Discovery and clinical development of HIV-1 protease inhibitors

2001 ◽  
pp. 213-251 ◽  
Author(s):  
Joel R. Huff ◽  
James Kahn
Keyword(s):  
Protease Inhibitors ◽  
Clinical Development ◽  
Hiv 1

New Aza-Dipeptide Analogues as Potent and Orally Absorbed HIV-1 Protease Inhibitors:  Candidates for Clinical Development

1998 ◽  
Vol 41 (18) ◽  
pp. 3387-3401 ◽  
Author(s):  
Guido Bold ◽  
Alexander Fässler ◽  
Hans-Georg Capraro ◽  
Robert Cozens ◽  
Thomas Klimkait ◽  
...  
Keyword(s):  
Protease Inhibitors ◽  
Clinical Development ◽  
Dipeptide Analogues ◽  
Hiv 1

An oral high dose of cholecalciferol restores vitamin D status in deficient postmenopausal HIV-1 infected women independently of protease inhibitors therapy

2015 ◽  
Author(s):  
Jessica Pepe ◽  
Ivano Mezzaroma ◽  
Alessandra Fantauzzi ◽  
Mario Falciano ◽  
Alessandra Salotti ◽  
...  
Keyword(s):  
Vitamin D ◽  
Protease Inhibitors ◽  
High Dose ◽  
Vitamin D Status ◽  
Hiv 1

A convergent synthesis of the spiroketal moiety of the HIV-1 protease inhibitors didemnaketals

Tetrahedron ◽  
2002 ◽  
Vol 58 (9) ◽  
pp. 1697-1708 ◽  
Author(s):  
Yan Xing Jia ◽  
Xin Li ◽  
Bin Wu ◽  
Xue Zhi Zhao ◽  
Yong Qiang Tu
Keyword(s):  
Protease Inhibitors ◽  
Convergent Synthesis ◽  
Hiv 1

scholarly journals Dual inhibition of SARS-CoV-2 and human rhinovirus with protease inhibitors in clinical development

2021 ◽  
Vol 187 ◽  
pp. 105020
Author(s):  
Cheng Liu ◽  
Sandro Boland ◽  
Michael D. Scholle ◽  
Dorothee Bardiot ◽  
Arnaud Marchand ◽  
...  
Keyword(s):  
Protease Inhibitors ◽  
Clinical Development ◽  
Human Rhinovirus ◽  
Dual Inhibition

scholarly journals Substrate Envelope-Designed Potent HIV-1 Protease Inhibitors to Avoid Drug Resistance

2013 ◽  
Vol 20 (9) ◽  
pp. 1116-1124 ◽  
Author(s):  
Madhavi N.L. Nalam ◽  
Akbar Ali ◽  
G.S. Kiran Kumar Reddy ◽  
Hong Cao ◽  
Saima G. Anjum ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Protease Inhibitors ◽  
Hiv 1 ◽  
Substrate Envelope

Design and Evaluation of Novel Piperidine HIV-1 Protease Inhibitors with Potency against DRV-resistant Variants

2021 ◽  
pp. 113450
Author(s):  
Mei Zhu ◽  
Huiyu Zhou ◽  
Ling Ma ◽  
Biao Dong ◽  
Jinming Zhou ◽  
...  
Keyword(s):  
Protease Inhibitors ◽  
Hiv 1

ChemInform Abstract: HIV-1 Protease Inhibitors Based on Acyclic Carbohydrates.

ChemInform ◽  
2010 ◽  
Vol 29 (49) ◽  
pp. no-no
Author(s):  
B. SAMUELSSON ◽  
ET AL. ET AL.
Keyword(s):  
Protease Inhibitors ◽  
Hiv 1

scholarly journals Major drug resistance mutations to HIV-1 protease inhibitors (PI) among patients exposed to PI class failing antiretroviral therapy in São Paulo State, Brazil

PLoS ONE ◽  
2019 ◽  
Vol 14 (10) ◽  
pp. e0223210
Author(s):  
Giselle de Faria Romero Soldi ◽  
Isadora Coutinho Ribeiro ◽  
Cintia Mayumi Ahagon ◽  
Luana Portes Ozório Coelho ◽  
Gabriela Bastos Cabral ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Antiretroviral Therapy ◽  
Protease Inhibitors ◽  
Sao Paulo ◽  
Resistance Mutations ◽  
Paulo State ◽  
Drug Resistance Mutations ◽  
São Paulo State ◽  
Major Drug ◽  
Hiv 1

scholarly journals Novel HIV-1 Protease Inhibitors with Morpholine as the P2 Ligand to Enhance Activity against DRV-Resistant Variants

2020 ◽  
Vol 11 (6) ◽  
pp. 1196-1204
Author(s):  
Mei Zhu ◽  
Yue Dou ◽  
Ling Ma ◽  
Biao Dong ◽  
Fan Zhang ◽  
...  
Keyword(s):  
Protease Inhibitors ◽  
Hiv 1 ◽  
Enhance Activity
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