Hidden Markov model-based approach as the first screening of binding peptides that interact with MHC class II molecules

2003 ◽  
Vol 33 (4) ◽  
pp. 472-481 ◽  
Author(s):  
Ryuji Kato ◽  
Hideki Noguchi ◽  
Hiroyuki Honda ◽  
Takeshi Kobayashi
2002 ◽  
Vol 94 (3) ◽  
pp. 264-270 ◽  
Author(s):  
Hideki Noguchi ◽  
Ryuji Kato ◽  
Taizo Hanai ◽  
Yukari Matsubara ◽  
Hiroyuki Honda ◽  
...  

Bioacoustics ◽  
2019 ◽  
Vol 29 (2) ◽  
pp. 140-167 ◽  
Author(s):  
Susannah J. Buchan ◽  
Rodrigo Mahú ◽  
Jorge Wuth ◽  
Naysa Balcazar-Cabrera ◽  
Laura Gutierrez ◽  
...  

2016 ◽  
Vol 23 (19) ◽  
pp. 3175-3195 ◽  
Author(s):  
Ayan Sadhu ◽  
Guru Prakash ◽  
Sriram Narasimhan

A robust hybrid hidden Markov model-based fault detection method is proposed to perform multi-state fault classification of rotating components. The approach presented in this paper enhances the performance of the standard hidden Markov model (HMM) for fault detection by performing a series of pre-processing steps. First, the de-noised time-scale signatures are extracted using wavelet packet decomposition of the vibration data. Subsequently, the Teager Kaiser energy operator is employed to demodulate the time-scale components of the raw vibration signatures, following which the condition indicators are calculated. Out of several possible condition indicators, only relevant features are selected using a decision tree. This pre-processing improves the sensitivity of condition indicators under multiple faults. A Gaussian mixing model-based hidden Markov model (HMM) is then employed for fault detection. The proposed hybrid HMM is an improvement over traditional HMM in that it achieves better separation of the feature space leading to more robust state estimation under multiple fault states and measurement noise scenarios. A simulation employing modulated signals and two experimental validation studies are presented to demonstrate the performance of the proposed method.


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