Stimulation of glucose and amino acid transport and activation of the insulin signaling pathways by insulin lispro in L6 skeletal muscle cells

1998 ◽  
Vol 20 (1) ◽  
pp. 125-140 ◽  
Author(s):  
Romel Somwar ◽  
Gary Sweeney ◽  
Toolsie Ramlal ◽  
Amira Klip
Keyword(s):  
Skeletal Muscle ◽  
Amino Acid ◽  
Signaling Pathways ◽  
Insulin Signaling ◽  
Insulin Lispro ◽  
Amino Acid Transport ◽  
Muscle Cells ◽  
Acid Transport ◽  
L6 Skeletal Muscle Cells ◽  
Stimulation Of

Ceramide down‐regulates System A amino acid transport and protein synthesis in rat skeletal muscle cells

2004 ◽  
Vol 19 (3) ◽  
pp. 1-24 ◽  
Author(s):  
Russell Hyde ◽  
Eric Hajduch ◽  
Darren J. Powell ◽  
Peter M. Taylor ◽  
Harinder S. Hundal
Keyword(s):  
Skeletal Muscle ◽  
Protein Synthesis ◽  
Amino Acid ◽  
Amino Acid Transport ◽  
Muscle Cells ◽  
Skeletal Muscle Cells ◽  
Acid Transport ◽  
Rat Skeletal Muscle ◽  
System A

Stimulation of transport of alpha-aminoisobutyric acid into the testes of immature mice in vivo by follicle-stimulating hormone

1982 ◽  
Vol 100 (1) ◽  
pp. 137-142
Author(s):  
Nila Oza ◽  
Sarah J. Meanock ◽  
A. G. Davies
Keyword(s):  
Protein Synthesis ◽  
Amino Acid ◽  
Amino Acid Transport ◽  
Specific Activity ◽  
Follicle Stimulating Hormone ◽  
Acid Transport ◽  
Aminoisobutyric Acid ◽  
Old Mice ◽  
Stimulation Of

Abstract. Groups of immature mice were injected sc with radiocarbon-labelled alpha-aminoisobutyric acid (AIB) after being given a single sc injection of hFSH or of 0.9% saline. As an index of the transport of AIB, the specific activity of isotope was measured in homogenates of testis and of liver. FSH treatment caused statistically significant increases in the specific activity of isotope in the testes and in the ratio of testicular to liver specific activity. The effect was greatest in 9-day-old mice injected with FSH 16 h before removal of the testes. Uptake of labelled AIB was not stimulated after administration of hCG or testosterone. Doses of cycloheximide sufficient to reduce the rate of protein synthesis by over 99% did not impair testicular uptake of labelled AIB or the influence of FSH on AIB uptake. These results suggest that FSH stimulates amino acid transport into cells of the immature testis and that this action is independent of the stimulatory effect of FSH on testicular protein synthesis.

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