335 poster Endogenously targeted 211 at alpha-radiation therapy of iodo-refractory metastatic differentiated thyroid cancer

2001 ◽  
Vol 58 ◽  
pp. S90
Keyword(s):  
Radiation Therapy ◽  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
Alpha Radiation

scholarly journals Case of papillary thyroid cancer presenting with an inoperable cervical mass successfully treated with high-dose radiation therapy

2021 ◽  
Vol 14 (11) ◽  
pp. e246084
Author(s):  
Yasuo Kosugi ◽  
Shinichi Ohba ◽  
Fumihiko Matsumoto ◽  
Keisuke Sasai
Keyword(s):  
Radiation Therapy ◽  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
Dose Intensity ◽  
External Beam Radiation ◽  
High Dose ◽  
Treatment Resistant ◽  
Beam Radiation ◽  
Cervical Mass ◽  
High Dose Intensity

External-beam radiation therapy (EBRT) for differentiated thyroid cancer has been controversial. Palliative irradiation is usually recommended for patients with treatment-resistant relapse and/or distant metastases, but high-dose EBRT is not often indicated in this situation. A 50-year-old man had treatment-resistant recurrence of an inoperable cervical mass and multiple lung metastases after total thyroidectomy and neck dissection. Because the patient had good performance status and no other life-threatening metastases, he received high-dose intensity-modulated radiation therapy (IMRT). Remarkably, the tumour shrank during treatment. After 3 months, he had bleeding from the internal carotid artery. The bleeding was outside the high-dose irradiation site and was likely due to infection; emergency interventional radiology was performed. The post-EBRT clinical course was favourable and the cervical mass almost disappeared. The patient remained alive for 3 years post treatment. It is possible to extend the indication of high-dose intensity-IMRT in selected patients with differentiated thyroid cancer.

scholarly journals Update on External Beam Radiation Therapy in Thyroid Cancer

2011 ◽  
Vol 96 (8) ◽  
pp. 2289-2295 ◽  
Author(s):  
James D. Brierley
Keyword(s):  
Radiation Therapy ◽  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
External Beam Radiotherapy ◽  
Anaplastic Thyroid Cancer ◽  
External Beam Radiation ◽  
External Beam ◽  
Primary Therapy ◽  
Beam Radiation ◽  
Effective Radiation

Abstract Surgery is the mainstay of treatment for thyroid cancer. The role for external beam radiotherapy (EBRT) as an adjuvant to surgery or as the primary therapy is established in anaplastic thyroid cancer but is controversial in differentiated thyroid cancer and uncertain in medullary thyroid cancer. This update reviews the recent reported success of combining EBRT with taxanes in anaplastic thyroid cancer. Also discussed are the recent reports from large single institutions that support the recommendations of the American and British Thyroid Associations on the use of EBRT in high-risk differentiated thyroid cancer. Further evidence on the role of EBRT in MTC is discussed. The important advances in the delivery of EBRT using intensity-modulated radiation and image-guided radiation that result in more accurate and potentially more effective radiation therapy with less toxicity are also discussed.

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