Determination of selectivity of reactive nitrogen oxide species for various substrates

Author(s):  
David A. Wink ◽  
Matthew B. Grisham ◽  
Allen M. Miles ◽  
Raymond W. Nims ◽  
Murali C. Krishna ◽  
...  
2002 ◽  
Vol 364 (3) ◽  
pp. 625-628 ◽  
Author(s):  
Lincoln W. MORTON ◽  
Natalie C. WARD ◽  
Kevin D. CROFT ◽  
Ian B. PUDDEY

This study investigated the hypothesis that nitration of γ-tocopherol may be an important mechanism for the detoxification of reactive nitrogen oxide species in vivo. Using liquid chromatography—tandem MS we have shown that γ-tocopherol can be nitrated in vivo to form 5-nitro-γ-tocopherol and that concentrations of this compound are elevated in the plasma of subjects with coronary heart disease. In addition, we demonstrate in carotid-artery atherosclerotic plaque that nitration of γ-tocopherol is also evident at levels similar to that seen in the plasma of subjects with coronary heart disease.


2004 ◽  
Vol 385 (1) ◽  
pp. 1-10 ◽  
Author(s):  
L. A. Ridnour ◽  
D. D. Thomas ◽  
D. Mancardi ◽  
M. G. Espey ◽  
K. M. Miranda ◽  
...  

2000 ◽  
Vol 276 (3) ◽  
pp. 1720-1727 ◽  
Author(s):  
Katrina M. Miranda ◽  
Michael G. Espey ◽  
Kenichi Yamada ◽  
Murali Krishna ◽  
Natalie Ludwick ◽  
...  

2009 ◽  
Vol 45 (3) ◽  
pp. 282-291 ◽  
Author(s):  
H. Ito ◽  
K. Iijima ◽  
N. Ara ◽  
K. Asanuma ◽  
H. Endo ◽  
...  

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