Role of TYR70 in the N-glycosidase activity of neo-trichosanthin

Toxicon ◽  
1999 ◽  
Vol 37 (7) ◽  
pp. 961-972 ◽  
Author(s):  
Li Yan ◽  
Shen Wu ◽  
Hui-Guang Li ◽  
Jian-Hui Li ◽  
R.N.-S Wong ◽  
...  
Keyword(s):  
Glycosidase Activity

scholarly journals Role of cathepsin A and cathepsin C in the regulation of glycosidase activity

2012 ◽  
Vol 50 (1) ◽  
pp. 20-24 ◽  
Author(s):  
Alina Minarowska ◽  
Łukasz Minarowski ◽  
Alicja Karwowska ◽  
Anna Justyna Milewska ◽  
Marek Gacko
Keyword(s):  
Cathepsin C ◽  
Glycosidase Activity

scholarly journals Role of Arg163 in the N-glycosidase activity of neo-trichosanthin

1999 ◽  
Vol 12 (11) ◽  
pp. 999-1004 ◽  
Author(s):  
Hui-Guang Li ◽  
Shi-Zhen Xu ◽  
Shen Wu ◽  
Li Yan ◽  
Jian-Hui Li ◽  
...  
Keyword(s):  
Glycosidase Activity

scholarly journals Determination of glycosidase activity in porcine oviductal fluid at the different phases of the estrous cycle

Reproduction ◽  
2008 ◽  
Vol 136 (6) ◽  
pp. 833-842 ◽  
Author(s):  
Luis César Carrasco ◽  
Raquel Romar ◽  
Manuel Avilés ◽  
Joaquín Gadea ◽  
Pilar Coy
Keyword(s):  
Estrous Cycle ◽  
Molecular Mechanisms ◽  
Follicular Phase ◽  
Hydrolytic Cleavage ◽  
Glycosidase Activity ◽  
Early Follicular Phase ◽  
Oviductal Fluid ◽  
Late Follicular Phase

Sperm–oocyte binding and gamete–oviductal epithelium interactions are carbohydrate-mediated events occurring in the oviductal fluid (OF). Thus, knowledge about the activities of glycosidases (enzymes catalyzing hydrolytic cleavage of terminal sugar residues) in this milieu would help us understand the molecular mechanisms involved in these events. This work was carried out to investigate the glycosidase activity, protein content, and volume of OF collected from gilts and sows. Oviducts were classified into four phases of the estrous cycle (early follicular, late follicular, early luteal, and late luteal) based on the appearance of the ovaries. OF was aspirated, centrifuged, measured for volume, and frozen until assay. Substrates conjugated to 4-methylumbelliferyl were used to screen the activities of seven different glycosidases at physiological pH (7.2). α-l-Fucosidase and β-N-acetyl-glucosaminidase activities increased at the late follicular phase to decrease after ovulation. β-d-Galactosidase, α-d-mannosidase, and β-N-acetyl-galactosaminidase showed higher activities at the early follicular phase, which decreased after ovulation. N-Acetyl-neuraminidase and α-d-galactosidase did not show activity at any phase of estrous cycle neither in sows nor in gilts at pH 7.2, although it did at acidic pH (4.4) in the follicular and luteal phase samples. Total protein also changed during the cycle showing the maximum secretion at the late follicular phase (2118.6±200.7 μg/oviduct). The highest volumes of OF were collected from the oviducts at the late follicular phase (50.7±1.3 μl/oviduct). These results indicate that OF from sows and gilts shows glycosidase activity varying throughout the estrous cycle suggesting a role of these enzymes in carbohydrate-mediated events.

Role of dactinomycin in the improved survival of children with Wilms' tumor

JAMA ◽  
1966 ◽  
Vol 195 (12) ◽  
pp. 1005-1009 ◽  
Author(s):  
D. J. Fernbach
Keyword(s):  
Wilms Tumor

Role of the allergist in diagnosis and management of patients with uveitis

JAMA ◽  
1966 ◽  
Vol 195 (3) ◽  
pp. 167-172 ◽  
Author(s):  
T. E. Van Metre
Keyword(s):  
Diagnosis And Management

The power of norms to sway fused group members

2018 ◽  
Vol 41 ◽  
Author(s):  
Winnifred R. Louis ◽  
Craig McGarty ◽  
Emma F. Thomas ◽  
Catherine E. Amiot ◽  
Fathali M. Moghaddam
Keyword(s):  
Evolutionary Anthropology ◽  
Normative Systems ◽  
Violent Extremism ◽  
Identity Fusion ◽  
Group Members

AbstractWhitehouse adapts insights from evolutionary anthropology to interpret extreme self-sacrifice through the concept of identity fusion. The model neglects the role of normative systems in shaping behaviors, especially in relation to violent extremism. In peaceful groups, increasing fusion will actually decrease extremism. Groups collectively appraise threats and opportunities, actively debate action options, and rarely choose violence toward self or others.

Elaborating the role of reflection and individual differences in the study of folk-economic beliefs

2018 ◽  
Vol 41 ◽  
Author(s):  
Kevin Arceneaux
Keyword(s):  
Decision Making ◽  
Individual Differences ◽  
Cognitive Processes ◽  
Evolutionary History ◽  
Behavioral Responses ◽  
History Of ◽  
Economic Beliefs

AbstractIntuitions guide decision-making, and looking to the evolutionary history of humans illuminates why some behavioral responses are more intuitive than others. Yet a place remains for cognitive processes to second-guess intuitive responses – that is, to be reflective – and individual differences abound in automatic, intuitive processing as well.

The role of affect in feelings of obligation

2020 ◽  
Vol 43 ◽  
Author(s):  
Stefen Beeler-Duden ◽  
Meltem Yucel ◽  
Amrisha Vaish
Keyword(s):  
Positive Emotions ◽  
The Creation ◽  
Sense Of Obligation

Abstract Tomasello offers a compelling account of the emergence of humans’ sense of obligation. We suggest that more needs to be said about the role of affect in the creation of obligations. We also argue that positive emotions such as gratitude evolved to encourage individuals to fulfill cooperative obligations without the negative quality that Tomasello proposes is inherent in obligations.

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