Pharmacological profile of a new anti-lipolytic agent: 5-methyl-pyrazine-2-carboxylic acid 4-oxide (acipimox) I — Mechanism of action

1981 ◽  
Vol 13 (2) ◽  
pp. 151-161 ◽  
Author(s):  
P.P. Lovisolo ◽  
G. Briatico-Vangosa ◽  
G. Orsini ◽  
R. Ronchi ◽  
R. Angelucci ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Mechanism Of Action ◽  
Pharmacological Profile

scholarly journals Synthesis and ADMET Study of Some 1, 8-Naphthyidine and Quinoline 3-Carboxylic Acid Derivatives

2021 ◽  
Vol 9 (11) ◽  
pp. 1932-1938
Author(s):  
Vinod Kumar Gurjar
Keyword(s):  
Carboxylic Acid ◽  
Virtual Screening ◽  
Heterocyclic Compound ◽  
Mechanism Of Action ◽  
In Silico ◽  
Heterocyclic Compounds ◽  
Analytical Techniques ◽  
Drug Resistant ◽  
Alternate Mechanism ◽  
Selection Of

Abstract: The extremely drug resistant may be a worldwide public ill health in recent years. Molecules with newer targets and an alternate mechanism of action is an urgent requirement of improvement of latest drugs. The utilization of heterocyclic compounds has been increased dramatically over the last 70 years due to their wide selection of technical applications and their favorable environmental and toxicological properties The 1,8-naphthyridine and quinoline 3-carboxylic acid derivatives that we'll manufacture during this method will change the potency and specificity of fluoroquinolones. Taking under consideration the findings, the goal is to style and manufacture 1, 8-naphthyridine and quinoline 3-carboxylic acid derivatives. The synthesized compounds are going to be characterized using multiple analytical techniques, virtual screening, and in-silico ADME/T prediction. Keywords: 1, 8-Naphthyridine, Quinoline, ADMET, Heterocyclic Compound

scholarly journals Dydrogesterone: pharmacological profile and mechanism of action as luteal phase support in assisted reproduction

2019 ◽  
Vol 38 (2) ◽  
pp. 249-259 ◽  
Author(s):  
Georg Griesinger ◽  
Herman Tournaye ◽  
Nick Macklon ◽  
Felice Petraglia ◽  
Petra Arck ◽  
...  
Keyword(s):  
Assisted Reproduction ◽  
Mechanism Of Action ◽  
Luteal Phase ◽  
Pharmacological Profile ◽  
Luteal Phase Support

scholarly journals Agomelatine: mechanism of action and pharmacological profile in relation to antidepressant properties

2014 ◽  
Vol 171 (15) ◽  
pp. 3604-3619 ◽  
Author(s):  
B Guardiola-Lemaitre ◽  
C De Bodinat ◽  
P Delagrange ◽  
M J Millan ◽  
C Munoz ◽  
...  
Keyword(s):  
Mechanism Of Action ◽  
Pharmacological Profile

Studies of the the mechanism of action of 1-aminocyclopentane-1-carboxylic acid

1963 ◽  
Vol 12 (4) ◽  
pp. 303-316 ◽  
Author(s):  
William R. Sterling ◽  
J.Frank Henderson
Keyword(s):  
Carboxylic Acid ◽  
Mechanism Of Action

Importance of 5/6-aryl substitution on the pharmacological profile of 4ʹ-((2-propyl-1H-benzo[d]imidazol-1-yl)methyl)-[1,1ʹ-biphenyl]-2-carboxylic acid derived PPARγ agonists

2017 ◽  
Vol 126 ◽  
pp. 590-603 ◽  
Author(s):  
Victoria Obermoser ◽  
Robert Mauersberger ◽  
Daniela Schuster ◽  
Monika Czifersky ◽  
Marina Lipova ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Pharmacological Profile ◽  
Pparγ Agonists
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