New approaches in vaccine development

This article discusses the background to the current COVID-19 pandemic. The specific features of the causative pathogen (SARS-CoV-2) are outlined, together with a ‘whistlestop’ revision of immunological principles. The article goes on to discuss the principles and mechanisms of immunisation and the stages of vaccine development. The current situation in relation to the race to develop a vaccine against COVID-19 is incorporated and the immunological principles being adapted by the top contenders are outlined. These include new approaches based on genetic sequencing. Finally, the importance of understanding theoretical principles and the potential practical implications for nurses who will be at the coalface, reassuring patients and delivering vaccines, is addressed.

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New Approaches to Hepatitis A Vaccine Development

10.21236/ada237161 ◽

1991 ◽

Author(s):

Stanley M. Lemon

Keyword(s):

Hepatitis A ◽

Vaccine Development ◽

New Approaches

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New approaches to HIV vaccine development

Current Opinion in Immunology ◽

10.1016/j.coi.2015.05.007 ◽

2015 ◽

Vol 35 ◽

pp. 39-47 ◽

Cited By ~ 58

Author(s):

Barton F Haynes

Keyword(s):

Vaccine Development ◽

Hiv Vaccine ◽

New Approaches

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New approaches to vaccines for endemic and pandemic diseases of Africa with particular focus on building local competencies in Cameroon

Journal of the Cameroon Academy of Sciences ◽

10.4314/jcas.v17i1.6 ◽

2021 ◽

Vol 17 (1) ◽

pp. 75-83

Author(s):

Vincent P.K. Titanji

Keyword(s):

Infectious Diseases ◽

Development Process ◽

Vaccine Development ◽

Production Capacity ◽

Vaccine Production ◽

African Countries ◽

New Approaches ◽

Recent Innovation ◽

Development Pipeline

Vaccines have been recognized as major and effective tools for the control and eventual elimination of infectious diseases and cancer. This brief review examines vaccine classification and development pipeline as well as recent innovations driving the vaccine development process. Using COVID-19 as an example recent innovation in vaccine development are highlighted. The review ends with a call for intensified efforts to build vaccine production capacity in Cameroon and other other African countries. Les vaccins ont été reconnus comme des outils majeurs et efficaces pour le contrôle et l’élimination éventuelle des maladies infectieuses et du cancer. Cette brève revue examine la classification et le pipeline de développement de vaccins ainsi que les innovations récentes à l’origine du processus de développement de vaccins. En utilisant COVID-19 comme exemple, les innovations récentes dans le développement de vaccins sont mises en évidence. La revue se termine par un appel à intensifier les efforts pour renforcer les capacités de production de vaccins au Cameroun et dans d’autres pays africains.

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