching, throbbing and tearing. Disinterest in sex and relationship problems can result. This article discusses dyspareunia, its common differential diagnoses and aims to improve clinician confidence in assessing and managing dyspareunia in primary care.

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Gorham Stout disease: a case report from Syria

Oxford Medical Case Reports ◽

10.1093/omcr/omaa121 ◽

2021 ◽

Vol 2021 (1) ◽

Author(s):

Asil Esper ◽

Sami Alhoulaiby ◽

Areege Emran ◽

Safwan Youssef ◽

Zuheir Alshehabi

Keyword(s):

Case Report ◽

Femoral Head ◽

Bone Formation ◽

Clinical Picture ◽

Bone Matrix ◽

Differential Diagnoses ◽

Rare Entity ◽

Relative Improvement ◽

Cellular Atypia ◽

Pathologic Fractures

Abstract Gorham-Stout disease (GSD) is a rare entity that destroys the bone matrix resulting mainly in osteolysis, pain and pathologic fractures among a broader clinical picture. We report a case of a 60-year-old female with a sudden discovery of pathologic fractures in the pelvis and the absence of the left femoral head. On biopsy, no cellular atypia was found, instead disturbed bone formation with prominent vascularity with scattered foci of necrosis & osteolysis, which lead to the diagnosis of GSD. Possible differential diagnoses were discussed and excluded. The patient was put on Bisphosphonate that led to a relative improvement in the symptoms. This disease needs a more thorough investigation to identify the key cause, what is beyond the scope of this report.

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Differential diagnoses of severe COVID‐19 in tropical areas: The experience of Reunion Island

Tropical Medicine & International Health ◽

10.1111/tmi.13542 ◽

2020 ◽

Author(s):

Pauline Krol ◽

Nathalie Coolen‐Allou ◽

Laura Teysseyre ◽

Nicolas Traversier ◽

Floryan Beasley ◽

...

Keyword(s):

Differential Diagnoses ◽

Reunion Island ◽

Réunion Island ◽

Tropical Areas

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