Current Neurochemical and Pharmacological Aspects of Biogenic Amines - Their Function, Oxidative Deamination and Inhibition

RSC Advances ◽  
2020 ◽  
Vol 10 (63) ◽  
pp. 38631-38639
Author(s):  
Mitsuo Shoji ◽  
Takeshi Murakawa ◽  
Mauro Boero ◽  
Yasuteru Shigeta ◽  
Hideyuki Hayashi ◽  
...  

Copper amine oxidases catalyze the oxidative deamination of biogenic amines. We investigated the unique protonation states in the active site using first-principle calculations.


2017 ◽  
Vol 66 (5) ◽  
pp. 870-874 ◽  
Author(s):  
N. S. Nikolaeva ◽  
Yu. V. Soldatova ◽  
A. V. Smolina ◽  
A. Yu. Aksinenko ◽  
V. B. Sokolov ◽  
...  

2007 ◽  
Vol 7 ◽  
pp. 888-902 ◽  
Author(s):  
Emanuela Masini ◽  
Danielle Bani ◽  
Cosimo Marzocca ◽  
Mircea Alexandru Mateescu ◽  
Pier Francesco Mannaioni ◽  
...  

Amine oxidases (AOs) are ubiquitous enzymes involved in the metabolism of biogenic amines. Copper AOs (Cu-AOs) catalyze the oxidative deamination of primary amine groups of several biogenic amines, such as putrescine, cadaverine, and histamine. In the present review, the effects of a plant amine oxidase (Cu-AO, histaminase, EC1.4.3.6) purified from pea seedlings in the modulation of IgE-mediated allergic reactions, and in the prevention of cardiac and splachnic postischemic reperfusion damage are reported.


1973 ◽  
Author(s):  
Robert J. Barrett ◽  
Elaine Sanders Bush ◽  
Gerald J. Schaefer ◽  
Michael Germain

2020 ◽  
Author(s):  
Ian Mallov ◽  
Fiona Jeeva ◽  
Chris Caputo

Food is often wasted due to real or perceived concerns about preservation and shelf life. Thus, precise, accurate and consumer-friendly methods of indicating whether food is safe for consumers are drawing great interest. The colorimetric sensing of biogenic amines released as food degrades is a potential way of determining the quality of the food. Herein, we report the use of genipin, a naturally occurring iridoid, as a dual colorimetric sensor for both oxygen and biogenic amines. Immobilization of genipin in edible calcium alginate beads demonstrates that it is a capable sensor for amine vapors and can be immobilized in a non-toxic, food-friendly matrix.


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