An extremely simple, convenient and mild one-pot reduction of carboxylic acids to alcohols using 3,4,5-trifluorophenylboronic acid and sodium borohydride

2003 ◽  
Vol 44 (16) ◽  
pp. 3427-3428 ◽  
Author(s):  
R.H. Tale ◽  
K.M. Patil ◽  
S.E. Dapurkar
Keyword(s):  
Carboxylic Acids ◽  
Sodium Borohydride ◽  
One Pot

Synthesis of 3-(Cyclohexylamino)-2-arylimidazo[1,2-a]pyridine-8- carboxylic Acids Via an Efficient Three-component Condensation Reaction between Cyclohexylisocyanide and 2-Aminopyridine-3-carboxylic Acid in the Presence of Aromatic Aldehyde

2018 ◽  
Vol 21 (4) ◽  
pp. 298-301 ◽  
Author(s):  
Ghasem Marandi
Keyword(s):  
Biological Sciences ◽  
Carboxylic Acid ◽  
Carboxylic Acids ◽  
High Performance ◽  
Condensation Reaction ◽  
Aromatic Aldehydes ◽  
New Materials ◽  
One Pot ◽  
High Yields ◽  
Benzaldehyde Derivatives

Aim and Objective: The reaction of cyclohexylisocyanide and 2-aminopyridine-3- carboxylic acid in the presence of benzaldehyde derivatives in ethanol led to 3-(cyclohexylamino)-2- arylimidazo[1,2-a]pyridine-8-carboxylic acids in high yields. In a three component condensation reaction, isocyanide reacts with 2-aminopyridine-3-carboxylic acid and aromatic aldehydes without any prior activation. Material and Methods: The synthesized products have stable structures which have been characterized by IR, 1H, 13C and Mass spectroscopy as well as CHN-O analysis. Results: In continuation of our attempts to develop simple one-pot routes for the synthesis of 3- (cyclohexylamino)-2-arylimidazo[1,2-a]pyridine-8-carboxylic acids, aromatic aldehydes with divers substituted show a high performance. Conclusion: In conclusion, this study introduces the art of combinatorial chemistry using a simple one-pot procedure for the synthesis of new materials which are interesting compounds in medicinal and biological sciences.

Mild one-pot conversion of carboxylic acids to amides or esters with Ph3P/trichloroisocyanuric acid

2005 ◽  
Vol 46 (35) ◽  
pp. 5945-5947 ◽  
Author(s):  
Rogério da C. Rodrigues ◽  
Igor M.A. Barros ◽  
Edson L.S. Lima
Keyword(s):  
Carboxylic Acids ◽  
One Pot ◽  
Trichloroisocyanuric Acid

One-Pot Reductive Amination of Carbonyl Compounds Using Sodium Borohydride–Amberlyst 15

2010 ◽  
Vol 40 (7) ◽  
pp. 951-956 ◽  
Author(s):  
Heshmatollah Alinezhad ◽  
Mahmood Tajbakhsh ◽  
Nastaran Mahdavi
Keyword(s):  
Sodium Borohydride ◽  
Carbonyl Compounds ◽  
Reductive Amination ◽  
One Pot ◽  
Amberlyst 15

Amides in One Pot from Carboxylic Acids and Amines via Sulfinylamides

2014 ◽  
Vol 16 (2) ◽  
pp. 604-607 ◽  
Author(s):  
Jianfei Bai ◽  
Bartosz K. Zambroń ◽  
Pierre Vogel
Keyword(s):  
Carboxylic Acids ◽  
One Pot

scholarly journals Facile reduction of intermediates from carboxylic acids and 6-nitro-1-(2-nitrophenylsulfonyloxy)benzotriazole with sodium borohydride to alcohols.

1988 ◽  
Vol 36 (9) ◽  
pp. 3628-3631 ◽  
Author(s):  
TADASHI OKAWARA ◽  
NORIHIRO IKEDA ◽  
TETSUO YAMASAKI ◽  
MITSURU FURUKAWA
Keyword(s):  
Carboxylic Acids ◽  
Sodium Borohydride
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