Azo reduction catalyzed by cytochrome P450 1A2 and NADPH-cytochrome P450 reductase

Journal of Inorganic Biochemistry ◽

10.1016/s0162-0134(97)80245-0 ◽

1997 ◽

Vol 67 (1-4) ◽

pp. 379 ◽

Author(s):

Makoto Umeno ◽

Kazutaka Yanagita ◽

Ikuko Sagami ◽

Toru Shimizu

Keyword(s):

Cytochrome P450 ◽

Cytochrome P450 Reductase ◽

Cytochrome P450 1A2 ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Azo Reduction ◽

Nadph Cytochrome P450 Reductase

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Nitric Oxide Synthesis Capabilities of Cytochrome P450 1A2 and NADPH-Cytochrome P450 Reductase fromNG-Hydroxy-L-Arginine

Chemistry Letters ◽

10.1246/cl.1997.759 ◽

1997 ◽

Vol 26 (8) ◽

pp. 759-760 ◽

Author(s):

Hiroaki Sano ◽

Hideaki Sato ◽

Ikuko Sagami ◽

Toru Shimizu

Keyword(s):

Nitric Oxide ◽

Cytochrome P450 ◽

Cytochrome P450 Reductase ◽

Nitric Oxide Synthesis ◽

Cytochrome P450 1A2 ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Nadph Cytochrome P450 Reductase

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Use of genetically engineeredSalmonella typhimurium OY1002/1A2 strain coexpressing human cytochrome P450 1A2 and NADPH-cytochrome P450 reductase and bacterialO-acetyltransferase in SOS/umu assay

Environmental and Molecular Mutagenesis ◽

10.1002/1098-2280(2000)36:2<121::aid-em6>3.0.co;2-p ◽

2000 ◽

Vol 36 (2) ◽

pp. 121-126 ◽

Author(s):

Pramod Aryal ◽

Takao Terashita ◽

F. Peter Guengerich ◽

Tsutomu Shimada ◽

Yoshimitsu Oda

Keyword(s):

Cytochrome P450 ◽

Cytochrome P450 Reductase ◽

Cytochrome P450 1A2 ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Human Cytochrome ◽

Nadph Cytochrome P450 Reductase

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Biphasic effects of the flavonoids quercetin and naringenin on the metabolic activation of 2-amino-3,5-dimethylimidazo[4,5-f]quinoline by Salmonella typhimurium TA1538 co-expressing human cytochrome P450 1A2, NADPH-cytochrome P450 reductase, and cytochrome b5

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis ◽

10.1016/j.mrfmmm.2003.08.002 ◽

2004 ◽

Vol 545 (1-2) ◽

pp. 37-47 ◽

Author(s):

I Kang

Keyword(s):

Cytochrome P450 ◽

Salmonella Typhimurium ◽

Cytochrome B5 ◽

Metabolic Activation ◽

Cytochrome P450 Reductase ◽

Cytochrome P450 1A2 ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Human Cytochrome ◽

Nadph Cytochrome P450 Reductase

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Recombinant Human Cytochrome P450 1A2 and an N-Terminal-Truncated Form: Construction, Purification, Aggregation Properties, and Interactions with Flavodoxin, Ferredoxin, and NADPH-Cytochrome P450 Reductase

Archives of Biochemistry and Biophysics ◽

10.1006/abbi.1996.0086 ◽

1996 ◽

Vol 327 (1) ◽

pp. 11-19 ◽

Author(s):

Mi-Sook Dong ◽

Hiroshi Yamazaki ◽

Zuyu Guo ◽

F.Peter Guengerich

Keyword(s):

Cytochrome P450 ◽

Cytochrome P450 Reductase ◽

Truncated Form ◽

Cytochrome P450 1A2 ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Human Cytochrome ◽

Nadph Cytochrome P450 Reductase

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Differential Roles of Glu318 and Thr319 in Cytochrome P450 1A2 Catalysis Supported by NADPH-Cytochrome P450 Reductase and tert-Butyl Hydroperoxide

Archives of Biochemistry and Biophysics ◽

10.1006/abbi.1994.1184 ◽

1994 ◽

Vol 310 (2) ◽

pp. 397-401 ◽

Author(s):

K. Hiroya ◽

Y. Murakami ◽

T. Shimizu ◽

M. Hatano ◽

P.R.O. Demontellano

Keyword(s):

Cytochrome P450 ◽

Cytochrome P450 Reductase ◽

Cytochrome P450 1A2 ◽

Butyl Hydroperoxide ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Tert Butyl Hydroperoxide ◽

Nadph Cytochrome P450 Reductase

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Probing the role of lysines and arginines in the catalytic function of cytochrome P450d by site-directed mutagenesis. Interaction with NADPH-cytochrome P450 reductase

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)67801-4 ◽

1991 ◽

Vol 266 (6) ◽

pp. 3372-3375

Author(s):

T Shimizu ◽

T Tateishi ◽

M Hatano ◽

Y Fujii-Kuriyama

Keyword(s):

Cytochrome P450 ◽

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

Cytochrome P450 Reductase ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Catalytic Function ◽

Nadph Cytochrome P450 Reductase

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The cytochrome P450 2B4-NADPH cytochrome P450 reductase electron transfer complex is not formed by charge-pairing.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)42093-5 ◽

1992 ◽

Vol 267 (21) ◽

pp. 14669-14676

Author(s):

A.I. Voznesensky ◽

J.B. Schenkman

Keyword(s):

Electron Transfer ◽

Cytochrome P450 ◽

Cytochrome P450 Reductase ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Cytochrome P450 2B4 ◽

Nadph Cytochrome P450 Reductase ◽

Electron Transfer Complex

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Role of structural factors of antitumour anthraquinone derivatives and analogues in the ability to undergo bioreductive activation by NADPH cytochrome P450 reductase. Implications for increasing the activity against sensitive and multidrug-resistant leukaemia HL60 cells

Anti-Cancer Drugs ◽

10.1097/cad.0b013e32834fcf4f ◽

2012 ◽

Vol 23 (4) ◽

pp. 393-405 ◽

Author(s):

Dorota Kostrzewa-Nowak ◽

Bohdan Bieg ◽

Mark J.I. Paine ◽

C. Roland Wolf ◽

Jolanta Tarasiuk

Keyword(s):

Cytochrome P450 ◽

Multidrug Resistant ◽

Structural Factors ◽

Cytochrome P450 Reductase ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Anthraquinone Derivatives ◽

Nadph Cytochrome P450 Reductase

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Organization of NADPH-Cytochrome P450 Reductase and CYP1A2 in the Endoplasmic Reticulum—Microdomain Localization Affects Monooxygenase Function

Molecular Pharmacology ◽

10.1124/mol.110.068817 ◽

2010 ◽

Vol 79 (3) ◽

pp. 549-557 ◽

Author(s):

Lauren Brignac-Huber ◽

James R. Reed ◽

Wayne L. Backes

Keyword(s):

Endoplasmic Reticulum ◽

Cytochrome P450 ◽

Cytochrome P450 Reductase ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Nadph Cytochrome P450 Reductase

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Role of the prosthetic groups of NADPH-cytochrome P450 reductase in 3-hydroxyanthranilamide-catalyzed, NADPH-dependent superoxide anion production

Redox Report ◽

10.1080/13510002.1996.11747070 ◽

1996 ◽

Vol 2 (5) ◽

pp. 339-344

Author(s):

Y. Ohta ◽

R. Shinohara ◽

I. Ishiguro

Keyword(s):

Cytochrome P450 ◽

Superoxide Anion ◽

Cytochrome P450 Reductase ◽

Superoxide Anion Production ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Anion Production ◽

Nadph Cytochrome P450 Reductase ◽

Prosthetic Groups

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