The Relation between Contact Lens Oxygen Transmissibility and Binding of Pseudomonas aeruginosa to the Cornea after Overnight Wear

Ophthalmology ◽  
1994 ◽  
Vol 101 (2) ◽  
pp. 371-388 ◽  
Author(s):  
Masaki Imayasu ◽  
W. Matthew Petroll ◽  
James V. Jester ◽  
Sanjay K. Patel ◽  
Jun-ichi Ohashi ◽  
...  
2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Vishnu Raghuram ◽  
Joanna B. Goldberg

Pseudomonas aeruginosa is the major cause of bacterial keratitis, a sight-threatening ocular infection that can occur in contact lens wearers, as well as in others. Here, we report the draft genomes of 8 different P. aeruginosa corneal isolates, adding to the list of publicly available corneal infection-associated P. aeruginosa genomes.


Cornea ◽  
1990 ◽  
Vol 9 (3) ◽  
pp. 266???270 ◽  
Author(s):  
Stephen A. Klotz ◽  
Raghunath P. Misra ◽  
Salim I. Butrus

2006 ◽  
Vol 32 (1) ◽  
pp. 12-18 ◽  
Author(s):  
E A. Szliter ◽  
Ronald P. Barrett ◽  
Manal M. Gabriel ◽  
Yunfan Zhang ◽  
Linda D. Hazlett

2009 ◽  
Vol 2009 ◽  
pp. 1-3 ◽  
Author(s):  
Benoit Hue ◽  
Marc Doat ◽  
Gilles Renard ◽  
Marie-Laure Brandely ◽  
François Chast

Purpose. To report a case of microbial keratitis caused by Pseudomonas aeruginosa treated with a combination of acetazolamide and ceftazidime.Methods. Case report.Results. We report the case of a 17-year-old contact lens-wearing female who developed severe keratitis due toPseudomonas aeruginosatemporarily healed with topical fortified antibiotic eye drops. After few days, the patient relapsed, and topical and intravenous ceftazidime were added. Concomitantly, oral administration of acetazolamide was prescribed. This carbonic anhydrase inhibitor was added to the antibiotic regimen in order to decrease the anterior chamber pH, and then, the ceftazidime ionization. By lowering the state of ionization of the antibiotic in the aqueous humor, its concentration was increased. This was confirmed by an improvement of the patient within few days and a rapid eradication of the infection.Conclusion. This is the first reported case of keratitis caused byP. aeruginosasuccessfully treated using acetazolamide as an enhancer of ceftazidime effectiveness.


2000 ◽  
Vol 77 (SUPPLEMENT) ◽  
pp. 174
Author(s):  
Mark D.P. Willcox ◽  
Karen Corrigan ◽  
Adv Cert Chem ◽  
Hua Zhu

2005 ◽  
Vol 3 ◽  
pp. S63
Author(s):  
Manal M. Gabriel ◽  
Ronald P. Barrett ◽  
Linda D. Hazlett ◽  
Elizabeth A. Szliter

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